Unveiling the power of high-dimensional cytometry data with cyCONDOR.
Nature communications
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DZNE Venusberg-Campus 1 53127 Bonn
Using systems immunology approaches, I am interested in understanding immune cells in health and disease, in particular by bringing single-cell omics technologies to large cohort studies in infectious diseases including COVID-19, sepsis, and HIV. We recently showed for COVID-19 how bulk blood transcriptomics can be used to determine molecular signatures of the disease and facilitate drug repurposing. Further, we have developed an approach for the analysis of multi-layered data from large human cohorts utilizing human variance as a surrogate to analyse functional traits and are applying this in the context of aging and immune system homeostasis.
Nature communications
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Cell
View this publicationNature immunology
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