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Prof. Dr. Alfredo Ramirez

Member

Department of Psychiatry and Psychotherapy, University of Cologne

Kerpener Str. 62, 50931 Cologne

alfredo.ramirez-zuniga@uk-koeln.de

The main objective of Dr. Ramirez’s laboratory is the identification of the genetic and epigenetic architecture that influences the disease processes underlying cognitive disorders such as Alzheimer’s disease. A key focus of his research is identifying the molecular mechanisms at the intersection of ageing and Alzheimer’s disease that drive cognitive decline. His group combines (epi)genomics and proteomics to study cellular senescence, a key mechanism that triggers chronic inflammation through the senescence-associated secretory phenotype (SASP).

Prof. Dr. Alfredo Ramirez

Recent publications

  • Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline.

    Neurology

    Authors: Xiao Wang, Silka D Freiesleben, Luisa-Sophie Schneider, Lukas Preis, Josef Priller, Eike J Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Niels Hansen, Frank Jessen, Ayda Rostamzadeh, Emrah Duzel, Wenzel Glanz, Enise I Incesoy, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan J Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H J Munk, Annika Spottke, Nina Roy-Kluth, Michael T Heneka, Frederic Brosseron, Michael Wagner, Steffen Wolfsgruber, Alfredo Ramirez, Luca Kleineidam, Melina Stark, Oliver Peters

  • Prognostic value of Alzheimer's disease plasma biomarkers in the oldest-old: a prospective primary care-based study.

    The Lancet regional health. Europe

    Authors: Pamela V Martino-Adami, Madhurima Chatterjee, Luca Kleineidam, Siegfried Weyerer, Horst Bickel, Birgitt Wiese, Steffi G Riedel-Heller, Martin Scherer, Kaj Blennow, Henrik Zetterberg, Michael Wagner, Anja Schneider, Alfredo Ramirez

All publications by Prof. Dr. Alfredo Ramirez