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Prof. Dr. Alfredo Ramirez

Member

Department of Psychiatry and Psychotherapy, University of Cologne

Kerpener Str. 62, 50931 Cologne

alfredo.ramirez@uk-koeln.de

The main objective of Dr. Ramirez’s laboratory is the identification of the genetic and epigenetic architecture that influences the disease processes underlying cognitive disorders such as Alzheimer’s disease. A key focus of his research is identifying the molecular mechanisms at the intersection of ageing and Alzheimer’s disease that drive cognitive decline. His group combines (epi)genomics and proteomics to study cellular senescence, a key mechanism that triggers chronic inflammation through the senescence-associated secretory phenotype (SASP).

Prof. Dr. Alfredo Ramirez

Recent publications

  • Microglia protein profiles in CSF across Alzheimer's disease clinical stages.

    Nature aging

    Authors: Elena-Raluca Blujdea, Pieter van Bokhoven, Pamela V Martino-Adami, Victoria S Marshe, Ellen M Vromen, Yanaika S Hok-A-Hin, Walter A Boiten, David J Irwin, Alice S Chen-Plotkin, Afina W Lemstra, Yolande Pijnenburg, Wiesje M van der Flier, Oliver Peters, Julian Hellmann-Regen, Josef Priller, Anja Schneider, Jens Wiltfang, Frank Jessen, Emrah Düzel, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Frederic Brosseron, Marta Del Campo, Ruud Wijdeven, Pieter-Jelle Visser, Betty M Tijms, Philip L De Jager, Alfredo Ramirez, Charlotte E Teunissen, Lisa Vermunt

  • Predicting longitudinal basal forebrain volume in the Alzheimer's disease spectrum: the role of sex and ApoE epsilon 4 genotype.

    Frontiers in neuroscience

    Authors: Alice Grazia, Fedor Levin, Frank Jessen, Michael Wagner, Oliver Peters, Josef Priller, Anja Schneider, Jens Wiltfang, Emrah Düzel, Katharina Buerger, Robert Perneczky, Christoph Laske, Annika Spottke, Alfredo Ramirez, Stefan J Teipel

  • CSF biomarkers of neuroinflammation are associated with regional atrophy.

    Journal of neurology

    Authors: Serap Özlü, Martin Dyrba, Alice Grazia, Frederic Brosseron, Katharina Buerger, Peter Dechent, Emrah Düzel, Michael Ewers, Klaus Fliessbach, Wenzel Glanz, Niels Hansen, Julian Hellmann-Regen, Stefan Hetzer, Daniel Janowitz, Ingo Kilimann, Marie Kronmüller, Christoph Laske, Falk Lüsebrink, David Mengel, Robert Perneczky, Oliver Peters, Josef Priller, Alfredo Ramirez, Boris-Stephan Rauchmann, Ayda Rostamzadeh, Anja Schneider, Sebastian Sodenkamp, Annika Spottke, Eike Jakob Spruth, Matthis Synofzik, Jens Wiltfang, Michael T Heneka, Frank Jessen, Stefan Teipel

All publications by Prof. Dr. Alfredo Ramirez