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Prof. Dr. Alfredo Ramirez

Member

Department of Psychiatry and Psychotherapy, University of Cologne

Kerpener Str. 62, 50931 Cologne

alfredo.ramirez-zuniga@uk-koeln.de

The main objective of Dr. Ramirez’s laboratory is the identification of the genetic and epigenetic architecture that influences the disease processes underlying cognitive disorders such as Alzheimer’s disease. A key focus of his research is identifying the molecular mechanisms at the intersection of ageing and Alzheimer’s disease that drive cognitive decline. His group combines (epi)genomics and proteomics to study cellular senescence, a key mechanism that triggers chronic inflammation through the senescence-associated secretory phenotype (SASP).

Prof. Dr. Alfredo Ramirez

Recent publications

  • Disease stage-specific atrophy markers in Alzheimer's disease.

    medRxiv : the preprint server for health sciences

    Authors: Hannah Baumeister, Helena M Gellersen, Sarah E Polk, René Lattmann, Anika Wuestefeld, Laura E M Wisse, Trevor Glenn, Renat Yakupov, Melina Stark, Luca Kleineidam, Sandra Roeske, Barbara Marcos Morgado, Hermann Esselmann, Frederic Brosseron, Alfredo Ramirez, Falk Lüsebrink, Matthis Synofzik, Björn H Schott, Matthias C Schmid, Stefan Hetzer, Peter Dechent, Klaus Scheffler, Michael Ewers, Julian Hellmann-Regen, Ersin Ersözlü, Eike Spruth, Maria Gemenetzi, Klaus Fliessbach, Claudia Bartels, Ayda Rostamzadeh, Wenzel Glanz, Enise I Incesoy, Daniel Janowitz, Boris-Stephan Rauchmann, Ingo Kilimann, Sebastian Sodenkamp, Marie Coenjaerts, Annika Spottke, Oliver Peters, Josef Priller, Anja Schneider, Jens Wiltfang, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Michael Wagner, Gabriel Ziegler, Frank Jessen, Emrah Düzel, David Berron

  • CSF biomarkers are differentially linked to brain areas high and low in noradrenaline, dopamine and serotonin across the Alzheimer's disease spectrum.

    Brain communications

    Authors: Lena Haag, Elisa Lancini, Renat Yakupov, Gabriel Ziegler, Yeo-Jin Yi, Falk Lüsebrink, Wenzel Glanz, Oliver Peters, Eike Jakob Spruth, Slawek Altenstein, Josef Priller, Luisa Sophie Schneider, Xiao Wang, Lukas Preis, Frederic Brosseron, Nina Roy-Kluth, Klaus Fliessbach, Michael Wagner, Steffen Wolfsgruber, Luca Kleineidam, Alfredo Ramirez, Annika Spottke, Frank Jessen, Jens Wiltfang, Anja Schneider, Niels Hansen, Ayda Rostamzadeh, Katharina Buerger, Michael Ewers, Robert Perneczky, Daniel Janowitz, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H Munk, Michael Heneka, Peter Dechent, Stefan Hetzer, Klaus Scheffler, Emrah Düzel, Matthew J Betts, Dorothea Hämmerer

  • Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects.

    Communications medicine

    Authors: Lara Blömeke, Fabian Rehn, Marlene Pils, Victoria Kraemer-Schulien, Anneliese Cousin, Janine Kutzsche, Tuyen Bujnicki, Silka D Freiesleben, Luisa-Sophie Schneider, Lukas Preis, Josef Priller, Eike J Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Niels Hansen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise I Incesoy, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Christoph Laske, Matthias H Munk, Annika Spottke, Nina Roy, Michael T Heneka, Frederic Brosseron, Michael Wagner, Sandra Roeske, Alfredo Ramirez, Matthias Schmid, Frank Jessen, Oliver Bannach, Oliver Peters, Dieter Willbold

All publications by Prof. Dr. Alfredo Ramirez