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Prof. Dr. Annkristin Heine

Member, Steering-Committee Member

Institute of Experimental Immunology (IEI) & Medical Clinic III

Medical Faculty, University of Bonn University Hospital of Bonn Venusberg - Campus 1 53127 Bonn

annkristin.heine@ukbonn.de

Website

Dr. Heine and her group are interested in the mechanisms governing antigen cross-presentation and cytotoxic T cell induction in the context of anti-tumor immune responses. Effective cancer vaccines should not only induce strong and durable T cell responses, but also optimally modulate the balance between suppressive and stimulatory factors in the tumor microenvironment. The aim of her research is the identification of novel immunotherapeutic strategies that accomplish both, with a special focus on different pathways of dendritic cell licensing and chemokine receptor modulation.

Recent publications

  • The Immunomodulatory Effect of Different FLT3 Inhibitors on Dendritic Cells.

    Cancers

    Authors: Sebastian Schlaweck, Alea Radcke, Sascha Kampmann, Benjamin V Becker, Peter Brossart, Annkristin Heine

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  • Anti-MDA5 autoantibodies predict clinical dynamics of dermatomyositis following SARS-CoV-2 mRNA vaccination: a retrospective statistical analysis of case reports.

    Rheumatology international

    Authors: Christian R Klein, Annkristin Heine, Peter Brossart, Pantelis Karakostas, Valentin Sebastian Schäfer

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  • Dynamics of microcyst-like epithelial changes associated with Belantamab mafodotin therapy in a patient with multiple myeloma-a case report.

    Blood cancer journal

    Authors: Lukas Schloesser, Karin U Loeffler, Annkristin Heine, Frank G Holz, Martina C Herwig-Carl

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