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Prof. Dr. Jan Hasenauer

Member, Steering-Committee Member

Life and Medical Sciences Institute (LIMES) and Hausdorff Center for Mathematics

Hausdorff Center for Mathematics - HCM Room 2.003 Villa Maria, Endenicher Allee 64 53115 Bonn

jan.hasenauer@uni-bonn.de

+49 228 7369446

Website

Our interdisciplinary research unit develops and applies computational methods for the analysis of complex biological processes. We focus on methods facilitating the model-based integration of different datasets, the critical assessment of the availableinformation, the comparison of competing biological hypothesis and the tailored selection of future experiments. Following thephilosophy of Galileo Galilei: "Measure what can be measured, and make measurable what cannot be measured.", we usemodels to reconstruct properties of the system which cannot be assessed experimentally. This results in an improved holisticunderstanding of biological systems. We apply these methods to study cellular signal processing, cell-to-cell variability, and tissueorganisation.

Recent publications

  • Effects of time-of-day on the noradrenaline, adrenaline, cortisol and blood lipidome response to an ice bath.

    Scientific reports

    Authors: Alexander Braunsperger, Maximilian Bauer, Chaima Ben Brahim, Lea Seep, Dominik Tischer, Mirko Peitzsch, Jan Hasenauer, Sieglinde Hechenbichler Figueroa, Anna Worthmann, Joerg Heeren, Kenneth A Dyar, Karsten Koehler, Ana Soriano-Arroquia, Martin Schönfelder, Henning Wackerhage

  • Benchmarking methods for computing local sensitivities in ordinary differential equation models at dynamic and steady states.

    PloS one

    Authors: Polina Lakrisenko, Dilan Pathirana, Daniel Weindl, Jan Hasenauer

  • Federated difference-in-differences with multiple time periods in DataSHIELD.

    iScience

    Authors: Manuel Huth, Carolina Alvarez Garavito, Lea Seep, Laia Cirera, Francisco Saúte, Elisa Sicuri, Jan Hasenauer

All publications by Prof. Dr. Jan Hasenauer