Macrophage-induced enteric neurodegeneration leads to motility impairment during gut inflammation.
EMBO molecular medicine
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Medical Faculty, University of Bonn University Hospital of Bonn Sigmund-Freud-Strasse 25 53127 Bonn
The focus of research are the immunological consequences of operative trauma and their recognition and regulation in post-operative dysfunction of the gastrointestinal tract. The group described and elucidated the immunological pathomechanism of postoperative ileus. Furthermore, the group found that the gastrointestinal field effect - a panenteric inflammation following localized abdominal surgery - is mediated by an immunological response involving resident intestinal macrophages, mesenteric dendritic cells and memory TH1 cells.
EMBO molecular medicine
View this publicationMicrosurgery
View this publicationLangenbeck's archives of surgery
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