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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • Effects of delayed consent on patient characteristics in adult patients with sepsis.

    Intensive care medicine

    Authors: Frank Bloos, Holger Bogatsch, Mihai G Netea, Evangelos J Giamarellos-Bourboulis, Michael Bauer

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  • Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response.

    Cell reports. Medicine

    Authors: Rachel Brandes-Leibovitz, Anca Riza, Gal Yankovitz, Andrei Pirvu, Stefania Dorobantu, Adina Dragos, Ioana Streata, Isis Ricaño-Ponce, Aline de Nooijer, Florentina Dumitrescu, Nikolaos Antonakos, Eleni Antoniadou, George Dimopoulos, Ioannis Koutsodimitropoulos, Theano Kontopoulou, Dimitra Markopoulou, Eleni Aimoniotou, Apostolos Komnos, George N Dalekos, Mihai Ioana, Evangelos J Giamarellos-Bourboulis, Irit Gat-Viks, Mihai G Netea

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  • Trained innate immunity in response to nuclear antigens in systemic lupus erythematosus.

    Journal of autoimmunity

    Authors: Cansu Yanginlar, Nils Rother, Tomas G J M Post, Maaike Jacobs, Inge Jonkman, Montsy Brouns, Sybren Rinzema, Joost H A Martens, Michiel Vermeulen, Leo A B Joosten, Mihai G Netea, Luuk B Hilbrands, Zaheeb A Choudhry, Johan van der Vlag, Raphaël Duivenvoorden

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