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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination.

    Nature aging

    Authors: Wenchao Li, Zhenhua Zhang, Saumya Kumar, Javier Botey-Bataller, Martijn Zoodsma, Ali Ehsani, Qiuyao Zhan, Ahmed Alaswad, Liang Zhou, Inge Grondman, Valerie Koeken, Jian Yang, Gang Wang, Sonja Volland, Tania O Crişan, Leo A B Joosten, Thomas Illig, Cheng-Jian Xu, Mihai G Netea, Yang Li

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  • Integrative analysis reveals the multilateral inflammatory mechanisms of CD14 monocytes in gout.

    Annals of the rheumatic diseases

    Authors: Ahmed Alaswad, Georgiana Cabău, Tania O Crişan, Liang Zhou, Martijn Zoodsma, Javier Botey-Bataller, Wenchao Li, Cristina Pamfil, Mihai G Netea, Tony Merriman, Cheng-Jian Xu, Yang Li, Leo A B Joosten

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  • Innate immune training of osteoclastogenesis promotes inflammatory bone loss in mice.

    Developmental cell

    Authors: Nora Haacke, Hui Wang, Shu Yan, Marko Barovic, Xiaofei Li, Kosuke Nagai, Adelina Botezatu, Aikaterini Hatzioannou, Bettina Gercken, Giulia Trimaglio, Anisha U Shah, Jun Wang, Ling Ye, Mangesh T Jaykar, Martina Rauner, Ben Wielockx, Kyoung-Jin Chung, Mihai G Netea, Lydia Kalafati, George Hajishengallis, Triantafyllos Chavakis

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