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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • DNA methylation landscapes of HIV controllers: an epigenome-wide association study.

    EBioMedicine

    Authors: Manoj Kumar Gupta, Jéssica Cristina Dos Santos, Victoria Ríos Vazquez, Suzanne D E Ruijten, Adriana Navas, Xun Jiang, Zhaoli Liu, Zhenhua Zhang, Javier Botey-Bataller, Onkar Singh, Nadira Vadaq, Albert L Groenendijk, Wilhelm A J W Vos, Marc J T Blaauw, Louise E van Eekeren, Yang Li, Leo A B Joosten, Casper Rokx, Annelies Verbon, Vasiliki Matzaraki, Mihai G Netea, Andre J A M van der Ven, Cheng-Jian Xu

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  • Differential heterologous immunological effects induced by ChAdOx1-S and BNT162b2 COVID-19 vaccines.

    Cellular immunology

    Authors: Elisabeth A Dulfer, Büsra Geckin, Martijn Zoodsma, Leonie S Helder, Wenchao Li, Reinout van Crevel, Josephine S van der Maat, Yang Li, Jorge Domínguez-Andrés, Mihai G Netea

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  • Cytokine-induced memory-like responses in endothelial cells link chronic inflammation to vascular disease risk.

    Molecular omics

    Authors: Kieu T T Le, Nick Keur, Heleen Middelkamp, Thuy Linh Do, Albert van den Berg, Valeria Orlova, Leo A B Joosten, Mihai G Netea, Cisca Wijmenga, Iris Jonkers, Sebo Withoff, Andries D Van der Meer, Vinod Kumar

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