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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • The Interplay between Innate Immune Memory and Adaptive Immunity: Emerging Mechanisms in Alloimmunity.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    Authors: Maaike Jacobs, Lisanne C de Jong, Nils Rother, Luuk B Hilbrands, Leo A B Joosten, Willem J M Mulder, Mihai G Netea, Raphaël Duivenvoorden

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  • Stress-induced trained immunity-A key mechanism linking psychosocial stress, atherosclerosis, and cardiovascular disease.

    FEBS letters

    Authors: Dineke C W Touw, Saloua El Messaoudi, Willem J M Mulder, Mihai G Netea, George M Slavich, Niels P Riksen

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  • A four-dimensional framework for classifying functional states in immune cells.

    iScience

    Authors: Rachel Brandes-Leibovitz, Gal Yankovitz, Eran Bacharach, Mihai G Netea, Evangelos J Giamarellos-Bourboulis, Irit Gat-Viks

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