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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Mihai Netea

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Recent publications

  • Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra- IL-1R immune evasion strategies of emerging fungal pathogen Candida auris.

    PLoS pathogens

    Authors: Abishek Balakumar, Diprasom Das, Abhishek Datta, Abtar Mishra, Garrett Bryak, Shrihari M Ganesh, Mihai G Netea, Vinod Kumar, Michail S Lionakis, Devender Arora, Jyothi Thimmapuram, Shankar Thangamani

  • Interleukin-10 inhibits important components of trained immunity in human monocytes.

    Journal of leukocyte biology

    Authors: Rutger J Röring, Flavia Scognamiglio, Lisanne C de Jong, Laszlo A Groh, Vasiliki Matzaraki, Valerie A C M Koeken, Leo A B Joosten, Athanasios Ziogas, Mihai G Netea

  • Trained immunity in the bone marrow: Hub of autoimmunity.

    Cell stem cell

    Authors: Mihai G Netea, Leo A B Joosten

All publications by Prof. Dr. Mihai Netea