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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • Functional and transcriptional senescence profiles of CD8+ T cells associate with the presence of carotid plaques in people living with HIV.

    The Journal of infectious diseases

    Authors: Marc J T Blaauw, Adriana Navas, Victoria Rios Vásquez, Nadira Vadaq, Marvin A H Berrevoets, Twan Otten, Wilhelm A J W Vos, Louise E van Eekeren, Albert L Groenendijk, Gert Weijers, Esther Lutgens, Hans J P M Koenen, Marien I de Jonge, Mihai G Netea, Joost H W Rutten, Andre J A M van der Ven, Niels P Riksen

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  • Sudan's complex genetic admixture history drives adaptation to malaria in Sudanese Copts.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Laura Vilà-Valls, Jorge Garcia-Calleja, Javier Prado-Martinez, Elena Bosch, Aida M Andrés, Mihai G Netea, David Comas, Hisham Y Hassan

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  • A randomized controlled trial of precision bezlotoxumab treatment for Clostridioides difficile infection.

    Cell reports. Medicine

    Authors: Christos Psarrakis, Nikolaos-Renatos Tziolos, Vicky Matzarakis, Vinod Kumar, Emmanouil Stylianakis, Chrysanthi Sidiropoulou, Elisavet Tasouli, Konstantina Iliopoulou, Michael Samarkos, Symeon Metallidis, Sarah Georgiadou, Karolina Akinosoglou, Amalia Bolanou, Erifli Hatziagelaki, Alina Kostaki, Periklis Panagopoulos, Konstantinos Toutouzas, Haralarampos Milionis, Georgios Adamis, Garyfallia Poulakou, Malvina Lada, Athanasios Skoutelis, Zoi Alexiou, Styliani Symbardi, George Chrysos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

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