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Prof. Dr. Mihai Netea

Member, Steering-Committee Member

Life & Medical Sciences Institute (LIMES)

University of Bonn Carl-Troll-Strasse 31 53115 Bonn

mnetea@uni-bonn.de

+31 24 361 8819

Website

The goal of my research efforts is to translate information obtained through the assessment of human genetic variation in patients into novel diagnostic and therapeutic approaches. My group has a strong track record on translating genetic information into understanding pathophysiological mechanisms of disease. I have a broad expertise on the host mechanisms responsible for the recognition of bacterial and fungal pathogens and the activation of the innate immune system, on the one hand, and the genetic susceptibility to infections on the other hand. I have described the epigenetic mechanisms mediating innate immune memory (‘trained immunity’) for the first time.

Recent publications

  • Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen.

    eLife

    Authors: Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

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  • Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV.

    Aging cell

    Authors: Adriana Navas, Vasiliki Matzaraki, Louise E van Eekeren, Marc J T Blaauw, Albert L Groenendijk, Wilhelm A J W Vos, Maartje Jacobs-Cleophas, Jéssica C Dos Santos, André J A M van der Ven, Leo A B Joosten, Mihai G Netea

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  • Host-Directed Therapy in Pandemic Preparedness.

    JAMA

    Authors: Mihai G Netea, Frank L van de Veerdonk, Evangelos J Giamarellos-Bourboulis

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