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Prof. Dr. Monique Breteler

Member, Steering-Committee Member

German Center for Neurodegenerative Diseases (DZNE)

Sigmund-Freud-Str. 27 53127 Bonn

monique.breteler@dzne.de

+49 228 43302929

Website

Our research uses an epidemiological approach to investigating the fundamentals of healthy aging and the chang-es that take place in the brain during the course of our lives. Using large-scale population-imaging studies, we study the role of vascular mechanisms, metabolic disorders, inflammation and lifestyle factors in the development and progression of neurodegenerative diseases, with a focus on early identification and prevention of disease.

Recent publications

  • Association analysis between an epigenetic alcohol risk score and blood pressure.

    Clinical epigenetics

    Authors: Helena Bui, Amena Keshawarz, Mengyao Wang, Mikyeong Lee, Scott M Ratliff, Lisha Lin, Kira S Birditt, Jessica D Faul, Annette Peters, Christian Gieger, Thomas Delerue, Sharon L R Kardia, Wei Zhao, Xiuqing Guo, Jie Yao, Jerome I Rotter, Yi Li, Xue Liu, Dan Liu, Juliana F Tavares, Gökhan Pehlivan, Monique M B Breteler, Irma Karabegovic, Carolina Ochoa-Rosales, Trudy Voortman, Mohsen Ghanbari, Joyce B J van Meurs, Mohamed Kamal Nasr, Marcus Dörr, Hans J Grabe, Stephanie J London, Alexander Teumer, Melanie Waldenberger, David R Weir, Jennifer A Smith, Daniel Levy, Jiantao Ma, Chunyu Liu

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  • Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration.

    Communications biology

    Authors: Shahzad Ahmad, Mohammad Aslam Imtiaz, Aniket Mishra, Ruiqi Wang, Marisol Herrera-Rivero, Joshua C Bis, Myriam Fornage, Gennady Roshchupkin, Edith Hofer, Mark Logue, W T Longstreth, Rui Xia, Vincent Bouteloup, Thomas Mosley, Lenore J Launer, Michael Khalil, Jens Kuhle, Robert A Rissman, Genevieve Chene, Carole Dufouil, Luc Djoussé, Michael J Lyons, Kenneth J Mukamal, William S Kremen, Carol E Franz, Reinhold Schmidt, Stephanie Debette, Monique M B Breteler, Klaus Berger, Qiong Yang, Sudha Seshadri, N Ahmad Aziz, Mohsen Ghanbari, M Arfan Ikram

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  • Blood-derived microRNAs are related to cognitive domains in the general population.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Konstantinos Melas, Valentina Talevi, Mohammed Aslam Imtiaz, Rika Etteldorf, Santiago Estrada, Dennis M Krüger, Tonatiuh Pena-Centeno, N Ahmad Aziz, André Fischer, Monique M B Breteler

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