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Prof. Dr. Özgün Gökce

Member

Medical Faculty, University of Bonn & German Center for Neurodegenerative Diseases (DZNE)

Venusberg-Campus 1/99 D-53127 Bonn Germany

Ozgun.Goekce@ukbonn.de

Website

Our research group represents a synergistic fusion of multi disciplinary expertise, striving to unravel the complexities of age-related brain disorders through the development of cutting-edge quantitative genomics techniques. Our mission is to decode the cellular responses underlying the aging process and to dissect the molecular mechanisms driving neurodevelopmental and neurodegenerative disorders. To achieve these objectives, we develop and integrate state-of-the-art technologies, including single-cell RNA sequencing (scRNA-seq), spatial transcriptomics (ST), electron microscopy, and machine learning algorithms, forging a comprehensive and holistic understanding of these critical biological processes.

Ozgun Gokce

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Recent publications

  • Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.

    Nature communications

    Authors: Ali Rezaei, Virág Kocsis-Jutka, Zeynep I Gunes, Qing Zeng, Georg Kislinger, Franz Bauernschmitt, Huseyin Berkcan Isilgan, Laura R Parisi, Tuğberk Kaya, Sören Franzenburg, Jonas Koppenbrink, Julia Knogler, Thomas Arzberger, Daniel Farny, Brigitte Nuscher, Eszter Katona, Ashutosh Dhingra, Chao Yang, Garyfallia Gouna, Katherine D LaClair, Aleksandar Janjic, Wolfgang Enard, Qihui Zhou, Nellwyn Hagan, Dimitry Ofengeim, Eduardo Beltrán, Ozgun Gokce, Mikael Simons, Sabine Liebscher, Dieter Edbauer

  • An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis.

    Nature communications

    Authors: Omar El Bounkari, Chunfang Zan, Bishan Yang, Simon Ebert, Jonas Wagner, Elina Bugar, Naomi Kramer, Priscila Bourilhon, Christos Kontos, Marlies Zarwel, Dzmitry Sinitski, Jelena Milic, Yvonne Jansen, Wolfgang E Kempf, Nadja Sachs, Lars Maegdefessel, Hao Ji, Ozgun Gokce, Fabien Riols, Mark Haid, Simona Gerra, Adrian Hoffmann, Markus Brandhofer, Maida Avdic, Richard Bucala, Remco T A Megens, Nienke Willemsen, Denise Messerer, Christian Schulz, Alexander Bartelt, Tobias Harm, Dominik Rath, Yvonne Döring, Meinrad Gawaz, Christian Weber, Aphrodite Kapurniotu, Jürgen Bernhagen

  • Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.

    Nature neuroscience

    Authors: Boyan Bonev, Gonçalo Castelo-Branco, Fei Chen, Simone Codeluppi, M Ryan Corces, Jean Fan, Myriam Heiman, Kenneth Harris, Fumitaka Inoue, Manolis Kellis, Ariel Levine, Mo Lotfollahi, Chongyuan Luo, Kristen R Maynard, Mor Nitzan, Vijay Ramani, Rahul Satijia, Lucas Schirmer, Yin Shen, Na Sun, Gilad S Green, Fabian Theis, Xiao Wang, Joshua D Welch, Ozgun Gokce, Genevieve Konopka, Shane Liddelow, Evan Macosko, Omer Ali Bayraktar, Naomi Habib, Tomasz J Nowakowski

All publications by Prof. Dr. Özgün Gökce