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Prof. Dr. Özgün Gökce

Member

Medical Faculty, University of Bonn & German Center for Neurodegenerative Diseases (DZNE)

Venusberg-Campus 1/99 D-53127 Bonn Germany

Ozgun.Goekce@ukbonn.de

Website

Our research group represents a synergistic fusion of multi disciplinary expertise, striving to unravel the complexities of age-related brain disorders through the development of cutting-edge quantitative genomics techniques. Our mission is to decode the cellular responses underlying the aging process and to dissect the molecular mechanisms driving neurodevelopmental and neurodegenerative disorders. To achieve these objectives, we develop and integrate state-of-the-art technologies, including single-cell RNA sequencing (scRNA-seq), spatial transcriptomics (ST), electron microscopy, and machine learning algorithms, forging a comprehensive and holistic understanding of these critical biological processes.

Ozgun Gokce

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Recent publications

  • Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system.

    Nature neuroscience

    Authors: Igor Adameyko, Trygve Bakken, Aparna Bhaduri, Chintan Chhatbar, Mariella G Filbin, David Gate, Hannah Hochgerner, Chang Nam Kim, Jordan Krull, Gioele La Manno, Qingyun Li, Sten Linnarsson, Qin Ma, Christian Mayer, Vilas Menon, Patricia Nano, Marco Prinz, Steve Quake, Christopher A Walsh, Jin Yang, Omer Ali Bayraktar, Ozgun Gokce, Naomi Habib, Genevieve Konopka, Shane A Liddelow, Tomasz J Nowakowski

  • Implementation and validation of single-cell genomics experiments in neuroscience.

    Nature neuroscience

    Authors: Marco Colonna, Genevieve Konopka, Shane A Liddelow, Tomasz Nowakowski, Rajeshwar Awatramani, Helen S Bateup, Cathryn R Cadwell, Emre Caglayan, Jerry L Chen, Jesse Gillis, Martin Kampmann, Fenna Krienen, Samuel E Marsh, Michelle Monje, Michael R O'Dea, Rickie Patani, Alex A Pollen, Francisco J Quintana, Marissa Scavuzzo, Matthew Schmitz, Steven A Sloan, Paul J Tesar, Jessica Tollkuhn, Maria Antonietta Tosches, Madeleine E Urbanek, Jonathan M Werner, Omer A Bayraktar, Ozgun Gokce, Naomi Habib

  • Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.

    Nature neuroscience

    Authors: Boyan Bonev, Castelo-Branco Gonçalo, Fei Chen, Simone Codeluppi, M Ryan Corces, Jean Fan, Myriam Heiman, Kenneth Harris, Fumitaka Inoue, Manolis Kellis, Ariel Levine, Mo Lotfollahi, Chongyuan Luo, Kristen R Maynard, Mor Nitzan, Vijay Ramani, Rahul Satijia, Lucas Schirmer, Yin Shen, Na Sun, Gilad S Green, Fabian Theis, Xiao Wang, Joshua D Welch, Ozgun Gokce, Genevieve Konopka, Shane Liddelow, Evan Macosko, Omer Bayraktar, Naomi Habib, Tomasz J Nowakowski

All publications by Prof. Dr. Özgün Gökce