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Dr. Tal Pecht

Member

German Center for Neurodegenerative Diseases (DZNE)

Room Nr. B.3.011-030 (DZNE), Venusberg-Campus 1, 53127 Bonn

tpecht@uni-bonn.de

+49 228 43302707

While systems immunology has advanced, understanding the healthy female immune system remains incomplete. The FemmunityX research team focuses on the variation of the female immune system in health and disease, aiming to understand its role in immune sex differences. The interaction between the immune and endocrine systems is particularly dynamic in metabolic conditions like obesity and insulin resistance. We hypothesize that these changes create a dynamic range of immune-sex differences. Our goal is to investigate how endocrine and metabolic fluctuations shape the female immune system and contribute to immune sex differences. Using systems biology, we study immune-metabolic sex differences in various populations, including collaborations in Tanzania and Bonn. Using advanced bioinformatics to characterize the female immune-metabolic systems, we analyze transcriptome, metabolome, and proteome data.

Dr. Tal Pecht

Recent publications

  • Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial.

    Nature medicine

    Authors: Godfrey S Temba, Tal Pecht, Vesla I Kullaya, Nadira Vadaq, Mary V Mosha, Thomas Ulas, Sneha Kanungo, Liesbeth van Emst, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Elias Mafuru, Paolo Lionetti, Musa M Mhlanga, Andre J van der Ven, Duccio Cavalieri, Leo A B Joosten, Reginald A Kavishe, Blandina T Mmbaga, Joachim L Schultze, Mihai G Netea, Quirijn de Mast

  • Unveiling the power of high-dimensional cytometry data with cyCONDOR.

    Nature communications

    Authors: Charlotte Kröger, Sophie Müller, Jacqueline Leidner, Theresa Kröber, Stefanie Warnat-Herresthal, Jannis Bastian Spintge, Timo Zajac, Anna Neubauer, Aleksej Frolov, Caterina Carraro, Frank Jessen, Simone Puccio, Anna C Aschenbrenner, Joachim L Schultze, Tal Pecht, Marc D Beyer, Lorenzo Bonaguro

All publications by Dr. Tal Pecht