Success in the "Advanced Clinician Scientist" proposal
—The Medical Faculty of the University of Bonn and the University Hospital Bonn (UKB) will be in the next five years part of the tender "Advanced Clinician Scientist" (ACS) of the Federal Ministry of Education and Research (BMBF) in the areas of immunopathogenesis and organ dysfunction as well as brain and neurodegeneration. The Medical Faculty and the UKB will receive around 9,000,000 euros for the project, with which the Advanced Clinician Scientist Program Bonn will be set up.
—Urban Tanzanians have a more activated immune system compared to their rural counterparts. The difference in diet appears to explain this difference: in the cities, people eat a more western style diet, while in rural areas a traditional diet is more common.
—The course for organ health is set in the early embryo. For this finding, Prof. Elvira Mass, a scientist from the Cluster of Excellence ImmunoSensation, receives the Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers, which is endowed with 60,000 euros. In her research, she showed that specialized immune cells from the yolk sac accompany organ development and contribute to maintaining their health throughout life.
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ImmunoSensation scientist discover differences in fat metabolism
—Coconut oil has increasingly found its way into German kitchens in recent years, although its alleged health benefits are controversial. Scientists at the University of Bonn from the Cluster of Excellence ImmunoSensation have now been able to show how it is metabolized in the liver. Their findings could also have implications for the treatment of certain diarrheal diseases. The results are published in the journal Molecular Metabolism.
School Project about Healthy Food and the Immune System
—Junior researchers Dr. Anette Christ and Dr. Elisabeth Jurack at the University of Bonn receive 10,000 euros from the BMBF and "Wissenschaft im Dialog" for their Podcast: How do we eat in the 21st century?
Bonn schoolchildren will soon be able to deal with this question together with scientists in a podcast. The biologists from the Cluster of Excellence impressed with their communication idea in the Germany-wide university competition.
—Filariae, slender but sometimes up to 70 centimeters long nematodes, can set up residence in their host quite tenaciously and cause serious infectious diseases in the tropics. The tiny larvae of the worms are usually transmitted from person to person by mosquitoes, which pick up the larvae from the blood or subcutaneous tissue when they bite and deposit them in the vessels or tissues of their next victim.
—ImmunoSensation scientists present latest findings on the coronavirus in "Genome Medicine"
According to current studies, the COVID-19 disease which is caused by the SARS-CoV-2 coronavirus comprises at least five different variants. These differ in how the immune system responds to the infection. Researchers from the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, together with other experts from Germany, Greece and the Netherlands, present these findings in Genome Medicine
—Nanobodies are much smaller than the classic antibodies used to treat SARS-CoV-2 infections, for example. They therefore penetrate the tissue better and can be produced more easily in larger quantities. The researchers at the University Hospital Bonn have also combined the nanobodies into potentially particularly effective molecules.
—The group from Peter Krawitz, member of the Cluster of Excellence ImmunoSensation create an animal model for studying GPI anchor deficiencies. Impaired intelligence, movement disorders and developmental delays are typical for a group of rare diseases that belong to GPI anchor deficiencies. Researchers from the University of Bonn and the Max Planck Institute for Molecular Genetics used genetic engineering methods to create a mouse that mimics these patients very well. Studies in this animal model suggest that in GPI anchor…
