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ATAC-ing human tissue Treg cells.

Immunity

Authors: Maren Köhne, Marc Beyer

What defines regulatory T (Treg) cells in healthy human tissues? In this issue of Immunity, Delacher et al. describe a human follicular helper T cell-like tissue-repair Treg cell signature governed by BATF based on chromatin accessibility data and link this on a transcriptome and protein level to important functional features like CCR8 expression.

Copyright © 2021 Elsevier Inc. All rights reserved.

PMID: 33852825

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