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Bacterial translocation promotes trained immunity.

Immunity

Authors: Maria Francesca Viola, Elvira Mass

Can bacteria that breach mucosal barriers drive long-lasting changes in immunity? In this issue of Immunity, Robles-Vera et al. describe how, in the context of colitis, bacteria breaching the intestinal barrier reprogram precursors in the bone marrow via Mincle-dependent signaling.

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PMID: 39938478

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