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Come together, right now! ZCCHC3 orchestrates cytosolic nucleic acid sensing through phase condensation.

Molecular cell

Authors: Rebecca Barker, Eva Bartok

In this issue of Molecular Cell, Shi et al. elucidate a novel role of host factor ZCCHC3 in positively regulating RLR and cGAS signaling through the binding of nucleic acids and induction of liquid phase condensation.

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PMID: 40054441

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