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Delayed Gastric Emptying Does Not Influence Cancer-Specific Survival after Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma.

Journal of clinical medicine

Authors: Christiane Pillny, Jessica Teschke, Jana Enderes, Steffen Manekeller, Jörg C Kalff, Tim R Glowka

BACKGROUND: Delayed gastric emptying (DGE) remains the most frequent complication following pancreatoduodenectomy (PD). The present study investigates the influence of delayed gastric emptying on cancer-specific survival after PD.

METHODS: We included 267 patients who underwent PD between 2014 and 2021. They were analyzed regarding demographic factors, pre- and perioperative characteristics, surgical complications, and long-term survival.

RESULTS: Patients with a higher Charlson Comorbidity Index (CCI) or pre-existing pulmonary disease suffered significantly more from DGE. When experiencing PPH, a prolonged hospital stay, or major overall complications (Clavien-Dindo °III-V) were more common in the DGE group. Tumor size over 3 cm negatively affected survival.

CONCLUSIONS: DGE has no influence on long-term survival in PDAC patients, although it prolongs hospital stay.

PMID: 35887964

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