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Increased innate immune responses in adolescents with obesity and its relation to subclinical cardiovascular measures: An exploratory study.

iScience

Authors: Siroon Bekkering, Christoph Saner, Boris Novakovic, Toby Mansell, Danielle K Longmore, Zoe McCallum, Anne-Louise Ponsonby, Markus Juonala, Mihai G Netea, Matthew A Sabin, Richard Saffery, Niels P Riksen, David P Burgner

Cardiometabolic risk accrues across the life course and childhood and adolescence are key periods for effective prevention. Obesity is associated with inflammation in adults, but pediatric data are scarce. In a cross-sectional and longitudinal study, we investigated immune cell composition and activation in 31 adolescents with obesity (41.9% male, BMIz>2.5, 14.4 years) and 22 controls with healthy weight (45.1% male, -1.5

© 2024 The Author(s).

PMID: 38741712

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