Manual vs automated Ga-radiolabelling-A comparison of optimized processes.

A critical factor for clinical practice is the production of Ga radiopharmaceuticals manufactured manually or through an automated procedure. Ga radiopharmaceuticals are often prepared manually, although this method can lead to an increased operator's radiation dose and potential variability within production. The present work compares Ga-radiolabelling (PSMA-11; DOTA-TOC) utilizing a cassette module (GAIA; Elysia-Raytest; Germany) with a manual setup for routine clinical production with regard to process reliability and reproducibility.

© 2019 The Authors. Journal of Labelled Compounds and Radiopharmaceuticals published by John Wiley & Sons Ltd.

PMID: 31845408