Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
Journal of hepatology
Authors:
Elena Kotsiliti, Valentina Leone, Svenja Schuehle, Olivier Govaere, Hai Li, Monika J Wolf, Helena Horvatic, Sandra Bierwirth, Jana Hundertmark, Donato Inverso, Laimdota Zizmare, Avital Sarusi-Portuguez, Revant Gupta, Tracy O'Connor, Anastasios D Giannou, Ahmad Mustafa Shiri, Yehuda Schlesinger, Maria Garcia Beccaria, Charlotte Rennert, Dominik Pfister, Rupert Öllinger, Iana Gadjalova, Pierluigi Ramadori, Mohammad Rahbari, Nuh Rahbari, Marc E Healy, Mirian Fernández-Vaquero, Neda Yahoo, Jakob Janzen, Indrabahadur Singh, Chaofan Fan, Xinyuan Liu, Monika Rau, Martin Feuchtenberger, Eva Schwaneck, Sebastian J Wallace, Simon Cockell, John Wilson-Kanamori, Prakash Ramachandran, Celia Kho, Timothy J Kendall, Anne-Laure Leblond, Selina J Keppler, Piotr Bielecki, Katja Steiger, Maike Hofmann, Karsten Rippe, Horst Zitzelsberger, Achim Weber, Nisar Malek, Tom Luedde, Mihael Vucur, Hellmut G Augustin, Richard Flavell, Oren Parnas, Roland Rad, Olivier Pabst, Neil C Henderson, Samuel Huber, Andrew Macpherson, Percy Knolle, Manfred Claassen, Andreas Geier, Christoph Trautwein, Kristian Unger, Eran Elinav, Ari Waisman, Zeinab Abdullah, Dirk Haller, Frank Tacke, Quentin M Anstee, Mathias Heikenwalder
Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC).
BMC cancer
Authors:
Linde Kehmann, Marie-Luise Berres, Maria Gonzalez-Carmona, Dominik P Modest, Raphael Mohr, Alexander Wree, Marino Venerito, Christian Strassburg, Verena Keitel, Christian Trautwein, Tom Luedde, Christoph Roderburg
Authors:
Esther Aix, Alex Gallinat, Carla Yago-Díez, Javier Lucas, Manuel José Gómez, Alberto Benguría, Patricia Freitag, Elizabeth Cortez-Toledo, Laura Fernández de Manuel, Lucía García-Cuasimodo, Héctor Sánchez-Iranzo, María C Montoya, Ana Dopazo, Fátima Sánchez-Cabo, Nadia Mercader, Javier E López, Bernd K Fleischmann, Michael Hesse, Ignacio Flores
Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.
Nature immunology
Authors:
Alyssa Silva-Cayetano, Sigrid Fra-Bido, Philippe A Robert, Silvia Innocentin, Alice R Burton, Emily M Watson, Jia Le Lee, Louise M C Webb, William S Foster, Ross C J McKenzie, Alexandre Bignon, Ine Vanderleyden, Dominik Alterauge, Julia P Lemos, Edward J Carr, Danika L Hill, Isabella Cinti, Karl Balabanian, Dirk Baumjohann, Marion Espeli, Michael Meyer-Hermann, Alice E Denton, Michelle A Linterman
Test-retest repeatability of organ uptake on PSMA-targeted F-DCFPyL PET/CT in patients with prostate cancer.
The Prostate
Authors:
Rudolf A Werner, Susanne Lütje, Bilêl Habacha, Lena Bundschuh, Takahiro Higuchi, Andreas K Buck, Aleksander Kosmala, Constantin Lapa, Markus Essler, Martin A Lodge, Kenneth J Pienta, Mario A Eisenberger, Mark C Markowski, Michael A Gorin, Martin G Pomper, Steven P Rowe, Ralph A Bundschuh
A randomized, open-label study of the tolerability and efficacy of one or three daily doses of ivermectin plus diethylcarbamazine and albendazole (IDA) versus one dose of ivermectin plus albendazole (IA) for treatment of onchocerciasis.
PLoS neglected tropical diseases
Authors:
Nicholas O Opoku, Felix Doe, Bettina Dubben, Nicole Fetcho, Kerstin Fischer, Peter U Fischer, Shelter Gordor, Charles W Goss, Michael E Gyasi, Achim Hoerauf, Augustine R Hong, Eric Kanza, Christopher L King, Ruth Laryea, Daphne Lew, Mahmood A Seidu, Gary J Weil
Evolution of age-related mutation-driven clonal haematopoiesis over 20 years is associated with metabolic dysfunction in obesity.
EBioMedicine
Authors:
Johanna C Andersson-Assarsson, Rosanne C van Deuren, Felipe M Kristensson, Marloes Steehouwer, Kajsa Sjöholm, Per-Arne Svensson, Marc Pieterse, Christian Gilissen, Magdalena Taube, Peter Jacobson, Rosie Perkins, Han G Brunner, Mihai G Netea, Markku Peltonen, Björn Carlsson, Alexander Hoischen, Lena M S Carlsson