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featured publications

  • Platelets Fuel the Inflammasome Activation of Innate Immune Cells.

    Cell reports

    Authors: Verena Rolfes, Lucas Secchim Ribeiro, Ibrahim Hawwari, Lisa Böttcher, Nathalia Rosero, Salie Maasewerd, Marina Lima Silva Santos, Tomasz Próchnicki, Camila Meirelles de Souza Silva, Carlos Wagner de Souza Wanderley, Maximilian Rothe, Susanne V Schmidt, H James Stunden, Damien Bertheloot, Magali Noval Rivas, Cor Jesus Fontes, Luzia Helena Carvalho, Fernando Queiroz Cunha, Eicke Latz, Moshe Arditi, Bernardo Simoes Franklin

  • β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia.

    Cell reports

    Authors: Lea L Friker, Hannah Scheiblich, Inga V Hochheiser, Rebecca Brinkschulte, Dietmar Riedel, Eicke Latz, Matthias Geyer, Michael T Heneka

  • PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment.

    Acta neuropathologica

    Authors: Luca Kleineidam, Vincent Chouraki, Tomasz Próchnicki, Sven J van der Lee, Laura Madrid-Márquez, Holger Wagner-Thelen, Ilker Karaca, Leonie Weinhold, Steffen Wolfsgruber, Anne Boland, Pamela V Martino Adami, Piotr Lewczuk, Julius Popp, Frederic Brosseron, Iris E Jansen, Marc Hulsman, Johannes Kornhuber, Oliver Peters, Claudine Berr, Reinhard Heun, Lutz Frölich, Christophe Tzourio, Jean-François Dartigues, Michael Hüll, Ana Espinosa, Isabel Hernández, Itziar de Rojas, Adelina Orellana, Sergi Valero, Najada Stringa, Natasja M van Schoor, Martijn Huisman, Philip Scheltens, Eckart Rüther, Jean-Francois Deleuze, Jens Wiltfang, Lluis Tarraga, Matthias Schmid, Martin Scherer, Steffi Riedel-Heller, Michael T Heneka, Philippe Amouyel, Frank Jessen, Merce Boada, Wolfgang Maier, Anja Schneider, Antonio González-Pérez, Wiesje M van der Flier, Michael Wagner, Jean-Charles Lambert, Henne Holstege, Mª Eugenia Sáez, Eicke Latz, Agustin Ruiz, Alfredo Ramirez

  • Defining trained immunity and its role in health and disease.

    Nature reviews. Immunology

    Authors: Mihai G Netea, Jorge Domínguez-Andrés, Luis B Barreiro, Triantafyllos Chavakis, Maziar Divangahi, Elaine Fuchs, Leo A B Joosten, Jos W M van der Meer, Musa M Mhlanga, Willem J M Mulder, Niels P Riksen, Andreas Schlitzer, Joachim L Schultze, Christine Stabell Benn, Joseph C Sun, Ramnik J Xavier, Eicke Latz

  • Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Frederic Brosseron, Carl-Christian Kolbe, Francesco Santarelli, Stephanie Carvalho, Anna Antonell, Sergio Castro-Gomez, Pawel Tacik, Aishwarya Alex Namasivayam, Graziella Mangone, Reinhard Schneider, Eicke Latz, Ullrich Wüllner, Per Svenningsson, Raquel Sánchez-Valle, José Luis Molinuevo, Jean-Christophe Corvol, Michael T Heneka

  • Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.

    Immunity

    Authors: Mario A Lauterbach, Jasmin E Hanke, Magdalini Serefidou, Matthew S J Mangan, Carl-Christian Kolbe, Timo Hess, Maximilian Rothe, Romina Kaiser, Florian Hoss, Jan Gehlen, Gudrun Engels, Maike Kreutzenbeck, Susanne V Schmidt, Anette Christ, Axel Imhof, Karsten Hiller, Eicke Latz

  • Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.

    Nature immunology

    Authors: Stephen Zewinger, Jochen Reiser, Vera Jankowski, Dalia Alansary, Eunsil Hahm, Sarah Triem, Mira Klug, Stefan J Schunk, David Schmit, Rafael Kramann, Christina Körbel, Emmanuel Ampofo, Matthias W Laschke, Simina-Ramona Selejan, Anna Paschen, Tobias Herter, Susanne Schuster, Günther Silbernagel, Martina Sester, Urban Sester, Gunter Aßmann, Robert Bals, Gerhard Kostner, Willi Jahnen-Dechent, Michael D Menger, Lucia Rohrer, Winfried März, Michael Böhm, Joachim Jankowski, Manfred Kopf, Eicke Latz, Barbara A Niemeyer, Danilo Fliser, Ulrich Laufs, Thimoteus Speer

  • Top publication

    NLRP3 inflammasome activation drives tau pathology.

    Nature

    Authors: Christina Ising, Carmen Venegas, Shuangshuang Zhang, Hannah Scheiblich, Susanne V Schmidt, Ana Vieira-Saecker, Stephanie Schwartz, Shadi Albasset, Róisín M McManus, Dario Tejera, Angelika Griep, Francesco Santarelli, Frederic Brosseron, Sabine Opitz, James Stunden, Maximilian Merten, Rakez Kayed, Douglas T Golenbock, David Blum, Eicke Latz, Luc Buée, Michael T Heneka

  • Western Diet and the Immune System: An Inflammatory Connection.

    Immunity

    Authors: Anette Christ, Mario Lauterbach, Eicke Latz

  • CD82 controls CpG-dependent TLR9 signaling.

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Authors: Nida S Khan, Daniel P Lukason, Marianela Feliu, Rebecca A Ward, Allison K Lord, Jennifer L Reedy, Zaida G Ramirez-Ortiz, Jenny M Tam, Pia V Kasperkovitz, Paige E Negoro, Tammy D Vyas, Shuying Xu, Melanie M Brinkmann, Mridu Acharaya, Katerina Artavanis-Tsakonas, Eva-Maria Frickel, Christine E Becker, Zeina Dagher, You-Me Kim, Eicke Latz, Hidde L Ploegh, Michael K Mansour, Cindy K Miranti, Stuart M Levitz, Jatin M Vyas