Postoperative adjuvant radiochemotherapy with cisplatin versus adjuvant radiochemotherapy with cisplatin and pembrolizumab in locally advanced head and neck squamous cell carcinoma- the study protocol of the Adrisk trial.
Frontiers in oncology
Authors:
Susanne Wiegand, Gunnar Wichmann, Jeannette Vogt, Kathrin Vogel, Annegret Franke, Thomas Kuhnt, Florian Lordick, Anne-Marie Scheuble, Peter Hambsch, Peter Brossart, Franz Georg Bauernfeind, Holger Kaftan, Georg Maschmeyer, Matthias Paland, Marc Münter, Victor Lewitzki, Nicole Rotter, Carmen Stromberger, Marcus Beck, Steffen Dommerich, Thomas Christoph Gauler, Gunnar Hapke, Orlando Guntinas-Lichius, Ursula Schröder, Martin Görner, Matthias G Hautmann, Felix Steger, Bálint Tamaskovics, Anett Schmiedeknecht, Andreas Dietz
Mitochondrial damage activates the NLRP10 inflammasome.
Nature immunology
Authors:
Tomasz Próchnicki, Matilde B Vasconcelos, Kim S Robinson, Matthew S J Mangan, Dennis De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A Kufer, Florian I Schmidt, Franklin L Zhong, Eicke Latz
Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation.
Nature immunology
Authors:
Danping Zheng, Gayatree Mohapatra, Lara Kern, Yiming He, Merav D Shmueli, Rafael Valdés-Mas, Aleksandra A Kolodziejczyk, Tomasz Próchnicki, Matilde B Vasconcelos, Lena Schorr, Franziska Hertel, Ye Seul Lee, Miguel Camacho Rufino, Emmanuelle Ceddaha, Sandy Shimshy, Ryan James Hodgetts, Mally Dori-Bachash, Christian Kleimeyer, Kim Goldenberg, Melina Heinemann, Noa Stettner, Alon Harmelin, Hagit Shapiro, Jens Puschhof, Minhu Chen, Richard A Flavell, Eicke Latz, Yifat Merbl, Suhaib K Abdeen, Eran Elinav
Perioperative therapy with FLOT4 significantly increases survival in patients with gastroesophageal and gastric cancer in a large real-world cohort.
International journal of cancer
Authors:
Christian Möhring, Adrianna Mańczak, Aliki Timotheou, Farsaneh Sadeghlar, Taotao Zhou, Robert Mahn, Malte B Monin, Marieta Toma, Georg Feldmann, Peter Brossart, Mümtaz Köksal, Gustavo R Sarria, Nils Sommer, Philipp Lingohr, Azin Jafari, Jörg C Kalff, Christian P Strassburg, Maria A Gonzalez-Carmona
CD4 T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.
Science translational medicine
Authors:
Hans-Joachim Paust, Ning Song, Donatella De Feo, Nariaki Asada, Selma Tuzlak, Yu Zhao, Jan-Hendrik Riedel, Malte Hellmig, Amirrtavarshni Sivayoganathan, Anett Peters, Anna Kaffke, Alina Borchers, Ulrich O Wenzel, Oliver M Steinmetz, Gisa Tiegs, Elisabeth Meister, Matthias Mack, Christian Kurts, Sibylle von Vietinghoff, Maja T Lindenmeyer, Elion Hoxha, Rolf A K Stahl, Tobias B Huber, Stefan Bonn, Catherine Meyer-Schwesinger, Thorsten Wiech, Jan-Eric Turner, Burkhard Becher, Christian F Krebs, Ulf Panzer