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featured publications

  • An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis.

    PLoS pathogens

    Authors: Jula Reuter, Christian Otten, Nicolas Jacquier, Junghoon Lee, Dominique Mengin-Lecreulx, Iris Löckener, Robert Kluj, Christoph Mayer, Federico Corona, Julia Dannenberg, Sébastien Aeby, Henrike Bühl, Gilbert Greub, Waldemar Vollmer, Scot P Ouellette, Tanja Schneider, Beate Henrichfreise

  • Bacillus Calmette-Guérin vaccine for prevention of COVID-19 and other respiratory tract infections in older adults with comorbidities: a randomized controlled trial.

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    Authors: Eva L Koekenbier, Konstantin Fohse, Josephine S van de Maat, Jan Jelrik Oosterheert, Cees van Nieuwkoop, Jacobien J Hoogerwerf, Martin P Grobusch, Maurice A A J van den Bosch, Janneke H H van de Wijgert, Mihai G Netea, Frits R Rosendaal, Marc J M Bonten, C H Henri van Werkhoven

  • Histopathological evaluation of nodules by microscopy and by digital image analysis for the study of macrofilaricidal drug efficacy.

    Frontiers in medicine

    Authors: Kerstin Fischer, Bettina Dubben, Linda B Debrah, Janina M Kuehlwein, Arcangelo Ricchiuto, Alexander Y Debrah, Achim Hoerauf, Gary J Weil, Peter U Fischer, Ute Klarmann-Schulz

  • Agonistic and antagonistic targeting of immune checkpoint molecules differentially regulate osteoclastogenesis.

    Frontiers in immunology

    Authors: Victoria C Brom, Andreas C Strauss, Alexander Sieberath, Jochen Salber, Christof Burger, Dieter C Wirtz, Frank A Schildberg

  • DNA methylation of GITR, OX40, 4-1BB, CD27 , and CD40 correlates with BAP1 aberrancy and prognosis in uveal melanoma.

    Melanoma research

    Authors: Friederike Hoffmann, Anne Fröhlich, Judith Sirokay, Luka de Vos, Romina Zarbl, Jörn Dietrich, Sebastian Strieth, Jennifer Landsberg, Dimo Dietrich

  • RNA-DNA hybrids prevent resection at dysfunctional telomeres.

    Cell reports

    Authors: Vanessa Borges Pires, Nina Lohner, Tina Wagner, Carolin B Wagner, Maya Wilkens, Mona Hajikazemi, Katrin Paeschke, Falk Butter, Brian Luke

  • Toll-like receptor-3 contributes to the development of aortic valve stenosis.

    Basic research in cardiology

    Authors: Sven Thomas Niepmann, Nicola Willemsen, Ann Sophie Boucher, Marta Stei, Philip Goody, Andreas Zietzer, Marko Bulic, Hannah Billig, Alexandru Odainic, Christina Katharina Weisheit, Christine Quast, Matti Adam, Susanne V Schmidt, Farhad Bakhtiary, Felix Jansen, Georg Nickenig, Eike Latz, Sebastian Zimmer

  • Cytokine Hyperresponsiveness in Children With ETV6::RUNX1-positive Acute Lymphoblastic Leukemia After Challenge With Common Pathogens.

    HemaSphere

    Authors: Nadine Rüchel, Marina Oldenburg, Stefan Janssen, Aleksandra A Pandyra, Wei Liu, Eleni Vasileiou, Daniel Hein, Vera Helena Jepsen, Ute Fischer, Daniel Picard, Gesine Kögler, Julia Hauer, Franziska Auer, Angelina Beer, Ortwin Adams, Colin MacKenzie, Martin Jaeger, Mihai G Netea, Arndt Borkhardt, Katharina L Gössling

  • Cigarette smoke depletes alveolar macrophages and delays clearance of .

    American journal of physiology. Lung cellular and molecular physiology

    Authors: Markus Fleischmann, Andrew G Jarnicki, Andrew S Brown, Chao Yang, Gary P Anderson, Natalio Garbi, Elizabeth L Hartland, Ian R van Driel, Garrett Z Ng

  • The presence of cerebellar B cell aggregates is associated with a specific chemokine profile in the cerebrospinal fluid in a mouse model of multiple sclerosis.

    Journal of neuroinflammation

    Authors: Verena Schropp, Rittika Chunder, Barbara Dietel, Sabine Tacke, Stefanie Kuerten