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Publications

featured publications

  • Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome.

    The EMBO journal

    Authors: Dario Tejera, Dilek Mercan, Juan M Sanchez-Caro, Mor Hanan, David Greenberg, Hermona Soreq, Eicke Latz, Douglas Golenbock, Michael T Heneka

  • Blocking Inflammasome Activation Caused by β-Amyloid Peptide (Aβ) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic.

    ACS chemical neuroscience

    Authors: Maryam Aftabizadeh, Marianna Tatarek-Nossol, Erika Andreetto, Omar El Bounkari, Markus Kipp, Cordian Beyer, Eicke Latz, Jürgen Bernhagen, Aphrodite Kapurniotu

  • High-Density Lipoproteins Decrease Proinflammatory Activity and Modulate the Innate Immune Response.

    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research

    Authors: Natalia A Taborda, Yurany Blanquiceth, Silvio Urcuqui-Inchima, Eicke Latz, Juan C Hernandez

  • AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice.

    Scientific reports

    Authors: Kristof Johannes Hupa, Kathy Stein, Reiner Schneider, Mariola Lysson, Bianca Schneiker, Veit Hornung, Eicke Latz, Yoichiro Iwakura, Jörg C Kalff, Sven Wehner

  • Alternative splicing regulates stochastic NLRP3 activity.

    Nature communications

    Authors: Florian Hoss, James L Mueller, Francisca Rojas Ringeling, Juan F Rodriguez-Alcazar, Rebecca Brinkschulte, Gerald Seifert, Rainer Stahl, Lori Broderick, Chris D Putnam, Richard D Kolodner, Stefan Canzar, Matthias Geyer, Hal M Hoffman, Eicke Latz

  • NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells.

    International journal of nanomedicine

    Authors: Tianshu Li, Matthias Zehner, Jieyan He, Tomasz Próchnicki, Gabor Horvath, Eicke Latz, Sven Burgdorf, Shinji Takeoka

  • The Western lifestyle has lasting effects on metaflammation.

    Nature reviews. Immunology

    Authors: Anette Christ, Eicke Latz

  • Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency.

    Biochemistry and biophysics reports

    Authors: Jieyan He, Tianshu Li, Tomasz Próchnicki, Gabor Horvath, Eicke Latz, Shinji Takeoka

  • Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model.

    Scientific reports

    Authors: Laia Civit, Ioanna Theodorou, Franziska Frey, Holger Weber, Andreas Lingnau, Carsten Gröber, Michael Blank, Chloé Dambrune, James Stunden, Marc Beyer, Joachim Schultze, Eicke Latz, Frédéric Ducongé, Michael H G Kubbutat, Günter Mayer

  • Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells.

    Journal of molecular medicine (Berlin, Germany)

    Authors: Luping Wang, Sarah Schmidt, Petra P Larsen, Johanna H Meyer, William R Roush, Eicke Latz, Frank G Holz, Tim U Krohne