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  • Top publication

    Pyroptosis inhibiting nanobodies block Gasdermin D pore formation.

    Nature communications

    Authors: Anja Kopp, Gregor Hagelueken, Isabell Jamitzky, Jonas Moecking, Lisa D J Schiffelers, Florian I Schmidt, Matthias Geyer

  • Abelson Helper Integration Site 1 haplotypes and peripheral blood expression associates with lithium response and immunomodulation in bipolar patients.

    Psychopharmacology

    Authors: Kosma Sakrajda, Karolina Bilska, Piotr M Czerski, Beata Narożna, Monika Dmitrzak-Węglarz, Stefanie Heilmann-Heimbach, Felix F Brockschmidt, Stefan Herms, Markus M Nöthen, Sven Cichon, Barbara Więckowska, Janusz K Rybakowski, Joanna Pawlak, Aleksandra Szczepankiewicz

  • Cutting Edge: STING Induces ACLY Activation and Metabolic Adaptations in Human Macrophages through TBK1.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Maximilian Nickenig, Matthew S J Mangan, Hye Eun Lee, Konstantinos Symeonidis, Antonia Henne, Romina Kaiser, Eike Geißmar, Hendrikus Garritsen, Zeinab Abdullah, Karsten Hiller, Eicke Latz, Mario A Lauterbach

  • Safety of baricitinib for the treatment of atopic dermatitis over a median of 1.6 years and up to 3.9 years of treatment: an updated integrated analysis of eight clinical trials.

    The Journal of dermatological treatment

    Authors: Thomas Bieber, Norito Katoh, Eric L Simpson, Marjolein de Bruin-Weller, Diamant Thaçi, Antonio Torrelo, Angelina Sontag, Susanne Grond, Maher Issa, Xiaoyu Lu, Tracy Cardillo, Katrin Holzwarth, Jacob P Thyssen

  • Baricitinib provides rapid and sustained improvements in absolute EASI and SCORAD outcomes in adults with moderate-to-severe atopic dermatitis.

    The Journal of dermatological treatment

    Authors: Jacob P Thyssen, Thomas Bieber, C Elise Kleyn, Audrey Nosbaum, Susanne Grond, Helmut Petto, Elisabeth Riedl, Andreas Wollenberg

  • Treatment of acute myeloid leukaemia in older patients - scope of intensive therapy? - A retrospective analysis.

    Hematology (Amsterdam, Netherlands)

    Authors: Karin Mayer, Michael Serries, Corinna Hahn-Ast, Savita Bisht, Peter Brossart, Georg Feldmann

  • Decoding metabolic signatures in Alzheimer's disease: a mitochondrial perspective.

    Cell death discovery

    Authors: Daniele Bano, Dan Ehninger, Giacinto Bagetta

  • Conditional NKT Cell Depletion in Mice Reveals a Negative Feedback Loop That Regulates CTL Cross-Priming.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Christoph Heuser-Loy, Ann-Kathrin Baumgart, Carl-Philipp Hackstein, Christina J F Courrèges, Marie-Sophie Philipp, Christoph A Thaiss, Tristan Holland, César Evaristo, Natalio Garbi, Christian Kurts

  • Early combination therapy of COVID-19 in high-risk patients.

    Infection

    Authors: Hans Martin Orth, Charlotte Flasshove, Moritz Berger, Sandra Tessa Hattenhauer, Kaja D Biederbick, Rebekka Mispelbaum, Uwe Klein, Jannik Stemler, Matthis Fisahn, Anna D Doleschall, Ben-Niklas Baermann, Eva Koenigshausen, Olga Tselikmann, Alexander Killer, Clara de Angelis, Smaranda Gliga, Johannes Stegbauer, Nikolai Spuck, Gerda Silling, Jürgen K Rockstroh, Christian P Strassburg, Peter Brossart, Jens P Panse, Björn-Erik Ole Jensen, Tom Luedde, Christoph Boesecke, Annkristin Heine, Oliver A Cornely, Malte B Monin

  • BCG vaccination impacts the epigenetic landscape of progenitor cells in human bone marrow.

    bioRxiv : the preprint server for biology

    Authors: Sarah J Sun, Raúl Aguirre-Gamboa, L Charlotte J de Bree, Joaquin Sanz, Anne Dumaine, Leo A B Joosten, Maziar Divangahi, Mihai G Netea, Luis B Barreiro