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featured publications

  • Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.

    PLoS neglected tropical diseases

    Authors: Marc P Hübner, Coralie Martin, Sabine Specht, Marianne Koschel, Bettina Dubben, Stefan J Frohberger, Alexandra Ehrens, Martina Fendler, Dominique Struever, Edward Mitre, Nathaly Vallarino-Lhermitte, Suzanne Gokool, Sara Lustigman, Manfred Schneider, Simon Townson, Achim Hoerauf, Ivan Scandale

  • Neither black nor white: do altered intestinal microbiota reflect chronic liver disease severity?

    Gut

    Authors: Felix Goeser, Philipp Münch, Till Robin Lesker, Philipp Ludwig Lutz, Benjamin Krämer, Dominik J Kaczmarek, Claudia Finnemann, Hans Dieter Nischalke, Robert Geffers, Marijo Parcina, Alice McHardy, Christian Strassburg, Achim Hoerauf, Jacob Nattermann, Isabelle Bekeredjian-Ding, Ulrich Spengler

  • The Performance of a Dithiothreitol-Based Diagnostic System in Diagnosing Periprosthetic Joint Infection Compared to Sonication Fluid Cultures and Tissue Biopsies.

    Zeitschrift fur Orthopadie und Unfallchirurgie

    Authors: Thomas Martin Randau, Ernst Molitor, Frank Sebastian Fröschen, Achim Hörauf, Hendrik Kohlhof, Sebastian Scheidt, Sascha Gravius, Gunnar T Hischebeth

  • Macrophages Mediate Increased CD8 T Cell Inflammation During Weight Loss in Formerly Obese Mice.

    Frontiers in endocrinology

    Authors: Jayagopi Surendar, Indulekha Karunakaran, Stefan J Frohberger, Marianne Koschel, Achim Hoerauf, Marc P Hübner

  • Top publication

    Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2.

    Immunity

    Authors: Thomas Ostendorf, Thomas Zillinger, Katarzyna Andryka, Thais Marina Schlee-Guimaraes, Saskia Schmitz, Samira Marx, Kübra Bayrak, Rebecca Linke, Sarah Salgert, Julia Wegner, Tatjana Grasser, Sonja Bauersachs, Leon Soltesz, Marc P Hübner, Maximilian Nastaly, Christoph Coch, Matthias Kettwig, Ingo Roehl, Marco Henneke, Achim Hoerauf, Winfried Barchet, Jutta Gärtner, Martin Schlee, Gunther Hartmann, Eva Bartok

  • The design and development of a multicentric protocol to investigate the impact of adjunctive doxycycline on the management of peripheral lymphoedema caused by lymphatic filariasis and podoconiosis.

    Parasites & vectors

    Authors: John Horton, Ute Klarmann-Schulz, Mariana Stephens, Philip J Budge, Yaya Coulibaly, Alex Debrah, Linda Batsa Debrah, Suma Krishnasastry, Upendo Mwingira, Abdallah Ngenya, Samuel Wanji, Mirani Weerasooriya, Channa Yahathugoda, Inge Kroidl, Drew Deathe, Andrew Majewski, Sarah Sullivan, Charles Mackenzie, Thomas B Nutman, Joseph P Shott, Gary Weil, Eric Ottesen, Achim Hoerauf

  • S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis.

    PLoS neglected tropical diseases

    Authors: Stefan J Frohberger, Frederic Fercoq, Anna-Lena Neumann, Jayagopi Surendar, Wiebke Stamminger, Alexandra Ehrens, Indulekha Karunakaran, Estelle Remion, Thomas Vogl, Achim Hoerauf, Coralie Martin, Marc P Hübner

  • Comparison of immune responses to Loa loa stage-specific antigen extracts in Loa loa-exposed BALB/c mice upon clearance of infection.

    Parasites & vectors

    Authors: Valerine C Chunda, Manuel Ritter, Ayukenchengamba Bate, Narcisse V T Gandjui, Mathias E Esum, Fanny F Fombad, Abdel J Njouendou, Patrick W C Ndongmo, Mark J Taylor, Achim Hoerauf, Laura E Layland, Joseph D Turner, Samuel Wanji

  • In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis.

    PLoS neglected tropical diseases

    Authors: Alexandra Ehrens, Christopher S Lunde, Robert T Jacobs, Dominique Struever, Marianne Koschel, Stefan J Frohberger, Franziska Lenz, Martina Fendler, Joseph D Turner, Stephen A Ward, Mark J Taylor, Yvonne R Freund, Rianna Stefanakis, Eric Easom, Xianfeng Li, Jacob J Plattner, Achim Hoerauf, Marc P Hübner

  • Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs.

    ACS infectious diseases

    Authors: Tsutomu Akama, Yvonne R Freund, Pamela W Berry, David S Carter, Eric E Easom, Kurt Jarnagin, Christopher S Lunde, Jacob J Plattner, Fernando Rock, Rianna Stefanakis, Chelsea Fischer, Christina A Bulman, Kee Chong Lim, Brian M Suzuki, Nancy Tricoche, Abdelmoneim Mansour, Utami DiCosty, Scott McCall, Ben Carson, John W McCall, James McKerrow, Marc P Hübner, Sabine Specht, Achim Hoerauf, Sara Lustigman, Judy A Sakanari, Robert T Jacobs