Publications

The role of trained immunity in COVID-19: Lessons for the next pandemic.

14/06/2023 Cell host & microbe

Authors: Mihai G Netea, Athanasios Ziogas, Christine Stabell Benn, Evangelos J Giamarellos-Bourboulis, Leo A B Joosten, Moshe Arditi, Konstantin Chumakov, Reinout van Crevel, Robert Gallo, Peter Aaby, Jos W M van der Meer

T-SPOT.TB reactivity in Southern African children with and without in utero HIV exposure.

09/06/2023 Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Authors: Saori C Iwase, Paul T Edlefsen, Lynnette Bhebhe, Kessy Motsumi, Sikhulile Moyo, Anna-Ursula Happel, Danica Shao, Nicholas Mmasa, Sara Schenkel, Melanie A Gasper, Melanie Dubois, Megan A Files, Chetan Seshadri, Fergal Duffy, John Aitchison, Mihai G Netea, Jennifer Jao, Donald W Cameron, Clive M Gray, Heather B Jaspan, Kathleen M Powis

High-throughput proteomic analysis reveals systemic dysregulation in virally suppressed people living with HIV.

08/06/2023 JCI insight

Authors: Nadira Vadaq, Yue Zhang, Wilhelm Ajw Vos, Albert L Groenendijk, Martinus Jt Blaauw, Louise E van Eekeren, Maartje Jacobs-Cleophas, Lisa van de Wijer, Jéssica Cristina Dos Santos, Muhammad Hussein Gasem, Leo Ab Joosten, Mihai G Netea, Quirijn de Mast, Jingyuan Fu, André Jam van der Ven, Vasiliki Matzaraki

Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells.

08/06/2023 Nature biomedical engineering

Authors: David P Schrijver, Rutger J Röring, Jeroen Deckers, Anne de Dreu, Yohana C Toner, Geoffrey Prevot, Bram Priem, Jazz Munitz, Eveline G Nugraha, Yuri van Elsas, Anthony Azzun, Tom Anbergen, Laszlo A Groh, Anouk M D Becker, Carlos Pérez-Medina, Roderick S Oosterwijk, Boris Novakovic, Simone J C F M Moorlag, Aron Jansen, Peter Pickkers, Matthijs Kox, Thijs J Beldman, Ewelina Kluza, Mandy M T van Leent, Abraham J P Teunissen, Roy van der Meel, Zahi A Fayad, Leo A B Joosten, Edward A Fisher, Maarten Merkx, Mihai G Netea, Willem J M Mulder

Corrigendum: The impact of circadian rhythm on Bacillus Calmette-Guérin vaccination effects on SARS-CoV-2 infections.

24/05/2023 Frontiers in immunology

Authors: Konstantin Föhse, Esther J M Taks, Simone J C F M Moorlag, Marc J M Bonten, Reinout van Crevel, Jaap Ten Oever, Cornelis H van Werkhoven, Mihai G Netea, Josephine S van de Maat, Jacobien J Hoogerwerf

Evolution of age-related mutation-driven clonal haematopoiesis over 20 years is associated with metabolic dysfunction in obesity.

18/05/2023 EBioMedicine

Authors: Johanna C Andersson-Assarsson, Rosanne C van Deuren, Felipe M Kristensson, Marloes Steehouwer, Kajsa Sjöholm, Per-Arne Svensson, Marc Pieterse, Christian Gilissen, Magdalena Taube, Peter Jacobson, Rosie Perkins, Han G Brunner, Mihai G Netea, Markku Peltonen, Björn Carlsson, Alexander Hoischen, Lena M S Carlsson

Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization.

09/05/2023 International journal of molecular sciences

Authors: Esther Clavero, José Manuel Sanchez-Maldonado, Angelica Macauda, Rob Ter Horst, Belém Sampaio-Marques, Artur Jurczyszyn, Alyssa Clay-Gilmour, Angelika Stein, Michelle A T Hildebrandt, Niels Weinhold, Gabriele Buda, Ramón García-Sanz, Waldemar Tomczak, Ulla Vogel, Andrés Jerez, Daria Zawirska, Marzena Wątek, Jonathan N Hofmann, Stefano Landi, John J Spinelli, Aleksandra Butrym, Abhishek Kumar, Joaquín Martínez-López, Sara Galimberti, María Eugenia Sarasquete, Edyta Subocz, Elzbieta Iskierka-Jażdżewska, Graham G Giles, Malwina Rybicka-Ramos, Marcin Kruszewski, Niels Abildgaard, Francisco García Verdejo, Pedro Sánchez Rovira, Miguel Inacio da Silva Filho, Katalin Kadar, Małgorzata Razny, Wendy Cozen, Matteo Pelosini, Manuel Jurado, Parveen Bhatti, Marek Dudzinski, Agnieszka Druzd-Sitek, Enrico Orciuolo, Yang Li, Aaron D Norman, Jan Maciej Zaucha, Rui Manuel Reis, Miroslaw Markiewicz, Juan José Rodríguez Sevilla, Vibeke Andersen, Krzysztof Jamroziak, Kari Hemminki, Sonja I Berndt, Vicent Rajkumar, Grzegorz Mazur, Shaji K Kumar, Paula Ludovico, Arnon Nagler, Stephen J Chanock, Charles Dumontet, Mitchell J Machiela, Judit Varkonyi, Nicola J Camp, Elad Ziv, Annette Juul Vangsted, Elizabeth E Brown, Daniele Campa, Celine M Vachon, Mihai G Netea, Federico Canzian, Asta Försti, Juan Sainz

A single-cell view on host immune transcriptional response to in vivo BCG-induced trained immunity.

07/05/2023 Cell reports

Authors: Wenchao Li, Simone J C F M Moorlag, Valerie A C M Koeken, Rutger J Röring, L Charlotte J de Bree, Vera P Mourits, Manoj K Gupta, Bowen Zhang, Jianbo Fu, Zhenhua Zhang, Inge Grondman, Krista E van Meijgaarden, Liang Zhou, Ahmed Alaswad, Leo A B Joosten, Reinout van Crevel, Cheng-Jian Xu, Mihai G Netea, Yang Li

Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?

28/04/2023 International journal of molecular sciences

Authors: Antonio José Cabrera-Serrano, José Manuel Sánchez-Maldonado, Rob Ter Horst, Angelica Macauda, Paloma García-Martín, Yolanda Benavente, Stefano Landi, Alyssa Clay-Gilmour, Yasmeen Niazi, Blanca Espinet, Juan José Rodríguez-Sevilla, Eva María Pérez, Rossana Maffei, Gonzalo Blanco, Matteo Giaccherini, James R Cerhan, Roberto Marasca, Miguel Ángel López-Nevot, Tzu Chen-Liang, Hauke Thomsen, Irene Gámez, Daniele Campa, Víctor Moreno, Silvia de Sanjosé, Rafael Marcos-Gragera, María García-Álvarez, Trinidad Dierssen-Sotos, Andrés Jerez, Aleksandra Butrym, Aaron D Norman, Mario Luppi, Susan L Slager, Kari Hemminki, Yang Li, Sonja I Berndt, Delphine Casabonne, Miguel Alcoceba, Anna Puiggros, Mihai G Netea, Asta Försti, Federico Canzian, Juan Sainz

Randomized clinical trials of COVID-19 vaccines: Do adenovirus-vector vaccines have beneficial non-specific effects?

25/04/2023 iScience

Authors: Christine S Benn, Frederik Schaltz-Buchholzer, Sebastian Nielsen, Mihai G Netea, Peter Aaby