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featured publications

  • The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use.

    Parasites & vectors

    Authors: Kenneth M Pfarr, Anna K Krome, Issraa Al-Obaidi, Hannah Batchelor, Michel Vaillant, Achim Hoerauf, Nicholas O Opoku, Annette C Kuesel

  • E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.

    Nature immunology

    Authors: Monika Pruenster, Roland Immler, Jonas Roth, Tim Kuchler, Thomas Bromberger, Matteo Napoli, Katrin Nussbaumer, Ina Rohwedder, Lou Martha Wackerbarth, Chiara Piantoni, Konstantin Hennis, Diana Fink, Sebastian Kallabis, Tobias Schroll, Sergi Masgrau-Alsina, Agnes Budke, Wang Liu, Dietmar Vestweber, Christian Wahl-Schott, Johannes Roth, Felix Meissner, Markus Moser, Thomas Vogl, Veit Hornung, Petr Broz, Markus Sperandio

  • Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia.

    Clinical and translational science

    Authors: Robert Greite, Sebastian Schott, Li Wang, Lukas Gohlke, Kirill Kreimann, Katja Derlin, Marcel Gutberlet, Martina Schmidbauer, Andreas Leffler, Igor Tudorache, Jawad Salman, Fabio Ius, Ruslan Natanov, Christine Fegbeutel, Axel Haverich, Ralf Lichtinghagen, Anne M Hüsing, Sibylle von Vietinghoff, Roland Schmitt, Nelli Shushakova, Song Rong, Hermann Haller, Kai M Schmidt-Ott, Magnus Gram, Vijith Vijayan, Irina Scheffner, Wilfried Gwinner, Stephan Immenschuh

  • Identification and comparison of sex-specific serious adverse drug reactions in spontaneous reports and systematically collected reports (ADRED).

    British journal of clinical pharmacology

    Authors: Patrick Christ, Diana Dubrall, Katja Susanne Just, Britta Lewke, Maike Below, Julia Carolin Stingl, Matthias Schmid, Bernhardt Sachs

  • Reconstructing disease dynamics for mechanistic insights and clinical benefit.

    Nature communications

    Authors: Amit Frishberg, Neta Milman, Ayelet Alpert, Hannah Spitzer, Ben Asani, Johannes B Schiefelbein, Evgeny Bakin, Karen Regev-Berman, Siegfried G Priglinger, Joachim L Schultze, Fabian J Theis, Shai S Shen-Orr

  • The global burden of antimicrobial resistance - urinary tract infections.

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    Authors: Sibylle Von Vietinghoff, Olga Shevchuk, Ulrich Dobrindt, Daniel Robert Engel, Selina K Jorch, Christian Kurts, Thomas Miethke, Florian Wagenlehner

  • Gastrointestinal Pathogens in Multi-Infected Individuals: A Cluster Analysis of Interaction.

    Microorganisms

    Authors: Joy Backhaus, Hagen Frickmann, Ralf Matthias Hagen, Gustavo Concha, Ernst Molitor, Achim Hoerauf, Simone Kann

  • Hepatocellular carcinoma extracellular vesicle ECG score as a diagnostic tool close to the ideal.

    Hepatobiliary surgery and nutrition

    Authors: Artur Słomka, Tudor Mocan, Arnulf G Willms, Veronika Lukacs-Kornek, Miroslaw T Kornek

  • Insights into the molecular basis and mechanism of heme-triggered TLR4 signalling: The role of heme-binding motifs in TLR4 and MD2.

    Immunology

    Authors: Marie-T Hopp, Janine Holze, Felicitas Lauber, Laura Holtkamp, Dhruv C Rathod, Maria A Miteva, Elisa B Prestes, Matthias Geyer, Bénédicte Manoury, Nicolas S Merle, Lubka T Roumenina, Marcelo T Bozza, Günther Weindl, Diana Imhof

  • β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4.

    Cell reports

    Authors: Zhiqi Sun, Filippo M Cernilogar, Helena Horvatic, Assa Yeroslaviz, Zeinab Abdullah, Gunnar Schotta, Veit Hornung