Publications

Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner.

08/11/2022 The Journal of experimental medicine

Authors: Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Katharina Isabell Maser, Servi-Remzi Ada, Lukas Sydow, Mona Hajikazemi, Markus Badstübner, Patrick Müller, Yan Ge, Farhad Shakeri, Andreas Buness, Benjamin Rupf, Stefan Lienenklaus, Barbara Utess, Lina Muhandes, Michael Haase, Luise Rupp, Marc Schmitz, Thomas Gramberg, Nicolas Manel, Gunther Hartmann, Thomas Zillinger, Hiroki Kato, Stefan Bauer, Alexander Gerbaulet, Katrin Paeschke, Axel Roers, Rayk Behrendt

Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.

07/11/2022 PLoS biology

Authors: Matthew S J Mangan, Friederike Gorki, Karoline Krause, Alexander Heinz, Anne Pankow, Thomas Ebert, Dieter Jahn, Karsten Hiller, Veit Hornung, Marcus Maurer, Florian I Schmidt, Ralf Gerhard, Eicke Latz

Erratum to 'Linking EORTC QLQ-C-30 and PedsQL/PEDQOL physical functioning scores in patients with osteosarcoma' [Eur J Cancer 170 (2022) 209-235].

05/11/2022 European journal of cancer (Oxford, England : 1990)

Authors: Axel Budde, Katja Baust, Leonie Weinhold, Mark Bernstein, Stefan Bielack, Catharina Dhooge, Lars Hjorth, Katherine A Janeway, Meriel Jenney, Mark D Krailo, Neyssa Marina, Rajaram Nagarajan, Sigbjørn Smeland, Matthew R Sydes, Patricia De Vos, Jeremy Whelan, Andreas Wiener, Gabriele Calaminus, Matthias Schmid

Identification of the onchocerciasis vector in the Kakoi-Koda focus of the Democratic Republic of Congo.

04/11/2022 PLoS neglected tropical diseases

Authors: Rory J Post, Anne Laudisoit, Michel Mandro, Thomson Lakwo, Christine Laemmer, Kenneth Pfarr, Achim Hoerauf, Pablo Tortosa, Yann Gomard, Tony Ukety, Claude Mande, Lorne Farovitch, Uche Amazigo, Didier Bakajika, David W Oguttu, Naomi Awaca, Robert Colebunders

Microtubule retrograde flow retains neuronal polarization in a fluctuating state.

04/11/2022 Science advances

Authors: Max Schelski, Frank Bradke

ATP-binding and hydrolysis of human NLRP3.

03/11/2022 Communications biology

Authors: Rebecca Brinkschulte, David M Fußhöller, Florian Hoss, Juan F Rodríguez-Alcázar, Mario A Lauterbach, Carl-Christian Kolbe, Melanie Rauen, Semra Ince, Christian Herrmann, Eicke Latz, Matthias Geyer

Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19.

03/11/2022 Frontiers in immunology

Authors: Martijn Zoodsma, Aline H de Nooijer, Inge Grondman, Manoj Kumar Gupta, Agnes Bonifacius, Valerie A C M Koeken, Emma Kooistra, Gizem Kilic, Ozlem Bulut, Nina Gödecke, Nico Janssen, Matthijs Kox, Jorge Domínguez-Andrés, Adriaan J van Gammeren, Anton A M Ermens, Andre J A M van der Ven, Peter Pickkers, Rainer Blasczyk, Georg M N Behrens, Frank L van de Veerdonk, Leo A B Joosten, Cheng-Jian Xu, Britta Eiz-Vesper, Mihai G Netea, Yang Li

Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative.

03/11/2022 PLoS genetics

Authors: Guillaume Butler-Laporte, Gundula Povysil, Jack A Kosmicki, Elizabeth T Cirulli, Theodore Drivas, Simone Furini, Chadi Saad, Axel Schmidt, Pawel Olszewski, Urszula Korotko, Mathieu Quinodoz, Elifnaz Çelik, Kousik Kundu, Klaudia Walter, Junghyun Jung, Amy D Stockwell, Laura G Sloofman, Daniel M Jordan, Ryan C Thompson, Diane Del Valle, Nicole Simons, Esther Cheng, Robert Sebra, Eric E Schadt, Seunghee Kim-Schulze, Sacha Gnjatic, Miriam Merad, Joseph D Buxbaum, Noam D Beckmann, Alexander W Charney, Bartlomiej Przychodzen, Timothy Chang, Tess D Pottinger, Ning Shang, Fabian Brand, Francesca Fava, Francesca Mari, Karolina Chwialkowska, Magdalena Niemira, Szymon Pula, J Kenneth Baillie, Alex Stuckey, Antonio Salas, Xabier Bello, Jacobo Pardo-Seco, Alberto Gómez-Carballa, Irene Rivero-Calle, Federico Martinón-Torres, Andrea Ganna, Konrad J Karczewski, Kumar Veerapen, Mathieu Bourgey, Guillaume Bourque, Robert Jm Eveleigh, Vincenzo Forgetta, David Morrison, David Langlais, Mark Lathrop, Vincent Mooser, Tomoko Nakanishi, Robert Frithiof, Michael Hultström, Miklos Lipcsey, Yanara Marincevic-Zuniga, Jessica Nordlund, Kelly M Schiabor Barrett, William Lee, Alexandre Bolze, Simon White, Stephen Riffle, Francisco Tanudjaja, Efren Sandoval, Iva Neveux, Shaun Dabe, Nicolas Casadei, Susanne Motameny, Manal Alaamery, Salam Massadeh, Nora Aljawini, Mansour S Almutairi, Yaseen M Arabi, Saleh A Alqahtani, Fawz S Al Harthi, Amal Almutairi, Fatima Alqubaishi, Sarah Alotaibi, Albandari Binowayn, Ebtehal A Alsolm, Hadeel El Bardisy, Mohammad Fawzy, Fang Cai, Nicole Soranzo, Adam Butterworth, Daniel H Geschwind, Stephanie Arteaga, Alexis Stephens, Manish J Butte, Paul C Boutros, Takafumi N Yamaguchi, Shu Tao, Stefan Eng, Timothy Sanders, Paul J Tung, Michael E Broudy, Yu Pan, Alfredo Gonzalez, Nikhil Chavan, Ruth Johnson, Bogdan Pasaniuc, Brian Yaspan, Sandra Smieszek, Carlo Rivolta, Stephanie Bibert, Pierre-Yves Bochud, Maciej Dabrowski, Pawel Zawadzki, Mateusz Sypniewski, Elżbieta Kaja, Pajaree Chariyavilaskul, Voraphoj Nilaratanakul, Nattiya Hirankarn, Vorasuk Shotelersuk, Monnat Pongpanich, Chureerat Phokaew, Wanna Chetruengchai, Katsushi Tokunaga, Masaya Sugiyama, Yosuke Kawai, Takanori Hasegawa, Tatsuhiko Naito, Ho Namkoong, Ryuya Edahiro, Akinori Kimura, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada, Seiya Imoto, Satoru Miyano, Serghei Mangul, Malak S Abedalthagafi, Hugo Zeberg, Joseph J Grzymski, Nicole L Washington, Stephan Ossowski, Kerstin U Ludwig, Eva C Schulte, Olaf Riess, Marcin Moniuszko, Miroslaw Kwasniewski, Hamdi Mbarek, Said I Ismail, Anurag Verma, David B Goldstein, Krzysztof Kiryluk, Alessandra Renieri, Manuel A R Ferreira, J Brent Richards

Genetic landscape in coagulation factor XIII associated defects - Advances in coagulation and beyond.

02/11/2022 Blood reviews

Authors: Haroon Javed, Sneha Singh, Samhitha Urs Ramaraje Urs, Johannes Oldenburg, Arijit Biswas

Biallelic variants in PIGN cause Fryns syndrome, multiple congenital anomalies-hypotonia-seizures syndrome, and neurologic phenotypes: A genotype-phenotype correlation study.

02/11/2022 Genetics in medicine : official journal of the American College of Medical Genetics

Authors: Lucy Loong, Agostina Tardivo, Alexej Knaus, Mona Hashim, Alistair T Pagnamenta, Kerstin Alt, Helena Böhrer-Rabel, Alfonso Caro-Llopis, Trevor Cole, Felix Distelmaier, Patrick Edery, Carlos R Ferreira, Aleksandra Jezela-Stanek, Bronwyn Kerr, Gerhard Kluger, Peter M Krawitz, Marius Kuhn, Johannes R Lemke, Gaetan Lesca, Sally Ann Lynch, Francisco Martinez, Caroline Maxton, Hanna Mierzewska, Sandra Monfort, Joost Nicolai, Carmen Orellana, Deb K Pal, Rafał Płoski, Oliver W Quarrell, Monica Rosello, Małgorzata Rydzanicz, Ataf Sabir, Robert Śmigiel, Alexander P A Stegmann, Helen Stewart, Constance Stumpel, Elżbieta Szczepanik, Andreas Tzschach, Lynne Wolfe, Jenny C Taylor, Yoshiko Murakami, Taroh Kinoshita, Allan Bayat, Usha Kini