Publications

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.

17/05/2021 Nature genetics

Authors: Niamh Mullins, Andreas J Forstner, Kevin S O'Connell, Brandon Coombes, Jonathan R I Coleman, Zhen Qiao, Thomas D Als, Tim B Bigdeli, Sigrid Børte, Julien Bryois, Alexander W Charney, Ole Kristian Drange, Michael J Gandal, Saskia P Hagenaars, Masashi Ikeda, Nolan Kamitaki, Minsoo Kim, Kristi Krebs, Georgia Panagiotaropoulou, Brian M Schilder, Laura G Sloofman, Stacy Steinberg, Vassily Trubetskoy, Bendik S Winsvold, Hong-Hee Won, Liliya Abramova, Kristina Adorjan, Esben Agerbo, Mariam Al Eissa, Diego Albani, Ney Alliey-Rodriguez, Adebayo Anjorin, Verneri Antilla, Anastasia Antoniou, Swapnil Awasthi, Ji Hyun Baek, Marie Bækvad-Hansen, Nicholas Bass, Michael Bauer, Eva C Beins, Sarah E Bergen, Armin Birner, Carsten Bøcker Pedersen, Erlend Bøen, Marco P Boks, Rosa Bosch, Murielle Brum, Ben M Brumpton, Nathalie Brunkhorst-Kanaan, Monika Budde, Jonas Bybjerg-Grauholm, William Byerley, Murray Cairns, Miquel Casas, Pablo Cervantes, Toni-Kim Clarke, Cristiana Cruceanu, Alfredo Cuellar-Barboza, Julie Cunningham, David Curtis, Piotr M Czerski, Anders M Dale, Nina Dalkner, Friederike S David, Franziska Degenhardt, Srdjan Djurovic, Amanda L Dobbyn, Athanassios Douzenis, Torbjørn Elvsåshagen, Valentina Escott-Price, I Nicol Ferrier, Alessia Fiorentino, Tatiana M Foroud, Liz Forty, Josef Frank, Oleksandr Frei, Nelson B Freimer, Louise Frisén, Katrin Gade, Julie Garnham, Joel Gelernter, Marianne Giørtz Pedersen, Ian R Gizer, Scott D Gordon, Katherine Gordon-Smith, Tiffany A Greenwood, Jakob Grove, José Guzman-Parra, Kyooseob Ha, Magnus Haraldsson, Martin Hautzinger, Urs Heilbronner, Dennis Hellgren, Stefan Herms, Per Hoffmann, Peter A Holmans, Laura Huckins, Stéphane Jamain, Jessica S Johnson, Janos L Kalman, Yoichiro Kamatani, James L Kennedy, Sarah Kittel-Schneider, James A Knowles, Manolis Kogevinas, Maria Koromina, Thorsten M Kranz, Henry R Kranzler, Michiaki Kubo, Ralph Kupka, Steven A Kushner, Catharina Lavebratt, Jacob Lawrence, Markus Leber, Heon-Jeong Lee, Phil H Lee, Shawn E Levy, Catrin Lewis, Calwing Liao, Susanne Lucae, Martin Lundberg, Donald J MacIntyre, Sigurdur H Magnusson, Wolfgang Maier, Adam Maihofer, Dolores Malaspina, Eirini Maratou, Lina Martinsson, Manuel Mattheisen, Steven A McCarroll, Nathaniel W McGregor, Peter McGuffin, James D McKay, Helena Medeiros, Sarah E Medland, Vincent Millischer, Grant W Montgomery, Jennifer L Moran, Derek W Morris, Thomas W Mühleisen, Niamh O'Brien, Claire O'Donovan, Loes M Olde Loohuis, Lilijana Oruc, Sergi Papiol, Antonio F Pardiñas, Amy Perry, Andrea Pfennig, Evgenia Porichi, James B Potash, Digby Quested, Towfique Raj, Mark H Rapaport, J Raymond DePaulo, Eline J Regeer, John P Rice, Fabio Rivas, Margarita Rivera, Julian Roth, Panos Roussos, Douglas M Ruderfer, Cristina Sánchez-Mora, Eva C Schulte, Fanny Senner, Sally Sharp, Paul D Shilling, Engilbert Sigurdsson, Lea Sirignano, Claire Slaney, Olav B Smeland, Daniel J Smith, Janet L Sobell, Christine Søholm Hansen, Maria Soler Artigas, Anne T Spijker, Dan J Stein, John S Strauss, Beata Świątkowska, Chikashi Terao, Thorgeir E Thorgeirsson, Claudio Toma, Paul Tooney, Evangelia-Eirini Tsermpini, Marquis P Vawter, Helmut Vedder, James T R Walters, Stephanie H Witt, Simon Xi, Wei Xu, Jessica Mei Kay Yang, Allan H Young, Hannah Young, Peter P Zandi, Hang Zhou, Lea Zillich, Rolf Adolfsson, Ingrid Agartz, Martin Alda, Lars Alfredsson, Gulja Babadjanova, Lena Backlund, Bernhard T Baune, Frank Bellivier, Susanne Bengesser, Wade H Berrettini, Douglas H R Blackwood, Michael Boehnke, Anders D Børglum, Gerome Breen, Vaughan J Carr, Stanley Catts, Aiden Corvin, Nicholas Craddock, Udo Dannlowski, Dimitris Dikeos, Tõnu Esko, Bruno Etain, Panagiotis Ferentinos, Mark Frye, Janice M Fullerton, Micha Gawlik, Elliot S Gershon, Fernando S Goes, Melissa J Green, Maria Grigoroiu-Serbanescu, Joanna Hauser, Frans Henskens, Jan Hillert, Kyung Sue Hong, David M Hougaard, Christina M Hultman, Kristian Hveem, Nakao Iwata, Assen V Jablensky, Ian Jones, Lisa A Jones, René S Kahn, John R Kelsoe, George Kirov, Mikael Landén, Marion Leboyer, Cathryn M Lewis, Qingqin S Li, Jolanta Lissowska, Christine Lochner, Carmel Loughland, Nicholas G Martin, Carol A Mathews, Fermin Mayoral, Susan L McElroy, Andrew M McIntosh, Francis J McMahon, Ingrid Melle, Patricia Michie, Lili Milani, Philip B Mitchell, Gunnar Morken, Ole Mors, Preben Bo Mortensen, Bryan Mowry, Bertram Müller-Myhsok, Richard M Myers, Benjamin M Neale, Caroline M Nievergelt, Merete Nordentoft, Markus M Nöthen, Michael C O'Donovan, Ketil J Oedegaard, Tomas Olsson, Michael J Owen, Sara A Paciga, Chris Pantelis, Carlos Pato, Michele T Pato, George P Patrinos, Roy H Perlis, Danielle Posthuma, Josep Antoni Ramos-Quiroga, Andreas Reif, Eva Z Reininghaus, Marta Ribasés, Marcella Rietschel, Stephan Ripke, Guy A Rouleau, Takeo Saito, Ulrich Schall, Martin Schalling, Peter R Schofield, Thomas G Schulze, Laura J Scott, Rodney J Scott, Alessandro Serretti, Cynthia Shannon Weickert, Jordan W Smoller, Hreinn Stefansson, Kari Stefansson, Eystein Stordal, Fabian Streit, Patrick F Sullivan, Gustavo Turecki, Arne E Vaaler, Eduard Vieta, John B Vincent, Irwin D Waldman, Thomas W Weickert, Thomas Werge, Naomi R Wray, John-Anker Zwart, Joanna M Biernacka, John I Nurnberger, Sven Cichon, Howard J Edenberg, Eli A Stahl, Andrew McQuillin, Arianna Di Florio, Roel A Ophoff, Ole A Andreassen

Exome-Wide Association Study Identifies FN3KRP and PGP as New Candidate Longevity Genes.

30/04/2021 The journals of gerontology. Series A, Biological sciences and medical sciences

Authors: Guillermo G Torres, Marianne Nygaard, Amke Caliebe, Hélène Blanché, Sophie Chantalat, Pilar Galan, Wolfgang Lieb, Lene Christiansen, Jean-François Deleuze, Kaare Christensen, Konstantin Strauch, Martina Müller-Nurasyid, Annette Peters, Markus M Nöthen, Per Hoffmann, Friederike Flachsbart, Stefan Schreiber, David Ellinghaus, Andre Franke, Janina Dose, Almut Nebel

Interaction of developmental factors and ordinary stressful life events on brain structure in adults.

21/04/2021 NeuroImage. Clinical

Authors: Kai G Ringwald, Tina Meller, Simon Schmitt, Till F M Andlauer, Frederike Stein, Katharina Brosch, Julia-Katharina Pfarr, Olaf Steinsträter, Susanne Meinert, Hannah Lemke, Lena Waltemate, Katharina Thiel, Dominik Grotegerd, Verena Enneking, Melissa Klug, Andreas Jansen, Andreas J Forstner, Fabian Streit, Stephanie H Witt, Marcella Rietschel, Bertram Müller-Myhsok, Markus M Nöthen, Udo Dannlowski, Axel Krug, Igor Nenadić, Tilo Kircher

Germline variation in the insulin-like growth factor pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.

17/04/2021 Carcinogenesis

Authors: Shruti G Dighe, Jianhong Chen, Li Yan, Qianchuan He, Puya Gharahkhani, Lynn Onstad, David M Levine, Claire Palles, Weimin Ye, Marilie D Gammon, Prasad G Iyer, Lesley A Anderson, Geoffrey Liu, Anna H Wu, James Y Dai, Wong-Ho Chow, Harvey A Risch, Jesper Lagergren, Nicholas J Shaheen, Leslie Bernstein, Douglas A Corley, Hans Prenen, John deCaestecker, David MacDonald, Paul Moayyedi, Hugh Barr, Sharon B Love, Laura Chegwidden, Stephen Attwood, Peter Watson, Rebecca Harrison, Katja Ott, Susanne Moebus, Marino Venerito, Hauke Lang, Rupert Mayershofer, Michael Knapp, Lothar Veits, Christian Gerges, Josef Weismüller, Ines Gockel, Yogesh Vashist, Markus M Nöthen, Jakob R Izbicki, Hendrik Manner, Horst Neuhaus, Thomas Rösch, Anne C Böhmer, Arnulf H Hölscher, Mario Anders, Oliver Pech, Brigitte Schumacher, Claudia Schmidt, Thomas Schmidt, Tania Noder, Dietmar Lorenz, Michael Vieth, Andrea May, Timo Hess, Nicole Kreuser, Jessica Becker, Christian Ell, Christine B Ambrosone, Kirsten B Moysich, Stuart MacGregor, Ian Tomlinson, David C Whiteman, Janusz Jankowski, Johannes Schumacher, Thomas L Vaughan, Margaret M Madeleine, Laura J Hardie, Matthew F Buas

Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity.

08/04/2021 Psychological medicine

Authors: Simon Schmitt, Tina Meller, Frederike Stein, Katharina Brosch, Kai Ringwald, Julia-Katharina Pfarr, Clemens Bordin, Nina Peusch, Olaf Steinsträter, Dominik Grotegerd, Katharina Dohm, Susanne Meinert, Katharina Förster, Ronny Redlich, Nils Opel, Tim Hahn, Andreas Jansen, Andreas J Forstner, Fabian Streit, Stephanie H Witt, Marcella Rietschel, Bertram Müller-Myhsok, Markus M Nöthen, Udo Dannlowski, Axel Krug, Tilo Kircher, Igor Nenadić

Genetic factors influencing a neurobiological substrate for psychiatric disorders.

29/03/2021 Translational psychiatry

Authors: Till F M Andlauer, Thomas W Mühleisen, Felix Hoffstaedter, Alexander Teumer, Katharina Wittfeld, Anja Teuber, Céline S Reinbold, Dominik Grotegerd, Robin Bülow, Svenja Caspers, Udo Dannlowski, Stefan Herms, Per Hoffmann, Tilo Kircher, Heike Minnerup, Susanne Moebus, Igor Nenadić, Henning Teismann, Uwe Völker, Amit Etkin, Klaus Berger, Hans J Grabe, Markus M Nöthen, Katrin Amunts, Simon B Eickhoff, Philipp G Sämann, Bertram Müller-Myhsok, Sven Cichon

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.

23/03/2021 Biological psychiatry

Authors: Gabriëlla A M Blokland, Jakob Grove, Chia-Yen Chen, Chris Cotsapas, Stuart Tobet, Robert Handa, David St Clair, Todd Lencz, Bryan J Mowry, Sathish Periyasamy, Murray J Cairns, Paul A Tooney, Jing Qin Wu, Brian Kelly, George Kirov, Patrick F Sullivan, Aiden Corvin, Brien P Riley, Tõnu Esko, Lili Milani, Erik G Jönsson, Aarno Palotie, Hannelore Ehrenreich, Martin Begemann, Agnes Steixner-Kumar, Pak C Sham, Nakao Iwata, Daniel R Weinberger, Pablo V Gejman, Alan R Sanders, Joseph D Buxbaum, Dan Rujescu, Ina Giegling, Bettina Konte, Annette M Hartmann, Elvira Bramon, Robin M Murray, Michele T Pato, Jimmy Lee, Ingrid Melle, Espen Molden, Roel A Ophoff, Andrew McQuillin, Nicholas J Bass, Rolf Adolfsson, Anil K Malhotra, Nicholas G Martin, Janice M Fullerton, Philip B Mitchell, Peter R Schofield, Andreas J Forstner, Franziska Degenhardt, Sabrina Schaupp, Ashley L Comes, Manolis Kogevinas, José Guzman-Parra, Andreas Reif, Fabian Streit, Lea Sirignano, Sven Cichon, Maria Grigoroiu-Serbanescu, Joanna Hauser, Jolanta Lissowska, Fermin Mayoral, Bertram Müller-Myhsok, Beata Świątkowska, Thomas G Schulze, Markus M Nöthen, Marcella Rietschel, John Kelsoe, Marion Leboyer, Stéphane Jamain, Bruno Etain, Frank Bellivier, John B Vincent, Martin Alda, Claire O'Donovan, Pablo Cervantes, Joanna M Biernacka, Mark Frye, Susan L McElroy, Laura J Scott, Eli A Stahl, Mikael Landén, Marian L Hamshere, Olav B Smeland, Srdjan Djurovic, Arne E Vaaler, Ole A Andreassen, Bernhard T Baune, Tracy Air, Martin Preisig, Rudolf Uher, Douglas F Levinson, Myrna M Weissman, James B Potash, Jianxin Shi, James A Knowles, Roy H Perlis, Susanne Lucae, Dorret I Boomsma, Brenda W J H Penninx, Jouke-Jan Hottenga, Eco J C de Geus, Gonneke Willemsen, Yuri Milaneschi, Henning Tiemeier, Hans J Grabe, Alexander Teumer, Sandra Van der Auwera, Uwe Völker, Steven P Hamilton, Patrik K E Magnusson, Alexander Viktorin, Divya Mehta, Niamh Mullins, Mark J Adams, Gerome Breen, Andrew M McIntosh, Cathryn M Lewis, David M Hougaard, Merete Nordentoft, Ole Mors, Preben B Mortensen, Thomas Werge, Thomas D Als, Anders D Børglum, Tracey L Petryshen, Jordan W Smoller, Jill M Goldstein

DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population.

27/02/2021 DNA repair

Authors: Yasmeen Niazi, Hauke Thomsen, Bozena Smolkova, Ludmila Vodickova, Soňa Vodenkova, Michal Kroupa, Veronika Vymetalkova, Alena Kazimirova, Magdalena Barancokova, Katarina Volkovova, Marta Staruchova, Per Hoffmann, Markus M Nöthen, Maria Dusinska, Ludovit Musak, Pavel Vodicka, Asta Försti, Kari Hemminki

"The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment.

15/02/2021 American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

Authors: Urs Heilbronner, Sergi Papiol, Monika Budde, Till F M Andlauer, Jana Strohmaier, Fabian Streit, Josef Frank, Franziska Degenhardt, Stefanie Heilmann-Heimbach, Stephanie H Witt, Andreas J Forstner, Adrian Loerbroks, Manfred Amelang, Til Stürmer, Bertram Müller-Myhsok, Markus M Nöthen, Marcella Rietschel, Thomas G Schulze

Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression.

01/02/2021 JAMA psychiatry

Authors: Nikolaos Koutsouleris, Dominic B Dwyer, Franziska Degenhardt, Carlo Maj, Maria Fernanda Urquijo-Castro, Rachele Sanfelici, David Popovic, Oemer Oeztuerk, Shalaila S Haas, Johanna Weiske, Anne Ruef, Lana Kambeitz-Ilankovic, Linda A Antonucci, Susanne Neufang, Christian Schmidt-Kraepelin, Stephan Ruhrmann, Nora Penzel, Joseph Kambeitz, Theresa K Haidl, Marlene Rosen, Katharine Chisholm, Anita Riecher-Rössler, Laura Egloff, André Schmidt, Christina Andreou, Jarmo Hietala, Timo Schirmer, Georg Romer, Petra Walger, Maurizia Franscini, Nina Traber-Walker, Benno G Schimmelmann, Rahel Flückiger, Chantal Michel, Wulf Rössler, Oleg Borisov, Peter M Krawitz, Karsten Heekeren, Roman Buechler, Christos Pantelis, Peter Falkai, Raimo K R Salokangas, Rebekka Lencer, Alessandro Bertolino, Stefan Borgwardt, Markus Noethen, Paolo Brambilla, Stephen J Wood, Rachel Upthegrove, Frauke Schultze-Lutter, Anastasia Theodoridou, Eva Meisenzahl