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featured publications

  • Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections.

    Journal for immunotherapy of cancer

    Authors: Jelmer H van Puffelen, Boris Novakovic, Liesbeth van Emst, Denise Kooper, Tahlita C M Zuiverloon, Ursula T H Oldenhof, J Alfred Witjes, Tessel E Galesloot, Alina Vrieling, Katja K H Aben, Lambertus A L M Kiemeney, Egbert Oosterwijk, Mihai G Netea, Joost L Boormans, Antoine G van der Heijden, Leo A B Joosten, Sita H Vermeulen

  • T17 cells boosted by nanoparticle-bound fungal motifs.

    Nature biomedical engineering

    Authors: Mihai G Netea, Willem J M Mulder

  • Efficacy and safety of early soluble urokinase plasminogen receptor plasma-guided anakinra treatment of COVID-19 pneumonia: A subgroup analysis of the SAVE-MORE randomised trial.

    EClinicalMedicine

    Authors: Karolina Akinosoglou, Antigone Kotsaki, Ioanna-Maria Gounaridi, Eirini Christaki, Simeon Metallidis, Georgios Adamis, Archontoula Fragkou, Massimo Fantoni, Aggeliki Rapti, Ioannis Kalomenidis, Georgios Chrysos, Gloria Boni, Ilias Kainis, Zoi Alexiou, Francesco Castelli, Francesco Saverio Serino, Petros Bakakos, Emanuele Nicastri, Vassiliki Tzavara, Asimina Safarika, Sofia Ioannou, Lorenzo Dagna, Katerina Dimakou, Glykeria Tzatzagou, Maria Chini, Matteo Bassetti, Vasileios Kotsis, Andrea Angheben, George Tsoukalas, Carlo Selmi, Olga-Maria Spiropoulou, Michael Samarkos, Michael Doumas, Georgia Damoraki, Aikaterini Masgala, Ilias Papanikolaou, Aikaterini Argyraki, Marcantonio Negri, Konstantinos Leventogiannis, Styliani Sympardi, Nikolaos K Gatselis, Vasileios Petrakis, Mihai G Netea, Periklis Panagopoulos, Vissaria Sakka, Haralampos Milionis, George N Dalekos, Evangelos J Giamarellos-Bourboulis

  • The impact of BCG dose and revaccination on trained immunity.

    Clinical immunology (Orlando, Fla.)

    Authors: Priya A Debisarun, Gizem Kilic, L Charlotte J de Bree, Lian J Pennings, Jakko van Ingen, Christine S Benn, Peter Aaby, Helga Dijkstra, Heidi Lemmers, Jorge Domínguez-Andrés, Reinout van Crevel, Mihai G Netea

  • The 2000HIV study: Design, multi-omics methods and participant characteristics.

    Frontiers in immunology

    Authors: Wilhelm A J W Vos, Albert L Groenendijk, Marc J T Blaauw, Louise E van Eekeren, Adriana Navas, Maartje C P Cleophas, Nadira Vadaq, Vasiliki Matzaraki, Jéssica C Dos Santos, Elise M G Meeder, Janeri Fröberg, Gert Weijers, Yue Zhang, Jingyuan Fu, Rob Ter Horst, Christoph Bock, Rainer Knoll, Anna C Aschenbrenner, Joachim Schultze, Linos Vanderkerckhove, Talent Hwandih, Elizabeth R Wonderlich, Sai V Vemula, Mike van der Kolk, Sterre C P de Vet, Willem L Blok, Kees Brinkman, Casper Rokx, Arnt F A Schellekens, Quirijn de Mast, Leo A B Joosten, Marvin A H Berrevoets, Janneke E Stalenhoef, Annelies Verbon, Jan van Lunzen, Mihai G Netea, Andre J A M van der Ven

  • Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study.

    BMC medicine

    Authors: Marwah Doestzada, Daria V Zhernakova, Inge C L van den Munckhof, Daoming Wang, Alexander Kurilshikov, Lianmin Chen, Vincent W Bloks, Martijn van Faassen, Joost H W Rutten, Leo A B Joosten, Mihai G Netea, Cisca Wijmenga, Niels P Riksen, Alexandra Zhernakova, Folkert Kuipers, Jingyuan Fu

  • Interferon gamma-induced protein 10 (IP-10) for the early prognosis of the risk for severe respiratory failure and death in COVID-19 pneumonia.

    Cytokine

    Authors: Charilaos Samaras, Evdoxia Kyriazopoulou, Garyfallia Poulakou, Eran Reiner, Maria Kosmidou, Ioanna Karanika, Vasileios Petrakis, George Adamis, Nikolaos K Gatselis, Archontoula Fragkou, Aggeliki Rapti, Eleonora Taddei, Ioannis Kalomenidis, George Chrysos, Giulia Bertoli, Ilias Kainis, Zoi Alexiou, Francesco Castelli, Francesco Saverio Serino, Petros Bakakos, Emanuele Nicastri, Vassiliki Tzavara, Evangelos Kostis, Lorenzo Dagna, Sofia Koukidou, Glykeria Tzatzagou, Maria Chini, Matteo Bassetti, Christina Trakatelli, George Tsoukalas, Carlo Selmi, Michael Samarkos, Athina Pyrpasopoulou, Aikaterini Masgala, Emmanouil Antonakis, Aikaterini Argyraki, Karolina Akinosoglou, Styliani Sympardi, Periklis Panagopoulos, Haralampos Milionis, Simeon Metallidis, Konstantinos N Syrigos, Alon Angel, George N Dalekos, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Distinct gene programs underpinning disease tolerance and resistance in influenza virus infection.

    Cell systems

    Authors: Ofir Cohn, Gal Yankovitz, Naama Peshes-Yaloz, Yael Steuerman, Amit Frishberg, Rachel Brandes, Michal Mandelboim, Jennifer R Hamilton, Tzachi Hagai, Ido Amit, Mihai G Netea, Nir Hacohen, Fuad A Iraqi, Eran Bacharach, Irit Gat-Viks

  • From trained immunity in allergy to trained immunity-based allergen vaccines.

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

    Authors: Leticia Martín-Cruz, Carmen Sevilla-Ortega, Alba Angelina, Jorge Domínguez-Andrés, Mihai G Netea, José Luis Subiza, Oscar Palomares

  • Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus.

    Microbiology spectrum

    Authors: Daniela Antunes, Samuel M Gonçalves, Vasiliki Matzaraki, Cláudia S Rodrigues, Relber A Gonçales, Joana Rocha, Jorge Sáiz, António Marques, Egídio Torrado, Ricardo Silvestre, Fernando Rodrigues, Frank L van de Veerdonk, Coral Barbas, Mihai G Netea, Vinod Kumar, Cristina Cunha, Agostinho Carvalho