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featured publications

  • Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation.

    Science advances

    Authors: Inga V Hochheiser, Heide Behrmann, Gregor Hagelueken, Juan F Rodríguez-Alcázar, Anja Kopp, Eicke Latz, Elmar Behrmann, Matthias Geyer

  • Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer: A Population-Based Case-Control Study and Meta-Analysis.

    Cancers

    Authors: José Manuel Sánchez-Maldonado, Ricardo Collado, Antonio José Cabrera-Serrano, Rob Ter Horst, Fernando Gálvez-Montosa, Inmaculada Robles-Fernández, Verónica Arenas-Rodríguez, Blanca Cano-Gutiérrez, Olivier Bakker, María Inmaculada Bravo-Fernández, Francisco José García-Verdejo, José Antonio López López, Jesús Olivares-Ruiz, Miguel Ángel López-Nevot, Laura Fernández-Puerta, José Manuel Cózar-Olmo, Yang Li, Mihai G Netea, Manuel Jurado, Jose Antonio Lorente, Pedro Sánchez-Rovira, María Jesús Álvarez-Cubero, Juan Sainz

  • The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.

    Frontiers in immunology

    Authors: Yunus Kuijpers, Xiaojing Chu, Martin Jaeger, Simone J C F M Moorlag, Valerie A C M Koeken, Bowen Zhang, Aline de Nooijer, Inge Grondman, Manoj Kumar Gupta, Nico Janssen, Vera P Mourits, L Charlotte J de Bree, Quirijn de Mast, Frank L van de Veerdonk, Leo A B Joosten, Yang Li, Mihai G Netea, Cheng-Jian Xu

  • Red Blood Cell Distribution Width to Platelet Count Ratio Facilitates Preoperative Prediction of Recurrence in Surgically Treated Chronic Subdural Hematoma.

    Frontiers in neurology

    Authors: Ági Güresir, Christoph Coch, Annkristin Heine, Elvira Mass, Tim Lampmann, Hartmut Vatter, Markus Velten, Marie-Therese Schmitz, Erdem Güresir, Johannes Wach

  • A novel longitudinal clustering approach to psychopathology across diagnostic entities in the hospital-based PsyCourse study.

    Schizophrenia research

    Authors: Eva C Schulte, Ivan Kondofersky, Monika Budde, Sergi Papiol, Fanny Senner, Sabrina K Schaupp, Daniela Reich-Erkelenz, Farahnaz Klöhn-Saghatolislam, Janos L Kalman, Katrin Gade, Maria Hake, Ashley L Comes, Heike Anderson-Schmidt, Kristina Adorjan, Georg Juckel, Max Schmauß, Jörg Zimmermann, Jens Reimer, Jens Wiltfang, Eva Z Reininghaus, Ion-George Anghelescu, Carsten Konrad, Christian Figge, Martin von Hagen, Markus Jäger, Detlef E Dietrich, Carsten Spitzer, Stephanie H Witt, Andreas J Forstner, Marcella Rietschel, Markus M Nöthen, Peter Falkai, Urs Heilbronner, Nikola S Mueller, Thomas G Schulze

  • Gene-independent therapeutic interventions to maintain and restore light sensitivity in degenerating photoreceptors.

    Progress in retinal and eye research

    Authors: Marta Zuzic, Johannes Striebel, Julia S Pawlick, Kritika Sharma, Frank G Holz, Volker Busskamp

  • A Combination of Cytokine-Induced Killer Cells With PD-1 Blockade and ALK Inhibitor Showed Substantial Intrinsic Variability Across Non-Small Cell Lung Cancer Cell Lines.

    Frontiers in oncology

    Authors: Yutao Li, Amit Sharma, Xiaolong Wu, Hans Weiher, Dirk Skowasch, Markus Essler, Ingo G H Schmidt-Wolf

  • Genome Replication Is Associated With Release of Immunogenic DNA Waste.

    Frontiers in immunology

    Authors: Nadja Schubert, Tina Schumann, Elena Daum, Karolin Flade, Yan Ge, Lara Hagedorn, Winfried Edelmann, Luise Müller, Marc Schmitz, Gunnar Kuut, Veit Hornung, Rayk Behrendt, Axel Roers

  • IL-1 Mediates Tissue-Specific Inflammation and Severe Respiratory Failure in COVID-19.

    Journal of innate immunity

    Authors: Georgios Renieris, Eleni Karakike, Theologia Gkavogianni, Dionysia-Eirini Droggiti, Emmanouil Stylianakis, Theano Andriopoulou, Victoria-Marina Spanou, Dionyssios Kafousopoulos, Mihai G Netea, Jesper Eugen-Olsen, John Simard, Evangelos J Giamarellos-Bourboulis

  • [Optogenetics and cell replacement in retinology : Regenerative ophthalmology-What we can do!].

    Die Ophthalmologie

    Authors: Volker Busskamp, Sarah Kunze