Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
Molecular psychiatry
Authors:
Till F M Andlauer, Jose Guzman-Parra, Fabian Streit, Jana Strohmaier, Maria José González, Susana Gil Flores, Francisco J Cabaleiro Fabeiro, Francisco Del Río Noriega, Fermin Perez Perez, Jesus Haro González, Guillermo Orozco Diaz, Yolanda de Diego-Otero, Berta Moreno-Küstner, Georg Auburger, Franziska Degenhardt, Stefanie Heilmann-Heimbach, Stefan Herms, Per Hoffmann, Josef Frank, Jerome C Foo, Jens Treutlein, Stephanie H Witt, Sven Cichon, Manolis Kogevinas, Fabio Rivas, Fermín Mayoral, Bertram Müller-Myhsok, Andreas J Forstner, Markus M Nöthen, Marcella Rietschel
Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression.
The Journal of allergy and clinical immunology
Authors:
Sören Mucha, Hansjörg Baurecht, Natalija Novak, Elke Rodríguez, Saptarshi Bej, Gabriele Mayr, Hila Emmert, Dora Stölzl, Sascha Gerdes, Eun Suk Jung, Frauke Degenhardt, Matthias Hübenthal, Eva Ellinghaus, Jan Christian Kässens, Lars Wienbrandt, Wolfgang Lieb, Martina Müller-Nurasyid, Melanie Hotze, Nick Dand, Sarah Grosche, Ingo Marenholz, Andreas Arnold, Georg Homuth, Carsten O Schmidt, Ulrike Wehkamp, Markus M Nöthen, Per Hoffmann, Lavinia Paternoster, Marie Standl, Klaus Bønnelykke, Tarunveer S Ahluwalia, Hans Bisgaard, Annette Peters, Christian Gieger, Melanie Waldenberger, Holger Schulz, Konstantin Strauch, Thomas Werfel, Young-Ae Lee, Markus Wolfien, Philip Rosenstiel, Olaf Wolkenhauer, Stefan Schreiber, Andre Franke, Stephan Weidinger, David Ellinghaus
Eight novel loci implicate shared genetic etiology in multiple myeloma, AL amyloidosis, and monoclonal gammopathy of unknown significance.
Leukemia
Authors:
Subhayan Chattopadhyay, Hauke Thomsen, Niels Weinhold, Iman Meziane, Stefanie Huhn, Miguel Inacio da Silva Filho, Pavel Vodicka, Ludmila Vodickova, Per Hoffmann, Markus M Nöthen, Karl-Heinz Jöckel, Börge Schmidt, Stefano Landi, Roman Hajek, Göran Hallmans, Ulrika Pettersson-Kymmer, Claes Ohlsson, Paolo Milani, Giampaolo Merlini, Dorota Rowcieno, Philip Hawkins, Ute Hegenbart, Giovanni Palladini, Ashutosh Wechalekar, Stefan O Schönland, Richard Houlston, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.
Nature genetics
Authors:
Rajeev Malhotra, Andreas C Mauer, Christian L Lino Cardenas, Xiuqing Guo, Jie Yao, Xiaoling Zhang, Florian Wunderer, Albert V Smith, Quenna Wong, Sonali Pechlivanis, Shih-Jen Hwang, Judy Wang, Lingyi Lu, Christopher J Nicholson, Georgia Shelton, Mary D Buswell, Hanna J Barnes, Haakon H Sigurslid, Charles Slocum, Caitlin O' Rourke, David K Rhee, Aranya Bagchi, Sagar U Nigwekar, Emmanuel S Buys, Catherine Y Campbell, Tamara Harris, Matthew Budoff, Michael H Criqui, Jerome I Rotter, Andrew D Johnson, Ci Song, Nora Franceschini, Stephanie Debette, Udo Hoffmann, Hagen Kälsch, Markus M Nöthen, Sigurdur Sigurdsson, Barry I Freedman, Donald W Bowden, Karl-Heinz Jöckel, Susanne Moebus, Raimund Erbel, Mary F Feitosa, Vilmundur Gudnason, George Thanassoulis, Warren M Zapol, Mark E Lindsay, Donald B Bloch, Wendy S Post, Christopher J O'Donnell
Genetic architecture of subcortical brain structures in 38,851 individuals.
Nature genetics
Authors:
Claudia L Satizabal, Hieab H H Adams, Derrek P Hibar, Charles C White, Maria J Knol, Jason L Stein, Markus Scholz, Muralidharan Sargurupremraj, Neda Jahanshad, Gennady V Roshchupkin, Albert V Smith, Joshua C Bis, Xueqiu Jian, Michelle Luciano, Edith Hofer, Alexander Teumer, Sven J van der Lee, Jingyun Yang, Lisa R Yanek, Tom V Lee, Shuo Li, Yanhui Hu, Jia Yu Koh, John D Eicher, Sylvane Desrivières, Alejandro Arias-Vasquez, Ganesh Chauhan, Lavinia Athanasiu, Miguel E Rentería, Sungeun Kim, David Hoehn, Nicola J Armstrong, Qiang Chen, Avram J Holmes, Anouk den Braber, Iwona Kloszewska, Micael Andersson, Thomas Espeseth, Oliver Grimm, Lucija Abramovic, Saud Alhusaini, Yuri Milaneschi, Martina Papmeyer, Tomas Axelsson, Stefan Ehrlich, Roberto Roiz-Santiañez, Bernd Kraemer, Asta K Håberg, Hannah J Jones, G Bruce Pike, Dan J Stein, Allison Stevens, Janita Bralten, Meike W Vernooij, Tamara B Harris, Irina Filippi, A Veronica Witte, Tulio Guadalupe, Katharina Wittfeld, Thomas H Mosley, James T Becker, Nhat Trung Doan, Saskia P Hagenaars, Yasaman Saba, Gabriel Cuellar-Partida, Najaf Amin, Saima Hilal, Kwangsik Nho, Nazanin Mirza-Schreiber, Konstantinos Arfanakis, Diane M Becker, David Ames, Aaron L Goldman, Phil H Lee, Dorret I Boomsma, Simon Lovestone, Sudheer Giddaluru, Stephanie Le Hellard, Manuel Mattheisen, Marc M Bohlken, Dalia Kasperaviciute, Lianne Schmaal, Stephen M Lawrie, Ingrid Agartz, Esther Walton, Diana Tordesillas-Gutierrez, Gareth E Davies, Jean Shin, Jonathan C Ipser, Louis N Vinke, Martine Hoogman, Tianye Jia, Ralph Burkhardt, Marieke Klein, Fabrice Crivello, Deborah Janowitz, Owen Carmichael, Unn K Haukvik, Benjamin S Aribisala, Helena Schmidt, Lachlan T Strike, Ching-Yu Cheng, Shannon L Risacher, Benno Pütz, Debra A Fleischman, Amelia A Assareh, Venkata S Mattay, Randy L Buckner, Patrizia Mecocci, Anders M Dale, Sven Cichon, Marco P Boks, Mar Matarin, Brenda W J H Penninx, Vince D Calhoun, M Mallar Chakravarty, Andre F Marquand, Christine Macare, Shahrzad Kharabian Masouleh, Jaap Oosterlaan, Philippe Amouyel, Katrin Hegenscheid, Jerome I Rotter, Andrew J Schork, David C M Liewald, Greig I de Zubicaray, Tien Yin Wong, Li Shen, Philipp G Sämann, Henry Brodaty, Joshua L Roffman, Eco J C de Geus, Magda Tsolaki, Susanne Erk, Kristel R van Eijk, Gianpiero L Cavalleri, Nic J A van der Wee, Andrew M McIntosh, Randy L Gollub, Kazima B Bulayeva, Manon Bernard, Jennifer S Richards, Jayandra J Himali, Markus Loeffler, Nanda Rommelse, Wolfgang Hoffmann, Lars T Westlye, Maria C Valdés Hernández, Narelle K Hansell, Theo G M van Erp, Christiane Wolf, John B J Kwok, Bruno Vellas, Andreas Heinz, Loes M Olde Loohuis, Norman Delanty, Beng-Choon Ho, Christopher R K Ching, Elena Shumskaya, Baljeet Singh, Albert Hofman, Dennis van der Meer, Georg Homuth, Bruce M Psaty, Mark E Bastin, Grant W Montgomery, Tatiana M Foroud, Simone Reppermund, Jouke-Jan Hottenga, Andrew Simmons, Andreas Meyer-Lindenberg, Wiepke Cahn, Christopher D Whelan, Marjolein M J van Donkelaar, Qiong Yang, Norbert Hosten, Robert C Green, Anbupalam Thalamuthu, Sebastian Mohnke, Hilleke E Hulshoff Pol, Honghuang Lin, Clifford R Jack, Peter R Schofield, Thomas W Mühleisen, Pauline Maillard, Steven G Potkin, Wei Wen, Evan Fletcher, Arthur W Toga, Oliver Gruber, Matthew Huentelman, George Davey Smith, Lenore J Launer, Lars Nyberg, Erik G Jönsson, Benedicto Crespo-Facorro, Nastassja Koen, Douglas N Greve, André G Uitterlinden, Daniel R Weinberger, Vidar M Steen, Iryna O Fedko, Nynke A Groenewold, Wiro J Niessen, Roberto Toro, Christophe Tzourio, William T Longstreth, M Kamran Ikram, Jordan W Smoller, Marie-Jose van Tol, Jessika E Sussmann, Tomas Paus, Hervé Lemaître, Matthias L Schroeter, Bernard Mazoyer, Ole A Andreassen, Florian Holsboer, Chantal Depondt, Dick J Veltman, Jessica A Turner, Zdenka Pausova, Gunter Schumann, Daan van Rooij, Srdjan Djurovic, Ian J Deary, Katie L McMahon, Bertram Müller-Myhsok, Rachel M Brouwer, Hilkka Soininen, Massimo Pandolfo, Thomas H Wassink, Joshua W Cheung, Thomas Wolfers, Jean-Luc Martinot, Marcel P Zwiers, Matthias Nauck, Ingrid Melle, Nicholas G Martin, Ryota Kanai, Eric Westman, René S Kahn, Sanjay M Sisodiya, Tonya White, Arvin Saremi, Hans van Bokhoven, Han G Brunner, Henry Völzke, Margaret J Wright, Dennis van 't Ent, Markus M Nöthen, Roel A Ophoff, Jan K Buitelaar, Guillén Fernández, Perminder S Sachdev, Marcella Rietschel, Neeltje E M van Haren, Simon E Fisher, Alexa S Beiser, Clyde Francks, Andrew J Saykin, Karen A Mather, Nina Romanczuk-Seiferth, Catharina A Hartman, Anita L DeStefano, Dirk J Heslenfeld, Michael W Weiner, Henrik Walter, Pieter J Hoekstra, Paul A Nyquist, Barbara Franke, David A Bennett, Hans J Grabe, Andrew D Johnson, Christopher Chen, Cornelia M van Duijn, Oscar L Lopez, Myriam Fornage, Joanna M Wardlaw, Reinhold Schmidt, Charles DeCarli, Philip L De Jager, Arno Villringer, Stéphanie Debette, Vilmundur Gudnason, Sarah E Medland, Joshua M Shulman, Paul M Thompson, Sudha Seshadri, M Arfan Ikram
The genetic relationship between educational attainment and cognitive performance in major psychiatric disorders.
Translational psychiatry
Authors:
Ashley L Comes, Fanny Senner, Monika Budde, Kristina Adorjan, Heike Anderson-Schmidt, Till F M Andlauer, Katrin Gade, Maria Hake, Urs Heilbronner, Janos L Kalman, Daniela Reich-Erkelenz, Farah Klöhn-Saghatolislam, Sabrina K Schaupp, Eva C Schulte, Georg Juckel, Udo Dannlowski, Max Schmauß, Jörg Zimmermann, Jens Reimer, Eva Reininghaus, Ion-George Anghelescu, Volker Arolt, Bernhard T Baune, Carsten Konrad, Andreas Thiel, Andreas J Fallgatter, Vanessa Nieratschker, Christian Figge, Martin von Hagen, Manfred Koller, Thomas Becker, Moritz E Wigand, Markus Jäger, Detlef E Dietrich, Sebastian Stierl, Harald Scherk, Carsten Spitzer, Here Folkerts, Stephanie H Witt, Franziska Degenhardt, Andreas J Forstner, Marcella Rietschel, Markus M Nöthen, Jens Wiltfang, Peter Falkai, Thomas G Schulze, Sergi Papiol
Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes.
Human genomics
Authors:
Molly Went, Ben Kinnersley, Amit Sud, David C Johnson, Niels Weinhold, Asta Försti, Mark van Duin, Giulia Orlando, Jonathan S Mitchell, Rowan Kuiper, Brian A Walker, Walter M Gregory, Per Hoffmann, Graham H Jackson, Markus M Nöthen, Miguel Inacio da Silva Filho, Hauke Thomsen, Annemiek Broyl, Faith E Davies, Unnur Thorsteinsdottir, Markus Hansson, Martin Kaiser, Pieter Sonneveld, Hartmut Goldschmidt, Kari Stefansson, Kari Hemminki, Björn Nilsson, Gareth J Morgan, Richard S Houlston
Effects of a neurodevelopmental genes based polygenic risk score for schizophrenia and single gene variants on brain structure in non-clinical subjects: A preliminary report.
Schizophrenia research
Authors:
Robert Spalthoff, Franziska Degenhardt, Swapnil Awasthi, Stefanie Heilmann-Heimbach, Bianca Besteher, Christian Gaser, Stephan Ripke, Markus M Nöthen, Igor Nenadić