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  • Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.

    Nature communications

    Authors: Ines H Kaltheuner, Kanchan Anand, Jonas Moecking, Robert Düster, Jinhua Wang, Nathanael S Gray, Matthias Geyer

  • Genome-wide interaction study with major depression identifies novel variants associated with cognitive function.

    Molecular psychiatry

    Authors: Anbupalam Thalamuthu, Natalie T Mills, Klaus Berger, Heike Minnerup, Dominik Grotegerd, Udo Dannlowski, Susanne Meinert, Nils Opel, Jonathan Repple, Marius Gruber, Igor Nenadić, Frederike Stein, Katharina Brosch, Tina Meller, Julia-Katharina Pfarr, Andreas J Forstner, Per Hoffmann, Markus M Nöthen, Stephanie Witt, Marcella Rietschel, Tilo Kircher, Mark Adams, Andrew M McIntosh, David J Porteous, Ian J Deary, Caroline Hayward, Archie Campbell, Hans Jörgen Grabe, Alexander Teumer, Georg Homuth, Sandra van der Auwera-Palitschka, K Oliver Schubert, Bernhard T Baune

  • Diagnostics to support elimination of lymphatic filariasis-Development of two target product profiles.

    PLoS neglected tropical diseases

    Authors: Kimberly Y Won, Katherine Gass, Marco Biamonte, Daniel Argaw Dagne, Camilla Ducker, Christopher Hanna, Achim Hoerauf, Patrick J Lammie, Sammy M Njenga, Rahmah Noordin, Kapa D Ramaiah, Reda Ramzy, Ronaldo G Carvalho Scholte, Anthony W Solomon, Ashley A Souza, Jordan Tappero, Emily Toubali, Gary J Weil, Steven A Williams, Jonathan D King

  • The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE-SNARE interactions.

    eLife

    Authors: Jasmin Mertins, Jérôme Finke, Ricarda Sies, Kerstin M Rink, Jan Hasenauer, Thorsten Lang

  • Comparing abrocitinib and dupilumab in the treatment of atopic dermatitis: a plain language summary.

    Immunotherapy

    Authors: Thomas Bieber, Eric L Simpson, Jonathan I Silverberg, Diamant Thaçi, Carle Paul, Andrew E Pink, Yoko Kataoka, Chia-Yu Chu, Marco DiBonaventura, Ricardo Rojo, Jeremias Antinew, Ileana Ionita, Rodney Sinclair, Seth Forman, Jacek Zdybski, Pinaki Biswas, Bimal Malhotra, Fan Zhang, Hernan Valdez

  • Effect of sarcopenia on survival in patients with cirrhosis: A meta-analysis.

    Journal of hepatology

    Authors: Xinxing Tantai, Yi Liu, Yee Hui Yeo, Michael Praktiknjo, Ezequiel Mauro, Yuhei Hamaguchi, Cornelius Engelmann, Peng Zhang, Jae Yoon Jeong, Jeroen Laurens Ad van Vugt, Huijuan Xiao, Huan Deng, Xu Gao, Qing Ye, Jiayuan Zhang, Longbao Yang, Yaqin Cai, Yixin Liu, Na Liu, Zongfang Li, Tao Han, Toshimi Kaido, Joo Hyun Sohn, Christian Strassburg, Thomas Berg, Jonel Trebicka, Yao-Chun Hsu, Jan Nicolaas Maria IJzermans, Jinhai Wang, Grace L Su, Fanpu Ji, Mindie H Nguyen

  • Epigenome-wide association study of alcohol use disorder in five brain regions.

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    Authors: Lea Zillich, Josef Frank, Fabian Streit, Marion M Friske, Jerome C Foo, Lea Sirignano, Stefanie Heilmann-Heimbach, Helene Dukal, Franziska Degenhardt, Per Hoffmann, Anita C Hansson, Markus M Nöthen, Marcella Rietschel, Rainer Spanagel, Stephanie H Witt

  • Novel Biomarkers of Gastric Adenocarcinoma: Current Research and Future Perspectives.

    Cancers

    Authors: Nadja Niclauss, Ines Gütgemann, Jonas Dohmen, Jörg C Kalff, Philipp Lingohr

  • Management of post-operative pancreatic fistulas following Longmire-Traverso pylorus-preserving pancreatoduodenectomy by endoscopic vacuum-assisted closure therapy.

    BMC gastroenterology

    Authors: Dominik J Kaczmarek, Dominik J Heling, Maria A Gonzalez-Carmona, Christian P Strassburg, Vittorio Branchi, Hanno Matthaei, Jörg Kalff, Steffen Manekeller, Tim R Glowka, Tobias J Weismüller

  • Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy.

    Nature communications

    Authors: Matthias Kettwig, Katharina Ternka, Kristin Wendland, Dennis Manfred Krüger, Silvia Zampar, Charlotte Schob, Jonas Franz, Abhishek Aich, Anne Winkler, M Sadman Sakib, Lalit Kaurani, Robert Epple, Hauke B Werner, Samy Hakroush, Julia Kitz, Marco Prinz, Eva Bartok, Gunther Hartmann, Simone Schröder, Peter Rehling, Marco Henneke, Susann Boretius, A Alia, Oliver Wirths, Andre Fischer, Christine Stadelmann, Stefan Nessler, Jutta Gärtner