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featured publications

  • Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus.

    Journal of clinical immunology

    Authors: Annemarie Steiner, Thomas Reygaerts, Alessandra Pontillo, Isabella Ceccherini, Jonas Moecking, Fiona Moghaddas, Sophia Davidson, Francesco Caroli, Alice Grossi, Fabio Fernandes Morato Castro, Jorge Kalil, Florian N Gohr, Florian I Schmidt, Eva Bartok, Thomas Zillinger, Gunther Hartmann, Matthias Geyer, Marco Gattorno, Leonardo Oliveira Mendonça, Seth L Masters

  • Single-cell transcriptomic profiles reveal changes associated with BCG-induced trained immunity and protective effects in circulating monocytes.

    Cell reports

    Authors: Lingjia Kong, Simone J C F M Moorlag, Ariel Lefkovith, Bihua Li, Vasiliki Matzaraki, Liesbeth van Emst, Heather A Kang, Isabel Latorre, Martin Jaeger, Leo A B Joosten, Mihai G Netea, Ramnik J Xavier

  • Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.

    Nature communications

    Authors: Sarah Grosche, Ingo Marenholz, Jorge Esparza-Gordillo, Aleix Arnau-Soler, Erola Pairo-Castineira, Franz Rüschendorf, Tarunveer S Ahluwalia, Catarina Almqvist, Andreas Arnold, Hansjörg Baurecht, Hans Bisgaard, Klaus Bønnelykke, Sara J Brown, Mariona Bustamante, John A Curtin, Adnan Custovic, Shyamali C Dharmage, Ana Esplugues, Mario Falchi, Dietmar Fernandez-Orth, Manuel A R Ferreira, Andre Franke, Sascha Gerdes, Christian Gieger, Hakon Hakonarson, Patrick G Holt, Georg Homuth, Norbert Hubner, Pirro G Hysi, Marjo-Riitta Jarvelin, Robert Karlsson, Gerard H Koppelman, Susanne Lau, Manuel Lutz, Patrik K E Magnusson, Guy B Marks, Martina Müller-Nurasyid, Markus M Nöthen, Lavinia Paternoster, Craig E Pennell, Annette Peters, Konrad Rawlik, Colin F Robertson, Elke Rodriguez, Sylvain Sebert, Angela Simpson, Patrick M A Sleiman, Marie Standl, Dora Stölzl, Konstantin Strauch, Agnieszka Szwajda, Albert Tenesa, Philip J Thompson, Vilhelmina Ullemar, Alessia Visconti, Judith M Vonk, Carol A Wang, Stephan Weidinger, Matthias Wielscher, Catherine L Worth, Chen-Jian Xu, Young-Ae Lee

  • Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation.

    Nature communications

    Authors: Ines H Kaltheuner, Kanchan Anand, Jonas Moecking, Robert Düster, Jinhua Wang, Nathanael S Gray, Matthias Geyer

  • Genome-wide interaction study with major depression identifies novel variants associated with cognitive function.

    Molecular psychiatry

    Authors: Anbupalam Thalamuthu, Natalie T Mills, Klaus Berger, Heike Minnerup, Dominik Grotegerd, Udo Dannlowski, Susanne Meinert, Nils Opel, Jonathan Repple, Marius Gruber, Igor Nenadić, Frederike Stein, Katharina Brosch, Tina Meller, Julia-Katharina Pfarr, Andreas J Forstner, Per Hoffmann, Markus M Nöthen, Stephanie Witt, Marcella Rietschel, Tilo Kircher, Mark Adams, Andrew M McIntosh, David J Porteous, Ian J Deary, Caroline Hayward, Archie Campbell, Hans Jörgen Grabe, Alexander Teumer, Georg Homuth, Sandra van der Auwera-Palitschka, K Oliver Schubert, Bernhard T Baune

  • Diagnostics to support elimination of lymphatic filariasis-Development of two target product profiles.

    PLoS neglected tropical diseases

    Authors: Kimberly Y Won, Katherine Gass, Marco Biamonte, Daniel Argaw Dagne, Camilla Ducker, Christopher Hanna, Achim Hoerauf, Patrick J Lammie, Sammy M Njenga, Rahmah Noordin, Kapa D Ramaiah, Reda Ramzy, Ronaldo G Carvalho Scholte, Anthony W Solomon, Ashley A Souza, Jordan Tappero, Emily Toubali, Gary J Weil, Steven A Williams, Jonathan D King

  • The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE-SNARE interactions.

    eLife

    Authors: Jasmin Mertins, Jérôme Finke, Ricarda Sies, Kerstin M Rink, Jan Hasenauer, Thorsten Lang

  • Comparing abrocitinib and dupilumab in the treatment of atopic dermatitis: a plain language summary.

    Immunotherapy

    Authors: Thomas Bieber, Eric L Simpson, Jonathan I Silverberg, Diamant Thaçi, Carle Paul, Andrew E Pink, Yoko Kataoka, Chia-Yu Chu, Marco DiBonaventura, Ricardo Rojo, Jeremias Antinew, Ileana Ionita, Rodney Sinclair, Seth Forman, Jacek Zdybski, Pinaki Biswas, Bimal Malhotra, Fan Zhang, Hernan Valdez

  • Effect of sarcopenia on survival in patients with cirrhosis: A meta-analysis.

    Journal of hepatology

    Authors: Xinxing Tantai, Yi Liu, Yee Hui Yeo, Michael Praktiknjo, Ezequiel Mauro, Yuhei Hamaguchi, Cornelius Engelmann, Peng Zhang, Jae Yoon Jeong, Jeroen Laurens Ad van Vugt, Huijuan Xiao, Huan Deng, Xu Gao, Qing Ye, Jiayuan Zhang, Longbao Yang, Yaqin Cai, Yixin Liu, Na Liu, Zongfang Li, Tao Han, Toshimi Kaido, Joo Hyun Sohn, Christian Strassburg, Thomas Berg, Jonel Trebicka, Yao-Chun Hsu, Jan Nicolaas Maria IJzermans, Jinhai Wang, Grace L Su, Fanpu Ji, Mindie H Nguyen

  • Epigenome-wide association study of alcohol use disorder in five brain regions.

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

    Authors: Lea Zillich, Josef Frank, Fabian Streit, Marion M Friske, Jerome C Foo, Lea Sirignano, Stefanie Heilmann-Heimbach, Helene Dukal, Franziska Degenhardt, Per Hoffmann, Anita C Hansson, Markus M Nöthen, Marcella Rietschel, Rainer Spanagel, Stephanie H Witt