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  • Efficient gradient-based parameter estimation for dynamic models using qualitative data.

    Bioinformatics (Oxford, England)

    Authors: Leonard Schmiester, Daniel Weindl, Jan Hasenauer

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  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).

    European journal of immunology

    Authors: Andrea Cossarizza, Hyun-Dong Chang, Andreas Radbruch, Sergio Abrignani, Richard Addo, Mübeccel Akdis, Immanuel Andrä, Francesco Andreata, Francesco Annunziato, Eduardo Arranz, Petra Bacher, Sudipto Bari, Vincenzo Barnaba, Joana Barros-Martins, Dirk Baumjohann, Cristian G Beccaria, David Bernardo, Dominic A Boardman, Jessica Borger, Chotima Böttcher, Leonie Brockmann, Marie Burns, Dirk H Busch, Garth Cameron, Ilenia Cammarata, Antonino Cassotta, Yinshui Chang, Fernando Gabriel Chirdo, Eleni Christakou, Luka Čičin-Šain, Laura Cook, Alexandra J Corbett, Rebecca Cornelis, Lorenzo Cosmi, Martin S Davey, Sara De Biasi, Gabriele De Simone, Genny Del Zotto, Michael Delacher, Francesca Di Rosa, James Di Santo, Andreas Diefenbach, Jun Dong, Thomas Dörner, Regine J Dress, Charles-Antoine Dutertre, Sidonia B G Eckle, Pascale Eede, Maximilien Evrard, Christine S Falk, Markus Feuerer, Simon Fillatreau, Aida Fiz-Lopez, Marie Follo, Gemma A Foulds, Julia Fröbel, Nicola Gagliani, Giovanni Galletti, Anastasia Gangaev, Natalio Garbi, José Antonio Garrote, Jens Geginat, Nicholas A Gherardin, Lara Gibellini, Florent Ginhoux, Dale I Godfrey, Paola Gruarin, Claudia Haftmann, Leo Hansmann, Christopher M Harpur, Adrian C Hayday, Guido Heine, Daniela Carolina Hernández, Martin Herrmann, Oliver Hoelsken, Qing Huang, Samuel Huber, Johanna E Huber, Jochen Huehn, Michael Hundemer, William Y K Hwang, Matteo Iannacone, Sabine M Ivison, Hans-Martin Jäck, Peter K Jani, Baerbel Keller, Nina Kessler, Steven Ketelaars, Laura Knop, Jasmin Knopf, Hui-Fern Koay, Katja Kobow, Katharina Kriegsmann, H Kristyanto, Andreas Krueger, Jenny F Kuehne, Heike Kunze-Schumacher, Pia Kvistborg, Immanuel Kwok, Daniela Latorre, Daniel Lenz, Megan K Levings, Andreia C Lino, Francesco Liotta, Heather M Long, Enrico Lugli, Katherine N MacDonald, Laura Maggi, Mala K Maini, Florian Mair, Calin Manta, Rudolf Armin Manz, Mir-Farzin Mashreghi, Alessio Mazzoni, James McCluskey, Henrik E Mei, Fritz Melchers, Susanne Melzer, Dirk Mielenz, Leticia Monin, Lorenzo Moretta, Gabriele Multhoff, Luis Enrique Muñoz, Miguel Muñoz-Ruiz, Franziska Muscate, Ambra Natalini, Katrin Neumann, Lai Guan Ng, Antonia Niedobitek, Jana Niemz, Larissa Nogueira Almeida, Samuele Notarbartolo, Lennard Ostendorf, Laura J Pallett, Amit A Patel, Gulce Itir Percin, Giovanna Peruzzi, Marcello Pinti, A Graham Pockley, Katharina Pracht, Immo Prinz, Irma Pujol-Autonell, Nadia Pulvirenti, Linda Quatrini, Kylie M Quinn, Helena Radbruch, Hefin Rhys, Maria B Rodrigo, Chiara Romagnani, Carina Saggau, Shimon Sakaguchi, Federica Sallusto, Lieke Sanderink, Inga Sandrock, Christine Schauer, Alexander Scheffold, Hans U Scherer, Matthias Schiemann, Frank A Schildberg, Kilian Schober, Janina Schoen, Wolfgang Schuh, Thomas Schüler, Axel R Schulz, Sebastian Schulz, Julia Schulze, Sonia Simonetti, Jeeshan Singh, Katarzyna M Sitnik, Regina Stark, Sarah Starossom, Christina Stehle, Franziska Szelinski, Leonard Tan, Attila Tarnok, Julia Tornack, Timothy I M Tree, Jasper J P van Beek, Willem van de Veen, Klaas van Gisbergen, Chiara Vasco, Nikita A Verheyden, Anouk von Borstel, Kirsten A Ward-Hartstonge, Klaus Warnatz, Claudia Waskow, Annika Wiedemann, Anneke Wilharm, James Wing, Oliver Wirz, Jens Wittner, Jennie H M Yang, Juhao Yang

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  • Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.

    Nature cell biology

    Authors: Julia P Gerber, Jenny Russ, Vijay Chandrasekar, Nina Offermann, Hang-Mao Lee, Sarah Spear, Nicola Guzzi, Simona Maida, Sundararaghavan Pattabiraman, Ruoyu Zhang, Amir H Kayvanjoo, Preeta Datta, Jagath Kasturiarachchi, Teresa Sposito, Natalia Izotova, Kristian Händler, Peter D Adams, Teresa Marafioti, Tariq Enver, Jörg Wenzel, Marc Beyer, Elvira Mass, Cristian Bellodi, Joachim L Schultze, Melania Capasso, Rachael Nimmo, Paolo Salomoni

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  • Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Marcia N Gordon, Michael T Heneka, Lydia M Le Page, Christian Limberger, David Morgan, Andrea J Tenner, Niccolò Terrando, Auriel A Willette, Sara A Willette

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  • C-reactive protein flare-response predicts long-term efficacy to first-line anti-PD-1-based combination therapy in metastatic renal cell carcinoma.

    Clinical & translational immunology

    Authors: Niklas Klümper, Philipp Schmucker, Oliver Hahn, Benedikt Höh, Angelika Mattigk, Severine Banek, Jörg Ellinger, Julia Heinzelbecker, Danijel Sikic, Markus Eckstein, Arne Strauß, Friedemann Zengerling, Michael Hölzel, Philip Zeuschner, Charis Kalogirou

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  • Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.

    Nature genetics

    Authors: Wouter van Rheenen, Rick A A van der Spek, Mark K Bakker, Joke J F A van Vugt, Paul J Hop, Ramona A J Zwamborn, Niek de Klein, Harm-Jan Westra, Olivier B Bakker, Patrick Deelen, Gemma Shireby, Eilis Hannon, Matthieu Moisse, Denis Baird, Restuadi Restuadi, Egor Dolzhenko, Annelot M Dekker, Klara Gawor, Henk-Jan Westeneng, Gijs H P Tazelaar, Kristel R van Eijk, Maarten Kooyman, Ross P Byrne, Mark Doherty, Mark Heverin, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Nicola Ticozzi, Johnathan Cooper-Knock, Bradley N Smith, Marta Gromicho, Siddharthan Chandran, Suvankar Pal, Karen E Morrison, Pamela J Shaw, John Hardy, Richard W Orrell, Michael Sendtner, Thomas Meyer, Nazli Başak, Anneke J van der Kooi, Antonia Ratti, Isabella Fogh, Cinzia Gellera, Giuseppe Lauria, Stefania Corti, Cristina Cereda, Daisy Sproviero, Sandra D'Alfonso, Gianni Sorarù, Gabriele Siciliano, Massimiliano Filosto, Alessandro Padovani, Adriano Chiò, Andrea Calvo, Cristina Moglia, Maura Brunetti, Antonio Canosa, Maurizio Grassano, Ettore Beghi, Elisabetta Pupillo, Giancarlo Logroscino, Beatrice Nefussy, Alma Osmanovic, Angelica Nordin, Yossef Lerner, Michal Zabari, Marc Gotkine, Robert H Baloh, Shaughn Bell, Patrick Vourc'h, Philippe Corcia, Philippe Couratier, Stéphanie Millecamps, Vincent Meininger, François Salachas, Jesus S Mora Pardina, Abdelilah Assialioui, Ricardo Rojas-García, Patrick A Dion, Jay P Ross, Albert C Ludolph, Jochen H Weishaupt, David Brenner, Axel Freischmidt, Gilbert Bensimon, Alexis Brice, Alexandra Durr, Christine A M Payan, Safa Saker-Delye, Nicholas W Wood, Simon Topp, Rosa Rademakers, Lukas Tittmann, Wolfgang Lieb, Andre Franke, Stephan Ripke, Alice Braun, Julia Kraft, David C Whiteman, Catherine M Olsen, Andre G Uitterlinden, Albert Hofman, Marcella Rietschel, Sven Cichon, Markus M Nöthen, Philippe Amouyel, Bryan J Traynor, Andrew B Singleton, Miguel Mitne Neto, Ruben J Cauchi, Roel A Ophoff, Martina Wiedau-Pazos, Catherine Lomen-Hoerth, Vivianna M van Deerlin, Julian Grosskreutz, Annekathrin Roediger, Nayana Gaur, Alexander Jörk, Tabea Barthel, Erik Theele, Benjamin Ilse, Beatrice Stubendorff, Otto W Witte, Robert Steinbach, Christian A Hübner, Caroline Graff, Lev Brylev, Vera Fominykh, Vera Demeshonok, Anastasia Ataulina, Boris Rogelj, Blaž Koritnik, Janez Zidar, Metka Ravnik-Glavač, Damjan Glavač, Zorica Stević, Vivian Drory, Monica Povedano, Ian P Blair, Matthew C Kiernan, Beben Benyamin, Robert D Henderson, Sarah Furlong, Susan Mathers, Pamela A McCombe, Merrilee Needham, Shyuan T Ngo, Garth A Nicholson, Roger Pamphlett, Dominic B Rowe, Frederik J Steyn, Kelly L Williams, Karen A Mather, Perminder S Sachdev, Anjali K Henders, Leanne Wallace, Mamede de Carvalho, Susana Pinto, Susanne Petri, Markus Weber, Guy A Rouleau, Vincenzo Silani, Charles J Curtis, Gerome Breen, Jonathan D Glass, Robert H Brown, John E Landers, Christopher E Shaw, Peter M Andersen, Ewout J N Groen, Michael A van Es, R Jeroen Pasterkamp, Dongsheng Fan, Fleur C Garton, Allan F McRae, George Davey Smith, Tom R Gaunt, Michael A Eberle, Jonathan Mill, Russell L McLaughlin, Orla Hardiman, Kevin P Kenna, Naomi R Wray, Ellen Tsai, Heiko Runz, Lude Franke, Ammar Al-Chalabi, Philip Van Damme, Leonard H van den Berg, Jan H Veldink

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  • Simultaneous recording of multiple cellular signaling events by frequency- and spectrally-tuned multiplexing of fluorescent probes.

    eLife

    Authors: Michelina Kierzek, Parker E Deal, Evan W Miller, Shatanik Mukherjee, Dagmar Wachten, Arnd Baumann, U Benjamin Kaupp, Timo Strünker, Christoph Brenker

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  • The Different Immune Profiles of Normal Colonic Mucosa in Cancer-Free Lynch Syndrome Carriers and Lynch Syndrome Colorectal Cancer Patients.

    Gastroenterology

    Authors: Lena Bohaumilitzky, Klaus Kluck, Robert Hüneburg, Richard Gallon, Jacob Nattermann, Martina Kirchner, Glen Kristiansen, Oliver Hommerding, Pauline L Pfuderer, Lelia Wagner, Fabian Echterdiek, Svenja Kösegi, Nico Müller, Konstantin Fischer, Nina Nelius, Ben Hartog, Gillian Borthwick, Elena Busch, Georg Martin Haag, Hendrik Bläker, Gabriela Möslein, Magnus von Knebel Doeberitz, Toni T Seppälä, Maarit Ahtiainen, Jukka-Pekka Mecklin, D Timothy Bishop, John Burn, Albrecht Stenzinger, Jan Budczies, Matthias Kloor, Aysel Ahadova

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  • GGCX variants leading to biallelic deficiency to γ-carboxylate GRP cause skin laxity in VKCFD1 patients.

    Human mutation

    Authors: Suvoshree Ghosh, Katrin Kraus, Arijit Biswas, Jens Müller, Francesco Forin, Heike Singer, Klara Höning, Veit Hornung, Matthias Watzka, Johannes Oldenburg, Katrin J Czogalla-Nitsche

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  • Variceal bleeding has increased mortality compared to nonvariceal bleeding only in males.

    European journal of gastroenterology & hepatology

    Authors: Hans-Peter Erasmus, Rukiye Bektas, Katharina Orland, Svetlozara Trifonova, Wen-Yi Gu, Frank Erhard Uschner, Maximilian J Brol, Johannes Chang, Michael Praktiknjo, Christian P Strassburg, Jonel Trebicka, Christian Jansen

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