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featured publications

  • Subcutaneous birch pollen allergen immunotherapy with a depigmented polymerized extract shows only sustained and long-term efficacy in a subgroup of monosensitized adults and adolescents with allergic rhinitis.

    Clinical and translational allergy

    Authors: Natalija Novak, Margitta Worm, Petra Staubach, Marek Jutel, Angelika Sager, Oliver Pfaar

  • Long-term morphological and functional dynamics of human stem cell-derived neuronal networks on high-density micro-electrode arrays.

    Frontiers in neuroscience

    Authors: Rouhollah Habibey, Johannes Striebel, Felix Schmieder, Jürgen Czarske, Volker Busskamp

  • Genetics in parkinson's disease: From better disease understanding to machine learning based precision medicine.

    Frontiers in molecular medicine

    Authors: Mohamed Aborageh, Peter Krawitz, Holger Fröhlich

  • Next-generation phenotyping contributing to the identification of a 4.7 kb deletion in KANSL1 causing Koolen-de Vries syndrome.

    Human mutation

    Authors: Fabian Brand, Aswinkumar Vijayananth, Tzung-Chien Hsieh, Axel Schmidt, Sophia Peters, Elisabeth Mangold, Kirsten Cremer, Tim Bender, Sugirthan Sivalingam, Hela Hundertmark, Alexej Knaus, Hartmut Engels, Peter M Krawitz, Claudia Perne

  • Genetic lessons learned from pathogenic variants in KRT1.

    Journal of the European Academy of Dermatology and Venereology : JEADV

    Authors: Regina C Betz

  • Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas.

    Acta neuropathologica

    Authors: Tobias Goschzik, Martin Mynarek, Evelyn Doerner, Alina Schenk, Isabel Spier, Monika Warmuth-Metz, Brigitte Bison, Denise Obrecht, Nina Struve, Rolf-Dieter Kortmann, Matthias Schmid, Stefan Aretz, Stefan Rutkowski, Torsten Pietsch

  • Myeloid But Not Endothelial Expression of the CB2 Receptor Promotes Atherogenesis in the Context of Elevated Levels of the Endocannabinoid 2-Arachidonoylglycerol.

    Journal of cardiovascular translational research

    Authors: Elina Avraamidou, Moritz Nöthel, Melina Danisch, Laura Bindila, Susanne V Schmidt, Beat Lutz, Georg Nickenig, Julian Jehle

  • Clinical experience of switching patients with severe hemophilia to rVIII-SingleChain or rIX-FP.

    Current medical research and opinion

    Authors: Johannes Oldenburg, Steven W Pipe, Maria Elisa Mancuso, Robert Klamroth, Abel Hassoun, Martin Olivieri, Georg Goldmann, Gili Kenet, Wolfgang Miesbach, Jolana Schmiedl, Inga Hegemann

  • Microbiome-Related Indole and Serotonin Metabolites are Linked to Inflammation and Psychiatric Symptoms in People Living with HIV.

    International journal of tryptophan research : IJTR

    Authors: Nadira Vadaq, Yue Zhang, Elise Meeder, Lisa Van de Wijer, Muhammad Hussein Gasem, Leo Ab Joosten, Mihai G Netea, Quirijn de Mast, Vasiliki Matzaraki, Arnt Schellekens, Jingyuan Fu, André Jam van der Ven

  • Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.

    Genome medicine

    Authors: Neha Mishra, Konrad Aden, Johanna I Blase, Nathan Baran, Dora Bordoni, Florian Tran, Claudio Conrad, Diana Avalos, Charlot Jaeckel, Michael Scherer, Signe B Sørensen, Silja H Overgaard, Berenice Schulte, Susanna Nikolaus, Guillaume Rey, Gilles Gasparoni, Paul A Lyons, Joachim L Schultze, Jörn Walter, Vibeke Andersen, Emmanouil T Dermitzakis, Stefan Schreiber, Philip Rosenstiel