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  • Top publication

    Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

    Immunity

    Authors: Benjamin Krämer, Rainer Knoll, Lorenzo Bonaguro, Michael ToVinh, Jan Raabe, Rosario Astaburuaga-García, Jonas Schulte-Schrepping, Kim Melanie Kaiser, Gereon J Rieke, Jenny Bischoff, Malte B Monin, Christoph Hoffmeister, Stefan Schlabe, Elena De Domenico, Nico Reusch, Kristian Händler, Gary Reynolds, Nils Blüthgen, Gudrun Hack, Claudia Finnemann, Hans D Nischalke, Christian P Strassburg, Emily Stephenson, Yapeng Su, Louis Gardner, Dan Yuan, Daniel Chen, Jason Goldman, Philipp Rosenstiel, Susanne V Schmidt, Eicke Latz, Kevin Hrusovsky, Andrew J Ball, Joe M Johnson, Paul-Albert Koenig, Florian I Schmidt, Muzlifah Haniffa, James R Heath, Beate M Kümmerer, Verena Keitel, Björn Jensen, Paula Stubbemann, Florian Kurth, Leif E Sander, Birgit Sawitzki, Anna C Aschenbrenner, Joachim L Schultze, Jacob Nattermann

  • Primary Stability in Hip Revision Arthroplasty: Comparison of the Stability of Cementless Fixed Augments on a Modular Acetabular Cage System with and without Cranial Straps.

    Journal of clinical medicine

    Authors: Max Jaenisch, Hendrik Kohlhof, Dieter Christian Wirtz, Frank Alexander Schildberg, Nicholas A Beckmann, Jan Philippe Kretzer, Mareike Schonhoff, Sebastian Jäger

  • Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial.

    Nature medicine

    Authors: Evdoxia Kyriazopoulou, Garyfallia Poulakou, Haralampos Milionis, Simeon Metallidis, Georgios Adamis, Konstantinos Tsiakos, Archontoula Fragkou, Aggeliki Rapti, Christina Damoulari, Massimo Fantoni, Ioannis Kalomenidis, Georgios Chrysos, Andrea Angheben, Ilias Kainis, Zoi Alexiou, Francesco Castelli, Francesco Saverio Serino, Maria Tsilika, Petros Bakakos, Emanuele Nicastri, Vassiliki Tzavara, Evangelos Kostis, Lorenzo Dagna, Panagiotis Koufargyris, Katerina Dimakou, Spyridon Savvanis, Glykeria Tzatzagou, Maria Chini, Giulio Cavalli, Matteo Bassetti, Konstantina Katrini, Vasileios Kotsis, George Tsoukalas, Carlo Selmi, Ioannis Bliziotis, Michael Samarkos, Michael Doumas, Sofia Ktena, Aikaterini Masgala, Ilias Papanikolaou, Maria Kosmidou, Dimitra-Melia Myrodia, Aikaterini Argyraki, Chiara Simona Cardellino, Katerina Koliakou, Eleni-Ioanna Katsigianni, Vassiliki Rapti, Efthymia Giannitsioti, Antonella Cingolani, Styliani Micha, Karolina Akinosoglou, Orestis Liatsis-Douvitsas, Styliani Symbardi, Nikolaos Gatselis, Maria Mouktaroudi, Giuseppe Ippolito, Eleni Florou, Antigone Kotsaki, Mihai G Netea, Jesper Eugen-Olsen, Miltiades Kyprianou, Periklis Panagopoulos, George N Dalekos, Evangelos J Giamarellos-Bourboulis

  • CADA: phenotype-driven gene prioritization based on a case-enriched knowledge graph.

    NAR genomics and bioinformatics

    Authors: Chengyao Peng, Simon Dieck, Alexander Schmid, Ashar Ahmad, Alexej Knaus, Maren Wenzel, Laura Mehnert, Birgit Zirn, Tobias Haack, Stephan Ossowski, Matias Wagner, Theresa Brunet, Nadja Ehmke, Magdalena Danyel, Stanislav Rosnev, Tom Kamphans, Guy Nadav, Nicole Fleischer, Holger Fröhlich, Peter Krawitz

  • Design of the HEM-POWR study: a prospective, observational study of real-world treatment with damoctocog alfa pegol in patients with haemophilia A.

    BMJ open

    Authors: Martin Sanabria, María Teresa Álvarez Román, Giancarlo Castaman, Maissaa Janbain, Tadashi Matsushita, Karina Meijer, Johannes Oldenburg, Sabine Friedl, M T Reding

  • DeepCNV: a deep learning approach for authenticating copy number variations.

    Briefings in bioinformatics

    Authors: Joseph T Glessner, Xiurui Hou, Cheng Zhong, Jie Zhang, Munir Khan, Fabian Brand, Peter Krawitz, Patrick M A Sleiman, Hakon Hakonarson, Zhi Wei

  • A Combined TLR7/TLR9/GATA3 Score Can Predict Prognosis in Biliary Tract Cancer.

    Diagnostics (Basel, Switzerland)

    Authors: Vittorio Branchi, Laura Esser, Corinna Boden, Azin Jafari, Jonas Henn, Philipp Lingohr, Maria A Gonzalez-Carmona, Marc Schmitz, Tobias J Weismüller, Christian P Strassburg, Steffen Manekeller, Glen Kristiansen, Jörg C Kalff, Hanno Matthaei, Marieta I Toma

  • Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization.

    Molecular human reproduction

    Authors: Melanie Balbach, Lubna Ghanem, Thomas Rossetti, Navpreet Kaur, Carla Ritagliati, Jacob Ferreira, Dario Krapf, Lis C Puga Molina, Celia Maria Santi, Jan Niklas Hansen, Dagmar Wachten, Makoto Fushimi, Peter T Meinke, Jochen Buck, Lonny R Levin

  • US-guided high-intensity focused ultrasound (HIFU) of abdominal tumors: outcome, early ablation-related laboratory changes and inflammatory reaction. A single-center experience from Germany.

    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

    Authors: Tolga Tonguc, Holger Strunk, Maria A Gonzalez-Carmona, Florian Recker, Dieter Lütjohann, Marcus Thudium, Rupert Conrad, Marc U Becher, Oleksandr Savchenko, Darya Davidova, Guido Luechters, Alexander Mustea, Christian P Strassburg, Ulrike Attenberger, Claus C Pieper, Jürgen Jenne, Milka Marinova

  • Neuronal Cell-type Engineering by Transcriptional Activation.

    Frontiers in genome editing

    Authors: Songlei Liu, Johannes Striebel, Giovanni Pasquini, Alex H M Ng, Parastoo Khoshakhlagh, George M Church, Volker Busskamp