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featured publications

  • Machine learning to guide clinical decision-making in abdominal surgery-a systematic literature review.

    Langenbeck's archives of surgery

    Authors: Jonas Henn, Andreas Buness, Matthias Schmid, Jörg C Kalff, Hanno Matthaei

  • Combining FORGE Score and Histopathological Diagnostic Criteria of Atypical Meningioma Enables Risk Stratification of Tumor Progression.

    Diagnostics (Basel, Switzerland)

    Authors: Johannes Wach, Tim Lampmann, Ági Güresir, Hartmut Vatter, Albert J Becker, Michael Hölzel, Marieta Toma, Erdem Güresir

  • Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing.

    Cell metabolism

    Authors: Sebastian Willenborg, David E Sanin, Alexander Jais, Xiaolei Ding, Thomas Ulas, Julian Nüchel, Milica Popović, Thomas MacVicar, Thomas Langer, Joachim L Schultze, Alexander Gerbaulet, Axel Roers, Edward J Pearce, Jens C Brüning, Aleksandra Trifunovic, Sabine A Eming

  • Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.

    Blood

    Authors: Raffaella Molteni, Riccardo Biavasco, Davide Stefanoni, Travis Nemkov, Jorge Domínguez-Andrés, Rob J Arts, Ivan Merelli, Davide Mazza, Samuel Zambrano, Maddalena Panigada, Eleonora Cantoni, Isak W Tengesdal, Philippe Maksud, Francesco Piras, Daniela Cesana, Laura Cassina, Gianfranco Distefano, Alessia Loffreda, Daniela Gnani, Giacomo De Luca, Alessandro Tomelleri, Corrado Campochiaro, Leo A B Joosten, Charles A Dinarello, Anna Kajaste-Rudnitski, Julien Haroche, Simone Cardaci, Simone Cenci, Lorenzo Dagna, Claudio Doglioni, Marina Ferrarini, Elisabetta Ferrero, Alessandra Boletta, Angelo D'Alessandro, Eugenio Montini, Mihai G Netea, Giulio Cavalli

  • Vitamin K Epoxide Reductase Complex Subunit 1-Like 1 (VKORC1L1) Inhibition Induces a Proliferative and Pro-inflammatory Vascular Smooth Muscle Cell Phenotype.

    Frontiers in cardiovascular medicine

    Authors: Adem Aksoy, Muntadher Al Zaidi, Elena Repges, Marc Ulrich Becher, Cornelius Müller, Johannes Oldenburg, Sebastian Zimmer, Georg Nickenig, Vedat Tiyerili

  • Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts.

    Frontiers in immunology

    Authors: Jose Manuel Sánchez-Maldonado, Rafael Cáliz, Miguel Ángel López-Nevot, Antonio José Cabrera-Serrano, Ana Moñiz-Díez, Helena Canhão, Rob Ter Horst, Luca Quartuccio, Signe B Sorensen, Bente Glintborg, Merete L Hetland, Ileana Filipescu, Eva Pérez-Pampin, Pablo Conesa-Zamora, Jerzy Swierkot, Alfons A den Broeder, Salvatore De Vita, Eva Rabing Brix Petersen, Yang Li, Miguel A Ferrer, Alejandro Escudero, Mihai G Netea, Marieke J H Coenen, Vibeke Andersen, João E Fonseca, Manuel Jurado, Katarzyna Bogunia-Kubik, Eduardo Collantes, Juan Sainz

  • An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.

    Neuron

    Authors: Brett J Hilton, Andreas Husch, Barbara Schaffran, Tien-Chen Lin, Emily R Burnside, Sebastian Dupraz, Max Schelski, Jisoo Kim, Johannes Alexander Müller, Susanne Schoch, Cordelia Imig, Nils Brose, Frank Bradke

  • Induction of trained immunity by influenza vaccination - impact on COVID-19.

    PLoS pathogens

    Authors: Priya A Debisarun, Katharina L Gössling, Ozlem Bulut, Gizem Kilic, Martijn Zoodsma, Zhaoli Liu, Marina Oldenburg, Nadine Rüchel, Bowen Zhang, Cheng-Jian Xu, Patrick Struycken, Valerie A C M Koeken, Jorge Domínguez-Andrés, Simone J C F M Moorlag, Esther Taks, Philipp N Ostermann, Lisa Müller, Heiner Schaal, Ortwin Adams, Arndt Borkhardt, Jaap Ten Oever, Reinout van Crevel, Yang Li, Mihai G Netea

  • AMICI: high-performance sensitivity analysis for large ordinary differential equation models.

    Bioinformatics (Oxford, England)

    Authors: Fabian Fröhlich, Daniel Weindl, Yannik Schälte, Dilan Pathirana, Łukasz Paszkowski, Glenn Terje Lines, Paul Stapor, Jan Hasenauer

  • CD4+ T cell immunity to Salmonella is transient in the circulation.

    PLoS pathogens

    Authors: Newton G Peres, Nancy Wang, Paul Whitney, Sven Engel, Meghanashree M Shreenivas, Ian Comerford, Dianna M Hocking, Anna B Erazo, Irmgard Förster, Andreas Kupz, Thomas Gebhardt, Shaun R McColl, Stephen J McSorley, Sammy Bedoui, Richard A Strugnell