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featured publications

  • Inhibition of Rac1 GTPase Decreases Vascular Oxidative Stress, Improves Endothelial Function, and Attenuates Atherosclerosis Development in Mice.

    Frontiers in cardiovascular medicine

    Authors: Sebastian Zimmer, Philip Roger Goody, Matthias Oelze, Alexander Ghanem, Cornelius F Mueller, Ulrich Laufs, Andreas Daiber, Felix Jansen, Georg Nickenig, Sven Wassmann

  • sCD28, sCD80, sCTLA-4, and sBTLA Are Promising Markers in Diagnostic and Therapeutic Approaches for Aseptic Loosening and Periprosthetic Joint Infection.

    Frontiers in immunology

    Authors: Jil M Jubel, Thomas M Randau, Janine Becker-Gotot, Sebastian Scheidt, Matthias D Wimmer, Hendrik Kohlhof, Christof Burger, Dieter C Wirtz, Frank A Schildberg

  • ROCKing Chronic Graft-Versus-Host Disease.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    Authors: Annkristin Heine, Tobias A W Holderried, Dominik Wolf

  • Therapeutic potential of biologics in prurigo nodularis.

    Expert opinion on biological therapy

    Authors: Svenja Müller, Thomas Bieber, Sonja Ständer

  • Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Maria Embgenbroich, Hendrik J P van der Zande, Leonie Hussaarts, Jonas Schulte-Schrepping, Leonard R Pelgrom, Noemí García-Tardón, Laura Schlautmann, Isabel Stoetzel, Kristian Händler, Joost M Lambooij, Anna Zawistowska-Deniziak, Lisa Hoving, Karin de Ruiter, Marjolein Wijngaarden, Hanno Pijl, Ko Willems van Dijk, Bart Everts, Vanessa van Harmelen, Maria Yazdanbakhsh, Joachim L Schultze, Bruno Guigas, Sven Burgdorf

  • De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis.

    The EMBO journal

    Authors: Sara Zocher, Rupert W Overall, Gabriel Berdugo-Vega, Nicole Rund, Anne Karasinsky, Vijay S Adusumilli, Christina Steinhauer, Sina Scheibenstock, Kristian Händler, Joachim L Schultze, Federico Calegari, Gerd Kempermann

  • Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function.

    eLife

    Authors: Fiona Haward, Magdalena M Maslon, Patricia L Yeyati, Nicolas Bellora, Jan N Hansen, Stuart Aitken, Jennifer Lawson, Alex von Kriegsheim, Dagmar Wachten, Pleasantine Mill, Ian R Adams, Javier F Caceres

  • Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses.

    Journal of extracellular vesicles

    Authors: Christina F Budden, Linden J Gearing, Romina Kaiser, Lena Standke, Paul J Hertzog, Eicke Latz

  • promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma.

    Journal for immunotherapy of cancer

    Authors: Niklas Klümper, Damian J Ralser, Romina Zarbl, Katrin Schlack, Andres Jan Schrader, Marc Rehlinghaus, Michèle J Hoffmann, Günter Niegisch, Annemarie Uhlig, Lutz Trojan, Julie Steinestel, Konrad Steinestel, Ralph M Wirtz, Danijel Sikic, Markus Eckstein, Glen Kristiansen, Marieta Toma, Michael Hölzel, Manuel Ritter, Sebastian Strieth, Jörg Ellinger, Dimo Dietrich

  • Novel therapies and the potential for a personalized approach to atopic dermatitis.

    Current opinion in allergy and clinical immunology

    Authors: Galina Balakirski, Natalija Novak