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featured publications

  • Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes.

    The Journal of clinical investigation

    Authors: Bowen Zhang, Simone Jcfm Moorlag, Jorge Dominguez-Andres, Özlem Bulut, Gizem Kilic, Zhaoli Liu, Reinout van Crevel, Cheng-Jian Xu, Leo Ab Joosten, Mihai G Netea, Yang Li

  • Dietary recommendations for persons with type 2 diabetes mellitus.

    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association

    Authors: Thomas Skurk, Anja Bosy-Westphal, Arthur Grünerbel, Stefan Kabisch, Winfried Keuthage, Peter Kronsbein, Karsten Müssig, Andreas F H Pfeiffer, Marie-Christine Simon, Astrid Tombek, Katharina S Weber, Diana Rubin

  • Re-sequencing of candidate genes FOXF1, HSPA6, HAAO, and KYNU in 522 individuals with VATER/VACTERL, VACTER/VACTERL-like association, and isolated anorectal malformation.

    Birth defects research

    Authors: Corina E Thiem, Jil D Stegmann, Alina C Hilger, Lea Waffenschmidt, Charlotte Bendixen, Ricarda Köllges, Eberhard Schmiedeke, Frank-Mattias Schäfer, Martin Lacher, Ferdinand Kosch, Sabine Grasshoff-Derr, Carmen Kabs, Jörg Neser, Ekkehart Jenetzky, Julia Fazaal, Johannes Schumacher, Julia Hoefele, Kerstin U Ludwig, Heiko Reutter

  • Increased Prevalence of Elevated D-Dimer Levels in Patients on Direct Oral Anticoagulants: Results of a Large Retrospective Study.

    Frontiers in cardiovascular medicine

    Authors: Sara Reda, Elena Thiele Serra, Jens Müller, Nasim Shahidi Hamedani, Johannes Oldenburg, Bernd Pötzsch, Heiko Rühl

  • C-reactive protein flare predicts response to anti-PD-(L)1 immune checkpoint blockade in metastatic urothelial carcinoma.

    European journal of cancer (Oxford, England : 1990)

    Authors: Niklas Klümper, Danijel Sikic, Jonas Saal, Thomas Büttner, Franziska Goldschmidt, Jonas Jarczyk, Philippe Becker, Philip Zeuschner, Maximilian Weinke, Charis Kalogirou, Johannes Breyer, Maximilian Burger, Philipp Nuhn, Karl Tully, Florian Roghmann, Christian Bolenz, Friedemann Zengerling, Ralph M Wirtz, Michael Muders, Glen Kristiansen, Tobias Bald, Jörg Ellinger, Bernd Wullich, Michael Hölzel, Arndt Hartmann, Philipp Erben, Manuel Ritter, Markus Eckstein

  • Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis.

    GMS infectious diseases

    Authors: Alexandra Ehrens, Achim Hoerauf, Marc P Hübner

  • Inflammatory Tumor Microenvironment in Cranial Meningiomas: Clinical Implications and Intraindividual Reproducibility.

    Diagnostics (Basel, Switzerland)

    Authors: Johannes Wach, Tim Lampmann, Ági Güresir, Hartmut Vatter, Ulrich Herrlinger, Albert Becker, Marieta Toma, Michael Hölzel, Erdem Güresir

  • Impacts of NaHCO on β-Lactam Binding to PBP2a Protein Variants Associated with the NaHCO-Responsive versus NaHCO-Non-Responsive Phenotypes.

    Antibiotics (Basel, Switzerland)

    Authors: Selvi C Ersoy, Liana C Chan, Michael R Yeaman, Henry F Chambers, Richard A Proctor, Kevin C Ludwig, Tanja Schneider, Adhar C Manna, Ambrose Cheung, Arnold S Bayer

  • A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.

    Science translational medicine

    Authors: Alessandra Ghigo, Alessandra Murabito, Valentina Sala, Anna Rita Pisano, Serena Bertolini, Ambra Gianotti, Emanuela Caci, Alessio Montresor, Aiswarya Premchandar, Flora Pirozzi, Kai Ren, Angela Della Sala, Marco Mergiotti, Wito Richter, Eyleen de Poel, Michaela Matthey, Sara Caldrer, Rosa A Cardone, Federica Civiletti, Andrea Costamagna, Nancy L Quinney, Cosmin Butnarasu, Sonja Visentin, Maria Rosaria Ruggiero, Simona Baroni, Simonetta Geninatti Crich, Damien Ramel, Muriel Laffargue, Carlo G Tocchetti, Renzo Levi, Marco Conti, Xiao-Yun Lu, Paola Melotti, Claudio Sorio, Virginia De Rose, Fabrizio Facchinetti, Vito Fanelli, Daniela Wenzel, Bernd K Fleischmann, Marcus A Mall, Jeffrey Beekman, Carlo Laudanna, Martina Gentzsch, Gergely L Lukacs, Nicoletta Pedemonte, Emilio Hirsch

  • The emerging role of mass spectrometry-based proteomics in drug discovery.

    Nature reviews. Drug discovery

    Authors: Felix Meissner, Jennifer Geddes-McAlister, Matthias Mann, Marcus Bantscheff