Transmission of trained immunity and heterologous resistance to infections across generations.
Nature immunology
Authors:
Natalie Katzmarski, Jorge Domínguez-Andrés, Branko Cirovic, Georgios Renieris, Eleonora Ciarlo, Didier Le Roy, Konstantin Lepikhov, Kathrin Kattler, Gilles Gasparoni, Kristian Händler, Heidi Theis, Marc Beyer, Jos W M van der Meer, Leo A B Joosten, Jörn Walter, Joachim L Schultze, Thierry Roger, Evangelos J Giamarellos-Bourboulis, Andreas Schlitzer, Mihai G Netea
Kallikrein augments the anticoagulant function of the protein C system in thrombin generation.
Journal of thrombosis and haemostasis : JTH
Authors:
Jun Wan, Nadira Vadaq, Joke Konings, Martin Jaeger, Vinod Kumar, Bas de Laat, Leo Joosten, Mihai G Netea, Andre J van der Ven, Philip G de Groot, Quirijn de Mast, Mark Roest
The influence of the gut microbiome on BCG-induced trained immunity.
Genome biology
Authors:
Martin Stražar, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Simone J C F M Moorlag, Leo A B Joosten, Reinout van Crevel, Hera Vlamakis, Mihai G Netea, Ramnik J Xavier
Interferon gamma immunotherapy in five critically ill COVID-19 patients with impaired cellular immunity: A case series.
Med (New York, N.Y.)
Authors:
Arjan van Laarhoven, Lisa Kurver, Gijs J Overheul, Emma J Kooistra, Wilson F Abdo, Reinout van Crevel, Raphaël Duivenvoorden, Matthijs Kox, Jaap Ten Oever, Jeroen Schouten, Frank L van de Veerdonk, Hans van der Hoeven, Janette Rahamat-Langendoen, Ronald P van Rij, Peter Pickkers, Mihai G Netea
Evolution of cytokine production capacity in ancient and modern European populations.
eLife
Authors:
Jorge Domínguez-Andrés, Yunus Kuijpers, Olivier B Bakker, Martin Jaeger, Cheng-Jian Xu, Jos Wm Van der Meer, Mattias Jakobsson, Jaume Bertranpetit, Leo Ab Joosten, Yang Li, Mihai G Netea
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial.
Nature medicine
Authors:
Evdoxia Kyriazopoulou, Garyfallia Poulakou, Haralampos Milionis, Simeon Metallidis, Georgios Adamis, Konstantinos Tsiakos, Archontoula Fragkou, Aggeliki Rapti, Christina Damoulari, Massimo Fantoni, Ioannis Kalomenidis, Georgios Chrysos, Andrea Angheben, Ilias Kainis, Zoi Alexiou, Francesco Castelli, Francesco Saverio Serino, Maria Tsilika, Petros Bakakos, Emanuele Nicastri, Vassiliki Tzavara, Evangelos Kostis, Lorenzo Dagna, Panagiotis Koufargyris, Katerina Dimakou, Spyridon Savvanis, Glykeria Tzatzagou, Maria Chini, Giulio Cavalli, Matteo Bassetti, Konstantina Katrini, Vasileios Kotsis, George Tsoukalas, Carlo Selmi, Ioannis Bliziotis, Michael Samarkos, Michael Doumas, Sofia Ktena, Aikaterini Masgala, Ilias Papanikolaou, Maria Kosmidou, Dimitra-Melia Myrodia, Aikaterini Argyraki, Chiara Simona Cardellino, Katerina Koliakou, Eleni-Ioanna Katsigianni, Vassiliki Rapti, Efthymia Giannitsioti, Antonella Cingolani, Styliani Micha, Karolina Akinosoglou, Orestis Liatsis-Douvitsas, Styliani Symbardi, Nikolaos Gatselis, Maria Mouktaroudi, Giuseppe Ippolito, Eleni Florou, Antigone Kotsaki, Mihai G Netea, Jesper Eugen-Olsen, Miltiades Kyprianou, Periklis Panagopoulos, George N Dalekos, Evangelos J Giamarellos-Bourboulis