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featured publications

  • Deciphering the Therapeutic Potential of Novel Pentyloxyamide-Based Class I, IIb HDAC Inhibitors against Therapy-Resistant Leukemia.

    Journal of medicinal chemistry

    Authors: Fabian Fischer, Julian Schliehe-Diecks, Jia-Wey Tu, Tanja Gangnus, Yu Lin Ho, Mara Hebeis, Leandro A Alves Avelar, Katerina Scharov, Titus Watrin, Marie Kemkes, Pawel Stachura, Katharina Daugs, Lukas Biermann, Josefa Kremeyer, Nadine Horstick, Ingrid Span, Aleksandra A Pandyra, Arndt Borkhardt, Holger Gohlke, Matthias U Kassack, Bjoern B Burckhardt, Sanil Bhatia, Thomas Kurz

  • Rapid and motion-robust pediatric brain imaging: T2-weighted turbo-spin-echo PROPELLER acquisition with compressed sensing.

    Pediatric radiology

    Authors: Barbara Daria Wichtmann, Christoph Katemann, Mergim Kadrija, Yannik C Layer, Leon M Bischoff, Yvonne Scheuver, Madeleine Mezger, Oliver M Weber, Julian A Luetkens, Ulrike I Attenberger, Alexander Radbruch, Daniel Paech

  • Investigating the Role of Primary Cilia and Bone Morphogenetic Protein Signaling in Periodontal Ligament Response to Orthodontic Strain In Vivo and In Vitro: A Pilot Study.

    International journal of molecular sciences

    Authors: Emily R Moore, Anna Konermann

  • A Tumor Volume Segmentation Algorithm Based on Radiomics Features in FDG-PET in Lung Cancer Patients, Validated Using Surgical Specimens.

    Diagnostics (Basel, Switzerland)

    Authors: Lena Bundschuh, Jens Buermann, Marieta Toma, Joachim Schmidt, Glen Kristiansen, Markus Essler, Ralph Alexander Bundschuh, Vesna Prokic

  • Allosteric substrate release by a sialic acid TRAP transporter substrate binding protein.

    Communications biology

    Authors: Niels Schneberger, Philipp Hendricks, Martin F Peter, Erik Gehrke, Sophie C Binder, Paul-Albert Koenig, Stephan Menzel, Gavin H Thomas, Gregor Hagelueken

  • An engineered cereblon optimized for high throughput screening and molecular glue discovery.

    Cell chemical biology

    Authors: Henry J Bailey, Jonathan Eisert, Rubina Kazi, Jan Gerhartz, Dominika Ewa Pieńkowska, Ina Dressel, Joshua Vollrath, Ivan Kondratov, Tetiana Matviyuk, Nataliya Tolmachova, Varun Jayeshkumar Shah, Giulio Giuliani, Thorsten Mosler, Thomas M Geiger, Ana M Esteves, Sandra P Santos, Raquel L Sousa, Tiago M Bandeiras, Eva-Maria Leibrock, Ulrike Bauer, Birgitta Leuthner, Julian D Langer, Ansgar A Wegener, Radosław P Nowak, Fiona J Sorrell, Ivan Dikic

  • Bortezomib before and after high-dose therapy in transplant-eligible patients with newly diagnosed multiple myeloma: Long-term overall survival after more than 10 years of follow-up from the phase III HOVON-65/GMMG-HD4 trial.

    HemaSphere

    Authors: Elias K Mai, Axel Nogai, Henk M Lokhorst, Bronno van der Holt, Sonja Zweegman, Katja C Weisel, Sandra Croockewit, Anna Jauch, Jens Hillengass, Marian Stevens-Kroef, Marc S Raab, Annemiek Broijl, Gerard M J Bos, Peter Brossart, Paula Ypma, Christine Hanoun, Uta Bertsch, Thomas Hielscher, Hans J Salwender, Christoph Scheid, Hartmut Goldschmidt, Pieter Sonneveld

  • Metastasis Detection Using True and Artificial T1-Weighted Postcontrast Images in Brain MRI.

    Investigative radiology

    Authors: Robert Haase, Thomas Pinetz, Erich Kobler, Zeynep Bendella, Daniel Paech, Ralf Clauberg, Martha Foltyn-Dumitru, Verena Wagner, Kai Schlamp, Gudula Heussel, Claus Peter Heussel, Martin Vahlensieck, Julian A Luetkens, Heinz-Peter Schlemmer, Louisa Specht-Riemenschneider, Alexander Radbruch, Alexander Effland, Katerina Deike

  • Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response.

    Cell reports. Medicine

    Authors: Rachel Brandes-Leibovitz, Anca Riza, Gal Yankovitz, Andrei Pirvu, Stefania Dorobantu, Adina Dragos, Ioana Streata, Isis Ricaño-Ponce, Aline de Nooijer, Florentina Dumitrescu, Nikolaos Antonakos, Eleni Antoniadou, George Dimopoulos, Ioannis Koutsodimitropoulos, Theano Kontopoulou, Dimitra Markopoulou, Eleni Aimoniotou, Apostolos Komnos, George N Dalekos, Mihai Ioana, Evangelos J Giamarellos-Bourboulis, Irit Gat-Viks, Mihai G Netea

  • The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors.

    British journal of pharmacology

    Authors: Tom Teichmann, Beatrice Pflüger-Müller, Virna Margarita Martín Giménez, Fiona Sailer, Henrik Dirks, Simonida Zehr, Timothy Warwick, Felix Brettner, Paola Munoz-Tello, Andreas Zimmer, Irmgard Tegeder, Dominique Thomas, Robert Gurke, Stefan Günther, Jan Heering, Ewgenij Proschak, Gerd Geisslinger, Iris-S Bibli, Dagmar Meyer Zu Heringdorf, Walter Manucha, Maike Windbergs, Stefan Knapp, Andreas Weigert, Matthias S Leisegang, Douglas Kojetin, Ralf P Brandes