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featured publications

  • Heparin-Induced Thrombocytopenia in Patients Suffering Cardiogenic Shock.

    Critical care explorations

    Authors: Enzo Lüsebrink, Hugo Lanz, Leonhard Binzenhöfer, Sabine Hoffmann, Julia Höpler, Marie Kraft, Nils Gade, Jonas Gmeiner, Daniel Roden, Inas Saleh, Christian Hagl, Georg Nickenig, Steffen Massberg, Sebastian Zimmer, Raúl Nicolás Jamin, Clemens Scherer

  • Next-generation phenotyping integrated in a national framework for patients with ultrarare disorders improves genetic diagnostics and yields new molecular findings.

    Nature genetics

    Authors: Axel Schmidt, Magdalena Danyel, Kathrin Grundmann, Theresa Brunet, Hannah Klinkhammer, Tzung-Chien Hsieh, Hartmut Engels, Sophia Peters, Alexej Knaus, Shahida Moosa, Luisa Averdunk, Felix Boschann, Henrike Lisa Sczakiel, Sarina Schwartzmann, Martin Atta Mensah, Jean Tori Pantel, Manuel Holtgrewe, Annemarie Bösch, Claudia Weiß, Natalie Weinhold, Aude-Annick Suter, Corinna Stoltenburg, Julia Neugebauer, Tillmann Kallinich, Angela M Kaindl, Susanne Holzhauer, Christoph Bührer, Philip Bufler, Uwe Kornak, Claus-Eric Ott, Markus Schülke, Hoa Huu Phuc Nguyen, Sabine Hoffjan, Corinna Grasemann, Tobias Rothoeft, Folke Brinkmann, Nora Matar, Sugirthan Sivalingam, Claudia Perne, Elisabeth Mangold, Martina Kreiss, Kirsten Cremer, Regina C Betz, Martin Mücke, Lorenz Grigull, Thomas Klockgether, Isabel Spier, André Heimbach, Tim Bender, Fabian Brand, Christiane Stieber, Alexandra Marzena Morawiec, Pantelis Karakostas, Valentin S Schäfer, Sarah Bernsen, Patrick Weydt, Sergio Castro-Gomez, Ahmad Aziz, Marcus Grobe-Einsler, Okka Kimmich, Xenia Kobeleva, Demet Önder, Hellen Lesmann, Sheetal Kumar, Pawel Tacik, Meghna Ahuja Basin, Pietro Incardona, Min Ae Lee-Kirsch, Reinhard Berner, Catharina Schuetz, Julia Körholz, Tanita Kretschmer, Nataliya Di Donato, Evelin Schröck, André Heinen, Ulrike Reuner, Amalia-Mihaela Hanßke, Frank J Kaiser, Eva Manka, Martin Munteanu, Alma Kuechler, Kiewert Cordula, Raphael Hirtz, Elena Schlapakow, Christian Schlein, Jasmin Lisfeld, Christian Kubisch, Theresia Herget, Maja Hempel, Christina Weiler-Normann, Kurt Ullrich, Christoph Schramm, Cornelia Rudolph, Franziska Rillig, Maximilian Groffmann, Ania Muntau, Alexandra Tibelius, Eva M C Schwaibold, Christian P Schaaf, Michal Zawada, Lilian Kaufmann, Katrin Hinderhofer, Pamela M Okun, Urania Kotzaeridou, Georg F Hoffmann, Daniela Choukair, Markus Bettendorf, Malte Spielmann, Annekatrin Ripke, Martje Pauly, Alexander Münchau, Katja Lohmann, Irina Hüning, Britta Hanker, Tobias Bäumer, Rebecca Herzog, Yorck Hellenbroich, Dominik S Westphal, Tim Strom, Reka Kovacs, Korbinian M Riedhammer, Katharina Mayerhanser, Elisabeth Graf, Melanie Brugger, Julia Hoefele, Konrad Oexle, Nazanin Mirza-Schreiber, Riccardo Berutti, Ulrich Schatz, Martin Krenn, Christine Makowski, Heike Weigand, Sebastian Schröder, Meino Rohlfs, Katharina Vill, Fabian Hauck, Ingo Borggraefe, Wolfgang Müller-Felber, Ingo Kurth, Miriam Elbracht, Cordula Knopp, Matthias Begemann, Florian Kraft, Johannes R Lemke, Julia Hentschel, Konrad Platzer, Vincent Strehlow, Rami Abou Jamra, Martin Kehrer, German Demidov, Stefanie Beck-Wödl, Holm Graessner, Marc Sturm, Lena Zeltner, Ludger J Schöls, Janine Magg, Andrea Bevot, Christiane Kehrer, Nadja Kaiser, Ernest Turro, Denise Horn, Annette Grüters-Kieslich, Christoph Klein, Stefan Mundlos, Markus Nöthen, Olaf Riess, Thomas Meitinger, Heiko Krude, Peter M Krawitz, Tobias Haack, Nadja Ehmke, Matias Wagner

  • Sex-specific epigenetic signatures of circulating urate and its increase after BCG vaccination.

    Research square

    Authors: Zhaoli Liu, Tania O Crișan, Cancan Qi, Manoj Kumar Gupta, Xuan Liu, Simone J C F M Moorlag, Valerie A C M Koeken, L Charlotte J de Bree, Vera P Mourits, Xu Gao, Andrea Baccarelli, Joel Schwartz, Frank Pessler, Carlos A Guzmán, Yang Li, Mihai G Netea, Leo A B Joosten, Cheng-Jian Xu

  • A nonsense variant in KRT31 is associated with autosomal-dominant monilethrix.

    The British journal of dermatology

    Authors: Xing Xiong, Nicole Cesarato, Yasmina Gossmann, Maria Wehner, Sheetal Kumar, Holger Thiele, Stephanie Demuth, Vinzenz Oji, Matthias Geyer, Henning Hamm, F Buket Basmanav, Regina C Betz

  • Peripheral whole blood microRNA expression in relation to vascular function: a population-based study.

    Journal of translational medicine

    Authors: Valentina Talevi, Konstantinos Melas, Gökhan Pehlivan, Mohammed A Imtiaz, Dennis Manfred Krüger, Tonatiuh Pena Centeno, N Ahmad Aziz, Andre Fischer, Monique M B Breteler

  • Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system.

    Immunity

    Authors: Vini Tiwari, Bharat Prajapati, Yaw Asare, Alkmini Damkou, Hao Ji, Lu Liu, Nawraa Naser, Garyfallia Gouna, Katarzyna B Leszczyńska, Jakub Mieczkowski, Martin Dichgans, Qing Wang, Riki Kawaguchi, Zechuan Shi, Vivek Swarup, Daniel H Geschwind, Marco Prinz, Ozgun Gokce, Mikael Simons

  • IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer.

    Nature communications

    Authors: Lies van Baarle, Veronica De Simone, Linda Schneider, Sneha Santhosh, Saeed Abdurahiman, Francesca Biscu, Reiner Schneider, Lisa Zanoletti, Renata Siqueira de Mello, Sara Verbandt, Zedong Hu, Michelle Stakenborg, Bo-Jun Ke, Nathalie Stakenborg, Raquel Salvador Laureano, Balbina García-Reyes, Jonas Henn, Marieta Toma, Maxime Vanmechelen, Guy Boeckxstaens, Frederik De Smet, Abhishek D Garg, Sales Ibiza, Sabine Tejpar, Sven Wehner, Gianluca Matteoli

  • Synthetic RIG-I agonist-mediated cancer immunotherapy synergizes with MAP kinase inhibition against BRAF-mutated melanoma.

    Molecular therapy. Nucleic acids

    Authors: Christian Grützner, Yu Pan Tan, Patrick Müller, Thais M Schlee-Guimaraes, Marius Jentzsch, Jonathan L Schmid-Burgk, Marcel Renn, Rayk Behrendt, Gunther Hartmann

  • Endovascular treatment of primary M3 occlusion stroke in clinical practice: analysis of the German Stroke Registry.

    Neurological research and practice

    Authors: Niklas M Beckonert, Johannes M Weller, Anna C Alegiani, Tobias Boeckh-Behrens, Milani Deb-Chatterji, Gerhard F Hamann, Lars U Krause, Nils C Lehnen, Louisa Nitsch, Sven Poli, Christian Riedel, Steffen Tiedt, Sarah Zweynert, Gabor C Petzold, Franziska Dorn, Felix J Bode

  • extracellular replication of endobacteria.

    Frontiers in microbiology

    Authors: Lara Vanessa Behrmann, Kirstin Meier, Jennifer Vollmer, Chukwuebuka Chibuzo Chiedu, Andrea Schiefer, Achim Hoerauf, Kenneth Pfarr