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  • Viral RNA recognition by LGP2 and MDA5, and activation of signaling through step-by-step conformational changes.

    Nucleic acids research

    Authors: Ivana Duic, Hisashi Tadakuma, Yoshie Harada, Ryo Yamaue, Katashi Deguchi, Yuki Suzuki, Shige H Yoshimura, Hiroki Kato, Kunio Takeyasu, Takashi Fujita

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  • Blood Metabolomic Profiling Confirms and Identifies Biomarkers of Food Intake.

    Metabolites

    Authors: Julia Langenau, Kolade Oluwagbemigun, Christian Brachem, Wolfgang Lieb, Romina di Giuseppe, Anna Artati, Gabi Kastenmüller, Leonie Weinhold, Matthias Schmid, Ute Nöthlings

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  • BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils.

    Cell reports

    Authors: Simone J C F M Moorlag, Yessica Alina Rodriguez-Rosales, Joshua Gillard, Stephanie Fanucchi, Kate Theunissen, Boris Novakovic, Cynthia M de Bont, Yutaka Negishi, Ezio T Fok, Lydia Kalafati, Panayotis Verginis, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Ger J M Pruijn, Craig Fenwick, Reinout van Crevel, Leo A B Joosten, Irma Joosten, Hans Koenen, Musa M Mhlanga, Dimitri A Diavatopoulos, Triantafyllos Chavakis, Mihai G Netea

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  • Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany.

    Nature communications

    Authors: Hendrik Streeck, Bianca Schulte, Beate M Kümmerer, Enrico Richter, Tobias Höller, Christine Fuhrmann, Eva Bartok, Ramona Dolscheid-Pommerich, Moritz Berger, Lukas Wessendorf, Monika Eschbach-Bludau, Angelika Kellings, Astrid Schwaiger, Martin Coenen, Per Hoffmann, Birgit Stoffel-Wagner, Markus M Nöthen, Anna M Eis-Hübinger, Martin Exner, Ricarda Maria Schmithausen, Matthias Schmid, Gunther Hartmann

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  • CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab).

    Cancer immunology, immunotherapy : CII

    Authors: Simon Fietz, Romina Zarbl, Dennis Niebel, Christian Posch, Peter Brossart, Gerrit H Gielen, Sebastian Strieth, Torsten Pietsch, Glen Kristiansen, Friedrich Bootz, Jennifer Landsberg, Dimo Dietrich

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  • Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs.

    Molecular cell

    Authors: Eva Marie Pfeil, Julian Brands, Nicole Merten, Timo Vögtle, Maddalena Vescovo, Ulrike Rick, Ina-Maria Albrecht, Nina Heycke, Kouki Kawakami, Yuki Ono, Francois Marie Ngako Kadji, Suzune Hiratsuka, Junken Aoki, Felix Häberlein, Michaela Matthey, Jaspal Garg, Stephanie Hennen, Marie-Lise Jobin, Kerstin Seier, Davide Calebiro, Alexander Pfeifer, Akos Heinemann, Daniela Wenzel, Gabriele M König, Bernhard Nieswandt, Bernd K Fleischmann, Asuka Inoue, Katharina Simon, Evi Kostenis

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  • Analogous modulation of inflammatory responses by the endocannabinoid system in periodontal ligament cells and microglia.

    Head & face medicine

    Authors: Andreas Jäger, Maria Setiawan, Eva Beins, Ingo Schmidt-Wolf, Anna Konermann

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  • Extended Half-Life Factor VIII/Factor IX Products: Assay Discrepancies and Implications for Hemophilia Management.

    Hamostaseologie

    Authors: Jens Müller, Georg Goldmann, Natascha Marquardt, Bernd Pötzsch, Johannes Oldenburg

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  • Molecular Profiling of Liver Sinusoidal Endothelial Cells in Comparison to Hepatocytes: Reflection on Which Cell Type Should Be the Target for Gene Therapy.

    Hamostaseologie

    Authors: Osman El-Maarri, Muhammad Ahmer Jamil, Johannes Oldenburg

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  • Induction of cytotoxic effector cells towards cholangiocellular, pancreatic, and colorectal tumor cells by activation of the immune checkpoint CD40/CD40L on dendritic cells.

    Cancer immunology, immunotherapy : CII

    Authors: Farsaneh Sadeghlar, Annabelle Vogt, Raphael U Mohr, Robert Mahn, Katrin van Beekum, Miroslaw Kornek, Tobias J Weismüller, Vittorio Branchi, Hanno Matthaei, Marieta Toma, I G H Schmidt-Wolf, Jörg C Kalff, Christian P Strassburg, Maria A González-Carmona

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