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Publications

featured publications

  • Untargeted Plasma Metabolomics and Gut Microbiome Profiling Provide Novel Insights into the Regulation of Platelet Reactivity in Healthy Individuals.

    Thrombosis and haemostasis

    Authors: Nadira Vadaq, Melanie Schirmer, Rahajeng N Tunjungputri, Hera Vlamakis, Cecilia Chiriac, Edwin Ardiansyah, M Hussein Gasem, Leo A B Joosten, Philip G de Groot, Ramnik J Xavier, Mihai G Netea, Andre J van der Ven, Quirijn de Mast

  • An Explorative Study on Monocyte Reprogramming in the Context of Periodontitis and .

    Frontiers in immunology

    Authors: Marlies P Noz, Adelina S Plachokova, Esther M M Smeets, Erik H J G Aarntzen, Siroon Bekkering, Prya Vart, Leo A B Joosten, Mihai G Netea, Niels P Riksen

  • The Immunological Factors Predisposing to Severe Covid-19 Are Already Present in Healthy Elderly and Men.

    Frontiers in immunology

    Authors: Gizem Kilic, Ozlem Bulut, Martin Jaeger, Rob Ter Horst, Valerie A C M Koeken, Simone J C F M Moorlag, Vera P Mourits, Charlotte de Bree, Jorge Domínguez-Andrés, Leo A B Joosten, Mihai G Netea

  • Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19.

    Bioscience reports

    Authors: Aline H de Nooijer, Inge Grondman, Simon Lambden, Emma J Kooistra, Nico A F Janssen, Matthijs Kox, Peter Pickkers, Leo A B Joosten, Frank L van de Veerdonk, Marc Derive, Sebastien Gibot, Mihai G Netea

  • Challenges and Opportunities in Understanding Genetics of Fungal Diseases: Towards a Functional Genomics Approach.

    Infection and immunity

    Authors: Mariolina Bruno, Vasiliki Matzaraki, Frank L van de Veerdonk, Vinod Kumar, Mihai G Netea

  • Seasonal and Nonseasonal Longitudinal Variation of Immune Function.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Rob Ter Horst, Martin Jaeger, Lisa van de Wijer, Wouter A van der Heijden, Anna M W Janssen, Sanne P Smeekens, Michelle A E Brouwer, Bram van Cranenbroek, Raul Aguirre-Gamboa, Romana T Netea-Maier, Antonius E van Herwaarden, Heidi Lemmers, Helga Dijkstra, Irma Joosten, Hans Koenen, Mihai G Netea, Leo A B Joosten

  • Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis.

    Circulation

    Authors: Laurienne Edgar, Naveed Akbar, Adam T Braithwaite, Thomas Krausgruber, Héctor Gallart-Ayala, Jade Bailey, Alastair L Corbin, Tariq E Khoyratty, Joshua T Chai, Mohammad Alkhalil, André F Rendeiro, Klemen Ziberna, Ritu Arya, Thomas J Cahill, Christoph Bock, Jurga Laurencikiene, Mark J Crabtree, Madeleine E Lemieux, Niels P Riksen, Mihai G Netea, Craig E Wheelock, Keith M Channon, Mikael Rydén, Irina A Udalova, Ricardo Carnicer, Robin P Choudhury

  • Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4 T Cell Activation and Control.

    mBio

    Authors: Shibali Das, Nancy D Marin, Ekaterina Esaulova, Mushtaq Ahmed, Amanda Swain, Bruce A Rosa, Makedonka Mitreva, Javier Rangel-Moreno, Mihai G Netea, Luis B Barreiro, Maziar Divangahi, Maxim N Artyomov, Deepak Kaushal, Shabaana A Khader

  • Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation .

    Frontiers in immunology

    Authors: Asimenia Angelidou, Joann Diray-Arce, Maria-Giulia Conti, Mihai G Netea, Bastiaan A Blok, Mark Liu, Guzman Sanchez-Schmitz, Al Ozonoff, Simon D van Haren, Ofer Levy

  • Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.

    Genome biology

    Authors: Xiaojing Chu, Martin Jaeger, Joep Beumer, Olivier B Bakker, Raul Aguirre-Gamboa, Marije Oosting, Sanne P Smeekens, Simone Moorlag, Vera P Mourits, Valerie A C M Koeken, Charlotte de Bree, Trees Jansen, Ian T Mathews, Khoi Dao, Mahan Najhawan, Jeramie D Watrous, Irma Joosten, Sonia Sharma, Hans J P M Koenen, Sebo Withoff, Iris H Jonkers, Romana T Netea-Maier, Ramnik J Xavier, Lude Franke, Cheng-Jian Xu, Leo A B Joosten, Serena Sanna, Mohit Jain, Vinod Kumar, Hans Clevers, Cisca Wijmenga, Mihai G Netea, Yang Li