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  • Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.

    Nature metabolism

    Authors: Wei He, Antonia Henne, Mario Lauterbach, Eike Geißmar, Fabian Nikolka, Celia Kho, Alexander Heinz, Catherine Dostert, Melanie Grusdat, Thekla Cordes, Janika Härm, Oliver Goldmann, Anouk Ewen, Charlène Verschueren, Julia Blay-Cadanet, Robert Geffers, Hendrikus Garritsen, Manfred Kneiling, Christian K Holm, Christian M Metallo, Eva Medina, Zeinab Abdullah, Eicke Latz, Dirk Brenner, Karsten Hiller

  • The impact of pre-existing thyroid diseases on susceptibility to respiratory infections or self-reported sickness during the SARS-CoV-2 pandemic.

    Archives of endocrinology and metabolism

    Authors: Maartje A J Rops, Simone J C F M Moorlag, Rosanne C van Deuren, Martin Jaeger, Leo A B Joosten, Marco Medici, Mihai G Netea, Jan W A Smit, Romana T Netea-Maier

  • The form of PEG matters: PEG conjugated with lipids and not PEG alone could be the specific form involved in allergic reactions to COVID-19 vaccines.

    Allergy

    Authors: Beatriz Cabanillas, Natalija Novak, Cezmi A Akdis

  • The GA4GH Phenopacket schema defines a computable representation of clinical data.

    Nature biotechnology

    Authors: Julius O B Jacobsen, Michael Baudis, Gareth S Baynam, Jacques S Beckmann, Sergi Beltran, Orion J Buske, Tiffany J Callahan, Christopher G Chute, Mélanie Courtot, Daniel Danis, Olivier Elemento, Andrea Essenwanger, Robert R Freimuth, Michael A Gargano, Tudor Groza, Ada Hamosh, Nomi L Harris, Rajaram Kaliyaperumal, Kevin C Kent Lloyd, Aly Khalifa, Peter M Krawitz, Sebastian Köhler, Brian J Laraway, Heikki Lehväslaiho, Leslie Matalonga, Julie A McMurry, Alejandro Metke-Jimenez, Christopher J Mungall, Monica C Munoz-Torres, Soichi Ogishima, Anastasios Papakonstantinou, Davide Piscia, Nikolas Pontikos, Núria Queralt-Rosinach, Marco Roos, Julian Sass, Paul N Schofield, Dominik Seelow, Anastasios Siapos, Damian Smedley, Lindsay D Smith, Robin Steinhaus, Jagadish Chandrabose Sundaramurthi, Emilia M Swietlik, Sylvia Thun, Nicole A Vasilevsky, Alex H Wagner, Jeremy L Warner, Claus Weiland, Melissa A Haendel, Peter N Robinson

  • Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity.

    Journal for immunotherapy of cancer

    Authors: Beatrice Thier, Fang Zhao, Simone Stupia, Alicia Brüggemann, Johannes Koch, Nina Schulze, Susanne Horn, Christoph Coch, Gunther Hartmann, Antje Sucker, Dirk Schadendorf, Annette Paschen

  • Smart devices resulting in big effect: can apps cure heart disease?

    European heart journal

    Authors: Irina Eckardt, Philip Düsing, Georg Nickenig, Felix Jansen

  • Phänotypische Vielfalt bei Varianten im TP63-Gen.

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    Authors: Ariane Schmetz, Xing Xiong, Nicole Cesarato, Fitnat Buket Basmanav, Petra Gierthmuehlen, Jörg Schaper, Daniel Schlieper, Maria Wehner, Holger Thiele, Jorge Frank, Regina C Betz, Silke Redler

  • A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes.

    eLife

    Authors: Xiaojing Chu, Anna W M Janssen, Hans Koenen, Linzhung Chang, Xuehui He, Irma Joosten, Rinke Stienstra, Yunus Kuijpers, Cisca Wijmenga, Cheng-Jian Xu, Mihai G Netea, Cees J Tack, Yang Li

  • Single cell versus single nucleus: transcriptome differences in the murine kidney after ischemia-reperfusion injury.

    American journal of physiology. Renal physiology

    Authors: Svenja Gaedcke, Julius Sinning, Oliver Dittrich-Breiholz, Hermann Haller, Inga Soerensen-Zender, Chieh Ming Liao, Alexandra Nordlohne, Payel Sen, Sibylle von Vietinghoff, David S DeLuca, Roland Schmitt

  • SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients.

    Scientific reports

    Authors: Lisa Kurver, Corné H van den Kieboom, Kjerstin Lanke, Dimitri A Diavatopoulos, Gijs J Overheul, Mihai G Netea, Jaap Ten Oever, Reinout van Crevel, Karin Mulders-Manders, Frank L van de Veerdonk, Heiman Wertheim, Jeroen Schouten, Janette Rahamat-Langendoen, Ronald P van Rij, Teun Bousema, Arjan van Laarhoven, Marien I de Jonge