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featured publications

  • Topical application of a CCL22-binding aptamer suppresses contact allergy.

    Molecular therapy. Nucleic acids

    Authors: Anna Jonczyk, Marlene Gottschalk, Matthew S J Mangan, Yasmin Majlesain, Manja W Thiem, Lea-Corinna Burbaum, Heike Weighardt, Eicke Latz, Günter Mayer, Irmgard Förster

  • Legacy of the discovery of the T-cell receptor: 40 years of shaping basic immunology and translational work to develop novel therapies.

    Cellular & molecular immunology

    Authors: Yufang Shi, Andreas Strasser, Douglas R Green, Eicke Latz, Alberto Mantovani, Gerry Melino

  • Top publication

    From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.

    Scientific data

    Authors: Lea Seep, Stephan Grein, Iva Splichalova, Danli Ran, Mickel Mikhael, Staffan Hildebrand, Mario Lauterbach, Karsten Hiller, Dalila Juliana Silva Ribeiro, Katharina Sieckmann, Ronja Kardinal, Hao Huang, Jiangyan Yu, Sebastian Kallabis, Janina Behrens, Andreas Till, Viktoriya Peeva, Akim Strohmeyer, Johanna Bruder, Tobias Blum, Ana Soriano-Arroquia, Dominik Tischer, Katharina Kuellmer, Yuanfang Li, Marc Beyer, Anne-Kathrin Gellner, Tobias Fromme, Henning Wackerhage, Martin Klingenspor, Wiebke K Fenske, Ludger Scheja, Felix Meissner, Andreas Schlitzer, Elvira Mass, Dagmar Wachten, Eicke Latz, Alexander Pfeifer, Jan Hasenauer

  • Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.

    Nature

    Authors: Jean-Philippe Auger, Max Zimmermann, Maria Faas, Ulrich Stifel, David Chambers, Brenda Krishnacoumar, R Verena Taudte, Charlotte Grund, Gitta Erdmann, Carina Scholtysek, Stefan Uderhardt, Oumaima Ben Brahim, Mónica Pascual Maté, Cornelia Stoll, Martin Böttcher, Katrin Palumbo-Zerr, Matthew S J Mangan, Maria Dzamukova, Markus Kieler, Melanie Hofmann, Stephan Blüml, Gernot Schabbauer, Dimitrios Mougiakakos, Uwe Sonnewald, Fabian Hartmann, David Simon, Arnd Kleyer, Anika Grüneboom, Susetta Finotto, Eicke Latz, Jörg Hofmann, Georg Schett, Jan Tuckermann, Gerhard Krönke

  • NLRP3 inflammasome signalling in Alzheimer's disease.

    Neuropharmacology

    Authors: Róisín M McManus, Eicke Latz

  • SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.

    Nature communications

    Authors: Jakob Hartmann, Thomas Bajaj, Joy Otten, Claudia Klengel, Tim Ebert, Anne-Kathrin Gellner, Ellen Junglas, Kathrin Hafner, Elmira A Anderzhanova, Fiona Tang, Galen Missig, Lindsay Rexrode, Daniel T Trussell, Katelyn X Li, Max L Pöhlmann, Sarah Mackert, Thomas M Geiger, Daniel E Heinz, Roy Lardenoije, Nina Dedic, Kenneth M McCullough, Tomasz Próchnicki, Thomas Rhomberg, Silvia Martinelli, Antony Payton, Andrew C Robinson, Valentin Stein, Eicke Latz, William A Carlezon, Felix Hausch, Mathias V Schmidt, Chris Murgatroyd, Sabina Berretta, Torsten Klengel, Harry Pantazopoulos, Kerry J Ressler, Nils C Gassen

  • Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model.

    Cell reports

    Authors: Brendon D Parsons, Daniel Medina-Luna, Michal Scur, Marinella Pinelli, Gayani S Gamage, Rebecca A Chilvers, Yannick Hamon, Ibrahim H I Ahmed, Stéphane Savary, Andrew P Makrigiannis, Nancy E Braverman, Juan F Rodriguez-Alcazar, Eicke Latz, Tobias K Karakach, Francesca Di Cara

  • Cholesterol Crystal Dissolution Rate of Serum Predicts Outcomes in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.

    Journal of the American Heart Association

    Authors: Baravan Al-Kassou, Lara Al-Kassou, Thorsten Mahn, Dieter Lütjohann, Jasmin Shamekhi, Nicola Willemsen, Sven Thomas Niepmann, Stephan Baldus, Malte Kelm, Georg Nickenig, Eicke Latz, Sebastian Zimmer

  • UNC93B1 variants underlie TLR7-dependent autoimmunity.

    Science immunology

    Authors: Christine Wolf, Ee Lyn Lim, Mohammad Mokhtari, Barbara Kind, Alexandru Odainic, Eusebia Lara-Villacanas, Sarah Koss, Simon Mages, Katharina Menzel, Kerstin Engel, Gregor Dückers, Benedikt Bernbeck, Dominik T Schneider, Kathrin Siepermann, Tim Niehues, Carl Christoph Goetzke, Pawel Durek, Kirsten Minden, Thomas Dörner, Anna Stittrich, Franziska Szelinski, Gabriela Maria Guerra, Mona Massoud, Markus Bieringer, Carina C de Oliveira Mann, Eduardo Beltrán, Tilmann Kallinich, Mir-Farzin Mashreghi, Susanne V Schmidt, Eicke Latz, Johanna Klughammer, Olivia Majer, Min Ae Lee-Kirsch

  • Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 2: Assessing Inflammasome Activation.

    Methods in molecular biology (Clifton, N.J.)

    Authors: Marta Lovotti, Matthew S J Mangan, Róisín M McManus, Kateryna Shkarina, Matilde B Vasconcelos, Eicke Latz