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featured publications

  • Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq.

    Cell reports methods

    Authors: Caterina Carraro, Lorenzo Bonaguro, Rachana Srinivasa, Martina van Uelft, Victoria Isakzai, Jonas Schulte-Schrepping, Prerna Gambhir, Tarek Elmzzahi, Jessica V Montgomery, Hannah Hayer, Yuanfang Li, Heidi Theis, Michael Kraut, Krishnaa T Mahbubani, Anna C Aschenbrenner, Ireen König, Eugenio Fava, Hans-Ulrich Fried, Elena De Domenico, Marc Beyer, Adem Saglam, Joachim L Schultze

  • Identification of the novel FOXP3-dependent T cell transcription factor MEOX1 by high-dimensional analysis of human CD4 T cells.

    Frontiers in immunology

    Authors: Kevin Baßler, Lisa Schmidleithner, Mehrnoush Hadaddzadeh Shakiba, Tarek Elmzzahi, Maren Köhne, Stefan Floess, Rebekka Scholz, Naganari Ohkura, Timothy Sadlon, Kathrin Klee, Anna Neubauer, Shimon Sakaguchi, Simon C Barry, Jochen Huehn, Lorenzo Bonaguro, Thomas Ulas, Marc Beyer

  • Top publication

    Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.

    Cell reports

    Authors: Theodore S Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C Schaar, Lorenzo Bonaguro, Tal Pecht, Izabela Galvao, Shobhit Agrawal, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena de Domenico, Arik Horne, Chantal Donovan, Richard Y Kim, David Gallego-Ortega, Tessa E Gillett, Meshal Ansari, Jonas Schulte-Schrepping, Nina Offermann, Ignazio Antignano, Burcu Sivri, Wenying Lu, Mathew S Eapen, Martina van Uelft, Collins Osei-Sarpong, Maarten van den Berge, Hylke C Donker, Harry J M Groen, Sukhwinder S Sohal, Johanna Klein, Tina Schreiber, Andreas Feißt, Ali Önder Yildirim, Herbert B Schiller, Martijn C Nawijn, Matthias Becker, Kristian Händler, Marc Beyer, Melania Capasso, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Fabian J Theis, Philip M Hansbro, Dirk Skowasch, Joachim L Schultze

  • Parallel recovery of chromatin accessibility and gene expression dynamics from frozen human regulatory T cells.

    Scientific reports

    Authors: Ying Y Wong, Jessica E Harbison, Christopher M Hope, Batjargal Gundsambuu, Katherine A Brown, Soon W Wong, Cheryl Y Brown, Jennifer J Couper, Jimmy Breen, Ning Liu, Stephen M Pederson, Maren Köhne, Kathrin Klee, Joachim Schultze, Marc Beyer, Timothy Sadlon, Simon C Barry

  • Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates.

    eLife

    Authors: Niels J M Verstegen, Sabrina Pollastro, Peter-Paul A Unger, Casper Marsman, George Elias, Tineke Jorritsma, Marij Streutker, Kevin Bassler, Kristian Haendler, Theo Rispens, Joachim L Schultze, Anja Ten Brinke, Marc Beyer, S Marieke van Ham

  • Top publication

    Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.

    Journal of hepatology

    Authors: Carl-Philipp Hackstein, Jasper Spitzer, Konstantinos Symeonidis, Helena Horvatic, Tanja Bedke, Babett Steglich, Sabine Klein, Lisa M Assmus, Alexandru Odainic, Jennifer Szlapa, Nina Kessler, Marc Beyer, Ricarda Schmithausen, Eicke Latz, Richard A Flavell, Natalio Garbi, Christian Kurts, Beate M Kümmerer, Jonel Trebicka, Axel Roers, Samuel Huber, Susanne V Schmidt, Percy A Knolle, Zeinab Abdullah

  • Lung T cell response in COVID-19.

    Frontiers in immunology

    Authors: Mehrnoush Hadaddzadeh Shakiba, Ioanna Gemünd, Marc Beyer, Lorenzo Bonaguro

  • Circuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase.

    Cell reports

    Authors: Pedro Royero, Anne Quatraccioni, Rieke Früngel, Mariella Hurtado Silva, Arco Bast, Thomas Ulas, Marc Beyer, Thoralf Opitz, Joachim L Schultze, Mark E Graham, Marcel Oberlaender, Albert Becker, Susanne Schoch, Heinz Beck

  • A guide to systems-level immunomics.

    Nature immunology

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Thomas Ulas, Anna C Aschenbrenner, Marc Beyer, Joachim L Schultze

  • Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation.

    Frontiers in immunology

    Authors: Kevin Baßler, Wataru Fujii, Theodore S Kapellos, Erika Dudkin, Nico Reusch, Ari Horne, Benedikt Reiz, Malte D Luecken, Collins Osei-Sarpong, Stefanie Warnat-Herresthal, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Allon Wagner, Patrick Günther, Carmen Pizarro, Tina Schreiber, Rainer Knoll, Lisa Holsten, Charlotte Kröger, Elena De Domenico, Matthias Becker, Kristian Händler, Christian T Wohnhaas, Florian Baumgartner, Meike Köhler, Heidi Theis, Michael Kraut, Marc H Wadsworth, Travis K Hughes, Humberto J Ferreira, Emily Hinkley, Ines H Kaltheuner, Matthias Geyer, Christoph Thiele, Alex K Shalek, Andreas Feißt, Daniel Thomas, Henning Dickten, Marc Beyer, Patrick Baum, Nir Yosef, Anna C Aschenbrenner, Thomas Ulas, Jan Hasenauer, Fabian J Theis, Dirk Skowasch, Joachim L Schultze