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  • Stimulation of Immune Checkpoint Molecule B and T-Lymphocyte Attenuator Alleviates Experimental Crescentic Glomerulonephritis.

    Journal of the American Society of Nephrology : JASN

    Authors: Paul Diefenhardt, Marie Braumann, Thomas Schömig, Bastian Trinsch, Claudio Sierra Gonzalez, Janine Becker-Gotot, Linus A Völker, Lioba Ester, Amrei M Mandel, Daniel Hawiger, Ali T Abdallah, Bernhard Schermer, Heike Göbel, Paul Brinkkötter, Christian Kurts, Thomas Benzing, Sebastian Brähler

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    Fate mapping reveals compartment-specific clonal expansion of mononuclear phagocytes during kidney disease.

    Kidney international

    Authors: Junping Yin, Qi Mei, Marco Prinz, Zeinab Abdullah, Ulf Panzer, Jian Li, Sibylle von Vietinghoff, Christian Kurts

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  • CD4 T cell calibration of antigen-presenting cells optimizes antiviral CD8 T cell immunity.

    Nature immunology

    Authors: Elise Gressier, Jonas Schulte-Schrepping, Lev Petrov, Sophia Brumhard, Paula Stubbemann, Anna Hiller, Benedikt Obermayer, Jasper Spitzer, Tomislav Kostevc, Paul G Whitney, Annabell Bachem, Alexandru Odainic, Carolien van de Sandt, Thi H O Nguyen, Thomas Ashhurst, Kayla Wilson, Clare V L Oates, Linden J Gearing, Tina Meischel, Katharina Hochheiser, Marie Greyer, Michele Clarke, Maike Kreutzenbeck, Sarah S Gabriel, Wolfgang Kastenmüller, Christian Kurts, Sarah L Londrigan, Axel Kallies, Katherine Kedzierska, Paul J Hertzog, Eicke Latz, Yu-Chen E Chen, Kristen J Radford, Michael Chopin, Jan Schroeder, Florian Kurth, Thomas Gebhardt, Leif E Sander, Birgit Sawitzki, Joachim L Schultze, Susanne V Schmidt, Sammy Bedoui

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  • Kidney medullary sodium chloride concentrations induce neutrophil and monocyte extracellular DNA traps that defend against pyelonephritis in vivo.

    Kidney international

    Authors: Adrian Goldspink, Jessica Schmitz, Olena Babyak, Nicolas Brauns, Julia Milleck, Anne M Breloh, Susanne V Fleig, Katarzyna Jobin, Lisa Schwarz, Hermann Haller, Florian Wagenlehner, Jan Hinrich Bräsen, Christian Kurts, Sibylle von Vietinghoff

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  • The role of autoimmunity and autoinflammation in giant cell arteritis: A systematic literature review.

    Autoimmunity reviews

    Authors: Valentin S Schäfer, Peter Brossart, Kenneth J Warrington, Christian Kurts, Georg W Sendtner, Clemens A Aden

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  • CD4 T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.

    Science translational medicine

    Authors: Hans-Joachim Paust, Ning Song, Donatella De Feo, Nariaki Asada, Selma Tuzlak, Yu Zhao, Jan-Hendrik Riedel, Malte Hellmig, Amirrtavarshni Sivayoganathan, Anett Peters, Anna Kaffke, Alina Borchers, Ulrich O Wenzel, Oliver M Steinmetz, Gisa Tiegs, Elisabeth Meister, Matthias Mack, Christian Kurts, Sibylle von Vietinghoff, Maja T Lindenmeyer, Elion Hoxha, Rolf A K Stahl, Tobias B Huber, Stefan Bonn, Catherine Meyer-Schwesinger, Thorsten Wiech, Jan-Eric Turner, Burkhard Becher, Christian F Krebs, Ulf Panzer

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    Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.

    Journal of hepatology

    Authors: Carl-Philipp Hackstein, Jasper Spitzer, Konstantinos Symeonidis, Helena Horvatic, Tanja Bedke, Babett Steglich, Sabine Klein, Lisa M Assmus, Alexandru Odainic, Jennifer Szlapa, Nina Kessler, Marc Beyer, Ricarda Schmithausen, Eicke Latz, Richard A Flavell, Natalio Garbi, Christian Kurts, Beate M Kümmerer, Jonel Trebicka, Axel Roers, Samuel Huber, Susanne V Schmidt, Percy A Knolle, Zeinab Abdullah

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  • Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell immunoprofiling.

    Frontiers in immunology

    Authors: Felix Schreibing, Monica T Hannani, Hyojin Kim, James S Nagai, Fabio Ticconi, Eleanor Fewings, Tore Bleckwehl, Matthias Begemann, Natalia Torow, Christoph Kuppe, Ingo Kurth, Jennifer Kranz, Dario Frank, Teresa M Anslinger, Patrick Ziegler, Thomas Kraus, Jürgen Enczmann, Vera Balz, Frank Windhofer, Paul Balfanz, Christian Kurts, Gernot Marx, Nikolaus Marx, Michael Dreher, Rebekka K Schneider, Julio Saez-Rodriguez, Ivan Costa, Sikander Hayat, Rafael Kramann

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    Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs.

    The Journal of clinical investigation

    Authors: Janine Becker-Gotot, Mirjam Meissner, Vadim Kotov, Blanca Jurado-Mestre, Andrea Maione, Andreas Pannek, Thilo Albert, Chrystel Flores, Frank A Schildberg, Paul A Gleeson, Birgit M Reipert, Johannes Oldenburg, Christian Kurts

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    Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.

    The Journal of experimental medicine

    Authors: Nina Kessler, Susanne F Viehmann, Calvin Krollmann, Karola Mai, Katharina M Kirschner, Hella Luksch, Prasanti Kotagiri, Alexander M C Böhner, Dennis Huugen, Carina C de Oliveira Mann, Simon Otten, Stefanie A I Weiss, Thomas Zillinger, Kristiyana Dobrikova, Dieter E Jenne, Rayk Behrendt, Andrea Ablasser, Eva Bartok, Gunther Hartmann, Karl-Peter Hopfner, Paul A Lyons, Peter Boor, Angela Rösen-Wolff, Lino L Teichmann, Peter Heeringa, Christian Kurts, Natalio Garbi

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