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featured publications

  • Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr.

    Nature communications

    Authors: Saeede Salehi, Abdolhossein Zare, Gianluca Prezza, Jakob Bader, Cornelius Schneider, Utz Fischer, Felix Meissner, Matthias Mann, Michael Briese, Michael Sendtner

  • Top publication

    Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation.

    Nature communications

    Authors: Jonathan J Swietlik, Stefanie Bärthel, Chiara Falcomatà, Diana Fink, Ankit Sinha, Jingyuan Cheng, Stefan Ebner, Peter Landgraf, Daniela C Dieterich, Henrik Daub, Dieter Saur, Felix Meissner

  • Influence of circadian clocks on adaptive immunity and vaccination responses.

    Nature communications

    Authors: Louise Madeleine Ince, Coline Barnoud, Lydia Kay Lutes, Robert Pick, Chen Wang, Flore Sinturel, Chien-Sin Chen, Alba de Juan, Jasmin Weber, Stephan J Holtkamp, Sophia Martina Hergenhan, Jennifer Geddes-McAlister, Stefan Ebner, Paola Fontannaz, Benjamin Meyer, Maria Vono, Stéphane Jemelin, Charna Dibner, Claire-Anne Siegrist, Felix Meissner, Frederik Graw, Christoph Scheiermann

  • Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status.

    Cell reports. Medicine

    Authors: Jakob Maximilian Bader, Nikolaus Deigendesch, Martin Misch, Matthias Mann, Arend Koch, Felix Meissner

  • A Multi-Omics Approach Reveals Features That Permit Robust and Widespread Regulation of IFN-Inducible Antiviral Effectors.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Loránd Göczi, Mária Csumita, Attila Horváth, Gergely Nagy, Szilárd Póliska, Matteo Pigni, Christoph Thelemann, Bence Dániel, Hamidreza Mianesaz, Tamás Varga, Kaushik Sen, Sunil K Raghav, John W Schoggins, Laszlo Nagy, Hans Acha-Orbea, Felix Meissner, Walter Reith, Lajos Széles

  • Top publication

    P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection.

    The Journal of experimental medicine

    Authors: Lea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, Anja vom Hemdt, Jennifer D Wuerth, Lisa D J Schiffelers, Yonas M Tesfamariam, Florian N Gohr, Laura Klein, Ines H Kaltheuner, Stefan Ebner, Dorothee J Lapp, Jacob Mayer, Jonas Moecking, Hidde L Ploegh, Eicke Latz, Felix Meissner, Matthias Geyer, Beate M Kümmerer, Florian I Schmidt

  • Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.

    EMBO reports

    Authors: Henrick Riemenschneider, Qiang Guo, Jakob Bader, Frédéric Frottin, Daniel Farny, Gernot Kleinberger, Christian Haass, Matthias Mann, F Ulrich Hartl, Wolfgang Baumeister, Mark S Hipp, Felix Meissner, Rubén Fernández-Busnadiego, Dieter Edbauer

  • The emerging role of mass spectrometry-based proteomics in drug discovery.

    Nature reviews. Drug discovery

    Authors: Felix Meissner, Jennifer Geddes-McAlister, Matthias Mann, Marcus Bantscheff

  • Congenital deficiency reveals critical role of ISG15 in skin homeostasis.

    The Journal of clinical investigation

    Authors: Muhammad Nasir Hayat Malik, Syed Fakhar-Ul-Hassnain Waqas, Jana Zeitvogel, Jingyuan Cheng, Robert Geffers, Zeinab Abu-Elbaha Gouda, Ahmed Mahrous Elsaman, Ahmed R Radwan, Matthias Schefzyk, Peter Braubach, Bernd Auber, Ruth Olmer, Mathias Müsken, Lennart M Roesner, Gisa Gerold, Sven Schuchardt, Sylvia Merkert, Ulrich Martin, Felix Meissner, Thomas Werfel, Frank Pessler

  • Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.

    Nature cancer

    Authors: Chiara Falcomatà, Stefanie Bärthel, Sebastian A Widholz, Christian Schneeweis, Juan José Montero, Albulena Toska, Jonas Mir, Thorsten Kaltenbacher, Jeannine Heetmeyer, Jonathan J Swietlik, Jing-Yuan Cheng, Bianca Teodorescu, Oliver Reichert, Constantin Schmitt, Kathrin Grabichler, Andrea Coluccio, Fabio Boniolo, Christian Veltkamp, Magdalena Zukowska, Angelica Arenas Vargas, Woo Hyun Paik, Moritz Jesinghaus, Katja Steiger, Roman Maresch, Rupert Öllinger, Tim Ammon, Olga Baranov, Maria S Robles, Julia Rechenberger, Bernhard Kuster, Felix Meissner, Maximilian Reichert, Michael Flossdorf, Roland Rad, Marc Schmidt-Supprian, Günter Schneider, Dieter Saur