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featured publications

  • Plasma proteomic signatures of liver steatosis and fibrosis in people living with HIV: a cross-sectional study.

    EBioMedicine

    Authors: Louise E van Eekeren, Quirijn de Mast, Elise M G Meeder, Adriana Navas, Albert L Groenendijk, Marc J T Blaauw, Wilhelm A J W Vos, Nadira Vadaq, Jéssica C Dos Santos, Joost Rutten, Niels P Riksen, Jan van Lunzen, Gert Weijers, Mihai G Netea, André J A M van der Ven, Eric T T L Tjwa, Leo A B Joosten

  • Persistent bone marrow hemozoin accumulation confers a survival advantage against bacterial infection via cell-intrinsic Myd88 signaling.

    Cell reports

    Authors: Yanhui Zhu, Qingxiang Gao, Jia Zhang, Yu Cheng, Shuzhen Yang, Ren Xu, Jing Yuan, Boris Novakovic, Mihai G Netea, Shih-Chin Cheng

  • Single high-fat challenge and trained innate immunity: A randomized controlled cross-over trial.

    iScience

    Authors: Julia van Tuijl, Julia I P van Heck, Harsh Bahrar, Wieteke Broeders, Johan Wijma, Yvonne M Ten Have, Martin Giera, Heidi Zweers-van Essen, Laura Rodwell, Leo A B Joosten, Mihai G Netea, Lydia A Afman, Siroon Bekkering, Niels P Riksen

  • Clinical exome sequencing data from patients with inborn errors of immunity: Cohort level diagnostic yield and the benefit of systematic reanalysis.

    Clinical immunology (Orlando, Fla.)

    Authors: Emil E Vorsteveld, Caspar I Van der Made, Sanne P Smeekens, Janneke H Schuurs-Hoeijmakers, Galuh Astuti, Heleen Diepstra, Christian Gilissen, Evelien Hoenselaar, Alice Janssen, Kees van Roozendaal, Jettie Sikkema-van Engelen, Wouter Steyaert, Marjan M Weiss, Helger G Yntema, Tuomo Mantere, Mofareh S AlZahrani, Koen van Aerde, Beata Derfalvi, Eissa Ali Faqeih, Stefanie S V Henriet, Elise van Hoof, Eman Idressi, Thomas B Issekutz, Marjolijn C J Jongmans, Riikka Keski-Filppula, Ingrid Krapels, Maroeska Te Loo, Catharina M Mulders-Manders, Jaap Ten Oever, Judith Potjewijd, Nora Tarig Sarhan, Marjan C Slot, Paulien A Terhal, Herman Thijs, Anthony Vandersteen, Els K Vanhoutte, Frank van de Veerdonk, Gijs van Well, Mihai G Netea, Annet Simons, Alexander Hoischen, Rob J W Arts, Else M Bijker, Mariolina Bruno, Willemijn Hobo, Esther Hoppenreijs, Marien I de Jonge, Arjan van Laarhoven, Renate van der Molen, Manon Oud, Ellen J H Schatorje, Ruben Smeets, Evelien G G Sprenkeler, Kim Stol, Lilly M Verhagen, Evelien Zonneveld-Huijssoon

  • Mental health and its consequences in people living with HIV: A network approach.

    Brain and behavior

    Authors: Elise M G Meeder, Louise E van Eekeren, Marc J T Blaauw, Albert L Groenendijk, Wilhelm A J W Vos, Jan van Lunzen, Leo A B Joosten, Mihai G Netea, Quirijn de Mast, Willem L Blok, Annelies Verbon, Marvin A H Berrevoets, Vasiliki Matzaraki, Andre J A M van der Ven, Arnt F A Schellekens

  • TCA metabolism regulates DNA hypermethylation in LPS and -induced immune tolerance.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Abhimanyu, Santiago Carrero Longlax, Tomoki Nishiguchi, Malik Ladki, Daanish Sheikh, Amera L Martinez, Emily M Mace, Sandra L Grimm, Thaleia Caldwell, Alexandra Portillo Varela, Rajagopal V Sekhar, Anna M Mandalakas, Mandla Mlotshwa, Sibuse Ginidza, Jeffrey D Cirillo, Robert S Wallis, Mihai G Netea, Reinout van Crevel, Cristian Coarfa, Andrew R DiNardo

  • Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis.

    The Journal of infection

    Authors: Muhammed D Aksu, Tijmen van der Ent, Zhenhua Zhang, Anca L Riza, Aline H de Nooijer, Isis Ricaño-Ponce, Nico Janssen, Job J Engel, Ioana Streata, Helga Dijkstra, Heidi Lemmers, Inge Grondman, Valerie A C M Koeken, Eleni Antoniadou, Nikolaos Antonakos, Frank L van de Veerdonk, Yang Li, Evangelos J Giamarellos-Bourboulis, Mihai G Netea, Athanasios Ziogas

  • Interleukin 38 reduces antigen-presentation capacity and antibody production after vaccination.

    Vaccine

    Authors: Lisa U Teufel, Esther J M Taks, Jelle van Gemert, Mihaela Neacsu, Konstantin Föhse, Joshua Gillard, Dimitri A Diavatopoulos, Marien I de Jonge, Mihai G Netea, Leo A B Joosten, Rob J W Arts

  • Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population.

    Science advances

    Authors: Saumya Kumar, Martijn Zoodsma, Nhan Nguyen, Rodrigo Pedroso, Stephanie Trittel, Peggy Riese, Javier Botey-Bataller, Liang Zhou, Ahmed Alaswad, Haroon Arshad, Mihai G Netea, Cheng-Jian Xu, Frank Pessler, Carlos A Guzmán, Luis Graca, Yang Li

  • Polymorphisms within autophagy-related genes as susceptibility biomarkers for pancreatic cancer: A meta-analysis of three large European cohorts and functional characterization.

    International journal of cancer

    Authors: Fernando Gálvez-Montosa, Giulia Peduzzi, José Manuel Sanchez-Maldonado, Rob Ter Horst, Antonio J Cabrera-Serrano, Manuel Gentiluomo, Angelica Macauda, Natalia Luque, Pelin Ünal, Francisco Javier García-Verdejo, Yang Li, José Antonio López López, Angelika Stein, H Bas Bueno-de-Mesquita, Paolo Giorgio Arcidiacono, Dalila Luciola Zanette, Christoph Kahlert, Francesco Perri, Pavel Soucek, Renata Talar-Wojnarowska, George E Theodoropoulos, Jakob R Izbicki, Hussein Tamás, Hanneke Van Laarhoven, Gennaro Nappo, Maria Chiara Petrone, Martin Lovecek, Roel C H Vermeulen, Kestutis Adamonis, Fernando Jesus Reyes-Zurita, Bernd Holleczek, Jolanta Sumskiene, Beatrice Mohelníková-Duchoňová, Rita T Lawlor, Raffaele Pezzilli, Mateus Nobrega Aoki, Claudio Pasquali, Vitalija Petrenkiene, Daniela Basso, Stefania Bunduc, Annalisa Comandatore, Hermann Brenner, Stefano Ermini, Giuseppe Vanella, Mara R Goetz, Livia Archibugi, Maurizio Lucchesi, Faik Guntac Uzunoglu, Olivier Busch, Anna Caterina Milanetto, Marta Puzzono, Juozas Kupcinskas, Luca Morelli, Cosimo Sperti, Silvia Carrara, Gabriele Capurso, Casper H J van Eijck, Martin Oliverius, Susanne Roth, Francesca Tavano, Rudolf Kaaks, Andrea Szentesi, Ludmila Vodickova, Claudio Luchini, Ben Schöttker, Stefano Landi, Orsolya Dohan, Matteo Tacelli, William Greenhalf, Maria Gazouli, John P Neoptolemos, Giulia Martina Cavestro, Ugo Boggi, Anna Latiano, Péter Hegyi, Laura Ginocchi, Mihai G Netea, Pedro Sánchez-Rovira, Federico Canzian, Daniele Campa, Juan Sainz