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featured publications

  • Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen.

    eLife

    Authors: Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

  • Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV.

    Aging cell

    Authors: Adriana Navas, Vasiliki Matzaraki, Louise E van Eekeren, Marc J T Blaauw, Albert L Groenendijk, Wilhelm A J W Vos, Maartje Jacobs-Cleophas, Jéssica C Dos Santos, André J A M van der Ven, Leo A B Joosten, Mihai G Netea

  • Host-Directed Therapy in Pandemic Preparedness.

    JAMA

    Authors: Mihai G Netea, Frank L van de Veerdonk, Evangelos J Giamarellos-Bourboulis

  • Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia.

    Nature communications

    Authors: Todia P Setiabudiawan, Lika Apriani, Ayesha J Verrall, Fitria Utami, Marion Schneider, Agnes R Indrati, Pauline P Halim, Paulina Kaplonek, Hadar Malca, Jessica Shih-Lu Lee, Simone J C F M Moorlag, L Charlotte J de Bree, Vera P Mourits, Leo A B Joosten, Mihai G Netea, Bachti Alisjahbana, Ryan P McNamara, Galit Alter, Arjan van Laarhoven, James E Ussher, Katrina Sharples, Valerie A C M Koeken, Philip C Hill, Reinout van Crevel

  • Impact of COVID-19, lockdowns and vaccination on immune responses in a HIV cohort in the Netherlands.

    Frontiers in immunology

    Authors: Twan Otten, Xun Jiang, Manoj Kumar Gupta, Nadira Vadaq, Maartje Cleophas-Jacobs, Jéssica C Dos Santos, Albert Groenendijk, Wilhelm Vos, Louise E van Eekeren, Marc J T Blaauw, Elise M G Meeder, Olivier Richel, Vasiliki Matzaraki, Jan van Lunzen, Leo A B Joosten, Yang Li, Cheng-Jian Xu, Andre van der Ven, Mihai G Netea

  • Effects of delayed consent on patient characteristics in adult patients with sepsis.

    Intensive care medicine

    Authors: Frank Bloos, Holger Bogatsch, Mihai G Netea, Evangelos J Giamarellos-Bourboulis, Michael Bauer

  • Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response.

    Cell reports. Medicine

    Authors: Rachel Brandes-Leibovitz, Anca Riza, Gal Yankovitz, Andrei Pirvu, Stefania Dorobantu, Adina Dragos, Ioana Streata, Isis Ricaño-Ponce, Aline de Nooijer, Florentina Dumitrescu, Nikolaos Antonakos, Eleni Antoniadou, George Dimopoulos, Ioannis Koutsodimitropoulos, Theano Kontopoulou, Dimitra Markopoulou, Eleni Aimoniotou, Apostolos Komnos, George N Dalekos, Mihai Ioana, Evangelos J Giamarellos-Bourboulis, Irit Gat-Viks, Mihai G Netea

  • Trained innate immunity in response to nuclear antigens in systemic lupus erythematosus.

    Journal of autoimmunity

    Authors: Cansu Yanginlar, Nils Rother, Tomas G J M Post, Maaike Jacobs, Inge Jonkman, Montsy Brouns, Sybren Rinzema, Joost H A Martens, Michiel Vermeulen, Leo A B Joosten, Mihai G Netea, Luuk B Hilbrands, Zaheeb A Choudhry, Johan van der Vlag, Raphaël Duivenvoorden

  • Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra- IL-1R immune evasion strategies of emerging fungal pathogen Candida auris.

    PLoS pathogens

    Authors: Abishek Balakumar, Diprasom Das, Abhishek Datta, Abtar Mishra, Garrett Bryak, Shrihari M Ganesh, Mihai G Netea, Vinod Kumar, Michail S Lionakis, Devender Arora, Jyothi Thimmapuram, Shankar Thangamani

  • Interleukin-10 inhibits important components of trained immunity in human monocytes.

    Journal of leukocyte biology

    Authors: Rutger J Röring, Flavia Scognamiglio, Lisanne C de Jong, Laszlo A Groh, Vasiliki Matzaraki, Valerie A C M Koeken, Leo A B Joosten, Athanasios Ziogas, Mihai G Netea