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featured publications

  • BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation.

    The EMBO journal

    Authors: Lena Wischhof, Hang-Mao Lee, Janine Tutas, Clemens Overkott, Eileen Tedt, Miriam Stork, Michael Peitz, Oliver Brüstle, Thomas Ulas, Kristian Händler, Joachim L Schultze, Dan Ehninger, Pierluigi Nicotera, Paolo Salomoni, Daniele Bano

  • hCoCena: horizontal integration and analysis of transcriptomics datasets.

    Bioinformatics (Oxford, England)

    Authors: Marie Oestreich, Lisa Holsten, Shobhit Agrawal, Kilian Dahm, Philipp Koch, Han Jin, Matthias Becker, Thomas Ulas

  • Human variation in population-wide gene expression data predicts gene perturbation phenotype.

    iScience

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Caterina Carraro, Laura L Sun, Benedikt Reiz, Ioanna Gemünd, Adem Saglam, Souad Rahmouni, Michel Georges, Peer Arts, Alexander Hoischen, Leo A B Joosten, Frank L van de Veerdonk, Mihai G Netea, Kristian Händler, Sach Mukherjee, Thomas Ulas, Joachim L Schultze, Anna C Aschenbrenner

  • A guide to systems-level immunomics.

    Nature immunology

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Thomas Ulas, Anna C Aschenbrenner, Marc Beyer, Joachim L Schultze

  • Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state.

    eLife

    Authors: Caterina Carraro, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Arik Horne, Marie Oestreich, Stefanie Warnat-Herresthal, Tim Helbing, Michele De Franco, Kristian Haendler, Sach Mukherjee, Thomas Ulas, Valentina Gandin, Richard Goettlich, Anna C Aschenbrenner, Joachim L Schultze, Barbara Gatto

  • Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation.

    Frontiers in immunology

    Authors: Kevin Baßler, Wataru Fujii, Theodore S Kapellos, Erika Dudkin, Nico Reusch, Ari Horne, Benedikt Reiz, Malte D Luecken, Collins Osei-Sarpong, Stefanie Warnat-Herresthal, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Allon Wagner, Patrick Günther, Carmen Pizarro, Tina Schreiber, Rainer Knoll, Lisa Holsten, Charlotte Kröger, Elena De Domenico, Matthias Becker, Kristian Händler, Christian T Wohnhaas, Florian Baumgartner, Meike Köhler, Heidi Theis, Michael Kraut, Marc H Wadsworth, Travis K Hughes, Humberto J Ferreira, Emily Hinkley, Ines H Kaltheuner, Matthias Geyer, Christoph Thiele, Alex K Shalek, Andreas Feißt, Daniel Thomas, Henning Dickten, Marc Beyer, Patrick Baum, Nir Yosef, Anna C Aschenbrenner, Thomas Ulas, Jan Hasenauer, Fabian J Theis, Dirk Skowasch, Joachim L Schultze

  • Mature neutrophils and a NF-κB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19.

    Cell reports. Medicine

    Authors: Amit Frishberg, Emma Kooistra, Melanie Nuesch-Germano, Tal Pecht, Neta Milman, Nico Reusch, Stefanie Warnat-Herresthal, Niklas Bruse, Kristian Händler, Heidi Theis, Michael Kraut, Esther van Rijssen, Bram van Cranenbroek, Hans Jpm Koenen, Hidde Heesakkers, Mark van den Boogaard, Marieke Zegers, Peter Pickkers, Matthias Becker, Anna C Aschenbrenner, Thomas Ulas, Fabian J Theis, Shai S Shen-Orr, Joachim L Schultze, Matthijs Kox

  • Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus.

    Nature neuroscience

    Authors: Phan Q Duy, Stefan C Weise, Claudia Marini, Xiao-Jun Li, Dan Liang, Peter J Dahl, Shaojie Ma, Ana Spajic, Weilai Dong, Jane Juusola, Emre Kiziltug, Adam J Kundishora, Sunil Koundal, Maysam Z Pedram, Lucia A Torres-Fernández, Kristian Händler, Elena De Domenico, Matthias Becker, Thomas Ulas, Stefan A Juranek, Elisa Cuevas, Le Thi Hao, Bettina Jux, André M M Sousa, Fuchen Liu, Suel-Kee Kim, Mingfeng Li, Yiying Yang, Yutaka Takeo, Alvaro Duque, Carol Nelson-Williams, Yonghyun Ha, Kartiga Selvaganesan, Stephanie M Robert, Amrita K Singh, Garrett Allington, Charuta G Furey, Andrew T Timberlake, Benjamin C Reeves, Hannah Smith, Ashley Dunbar, Tyrone DeSpenza, June Goto, Arnaud Marlier, Andres Moreno-De-Luca, Xin Yu, William E Butler, Bob S Carter, Evelyn M R Lake, R Todd Constable, Pasko Rakic, Haifan Lin, Engin Deniz, Helene Benveniste, Nikhil S Malvankar, Juvianee I Estrada-Veras, Christopher A Walsh, Seth L Alper, Joachim L Schultze, Katrin Paeschke, Angelika Doetzlhofer, F Gregory Wulczyn, Sheng Chih Jin, Richard P Lifton, Nenad Sestan, Waldemar Kolanus, Kristopher T Kahle

  • Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States.

    Cells

    Authors: Lena F Schimke, Alexandre H C Marques, Gabriela Crispim Baiocchi, Caroline Aliane de Souza Prado, Dennyson Leandro M Fonseca, Paula Paccielli Freire, Desirée Rodrigues Plaça, Igor Salerno Filgueiras, Ranieri Coelho Salgado, Gabriel Jansen-Marques, Antonio Edson Rocha Oliveira, Jean Pierre Schatzmann Peron, Gustavo Cabral-Miranda, José Alexandre Marzagão Barbuto, Niels Olsen Saraiva Camara, Vera Lúcia Garcia Calich, Hans D Ochs, Antonio Condino-Neto, Katherine A Overmyer, Joshua J Coon, Joseph Balnis, Ariel Jaitovich, Jonas Schulte-Schrepping, Thomas Ulas, Joachim L Schultze, Helder I Nakaya, Igor Jurisica, Otávio Cabral-Marques

  • Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs.

    Nature communications

    Authors: Jan Langkabel, Arik Horne, Lorenzo Bonaguro, Lisa Holsten, Tatiana Hesse, Alexej Knaus, Yannick Riedel, Matthias Becker, Kristian Händler, Tarek Elmzzahi, Kevin Bassler, Nico Reusch, Leon Harootoonovtch Yeghiazarian, Tal Pecht, Adem Saglam, Thomas Ulas, Anna C Aschenbrenner, Franziska Kaiser, Caroline Kubaczka, Joachim L Schultze, Hubert Schorle